Publication Beamlines Strategic Pillar
Solomonson, Matthew; Huesgen, Pitter F.; Wasney, Gregory A.; Watanabe, Nobuhiko; Gruninger, Robert J. et al. (2013). Structure of the Mycosin-1 Protease from the Mycobacterial ESX-1 Protein Type VII Secretion System. Journal of Biological Chemistry 288(24) , 17782-17790. 10.1074/jbc.m113.462036. [PDB: 4j94, 4kpg] CMCF-BM Health
Singh, Rahul; Grigg, Jason C.; Armstrong, Zachary; Murphy, Michael E.P.; Eltis, Lindsay D. et al. (2012). Distal Heme Pocket Residues of B-type Dye-decolorizing Peroxidase. Journal of Biological Chemistry 287(13) , 10623-10630. 10.1074/jbc.m111.332171. [PDB: 3vec, 3ved, 3vee, 3vef, 3veg] CMCF-BM Health
Lee, Jaeyong; Taneva, Svetla G.; Holland, Bryan W.; Tieleman, D. Peter; Cornell, Rosemary B. et al. (2014). Structural Basis for Autoinhibition of CTP:Phosphocholine Cytidylyltransferase (CCT), the Regulatory Enzyme in Phosphatidylcholine Synthesis, by Its Membrane-binding Amphipathic Helix. Journal of Biological Chemistry 289(3) , 1742-1755. 10.1074/jbc.m113.526970. [PDB: 4mvc, 4mvd] CMCF-BM, CMCF-ID Health
Wheatley, Robert W.; Lo, Summie; Jancewicz, Larisa J.; Dugdale, Megan L.; Huber, Reuben E. et al. (2013). Structural Explanation for Allolactose (lac Operon Inducer) Synthesis by lacZ β-Galactosidase and the Evolutionary Relationship between Allolactose Synthesis and the lac Repressor. Journal of Biological Chemistry 288(18) , 12993-13005. 10.1074/jbc.m113.455436. [PDB: 4duw, 4dux] CMCF-BM Health
Zhang, Xiaolu Linda; Tibbits, Glen F.; Paetzel, Mark (2013). The structure of cardiac troponin C regulatory domain with bound Cd2+reveals a closed conformation and unique ion coordination. Acta Crystallographica Section D Biological Crystallography 69(5) , 722-734. 10.1107/s0907444913001182. [PDB: 3sd6, 4gje, 4gjf, 4gjg] CMCF-BM, CMCF-ID Health
Szabla, Robert; Li, Mingyi; Warner, Victoria; Song, Yifeng; Junop, Murray et al. (2024). DdrC, a unique DNA repair factor from D. radiodurans, senses and stabilizes DNA breaks through a novel lesion-recognition mechanism. Nucleic Acids Research 52(15) , 9282-9302. 10.1093/nar/gkae635. CMCF-BM, CMCF-ID Health
Carbone, Christine E.; Schönherr, Heike; Zhao, Victor Y.; Pierce, Levi; He, Jing et al. (2026). Cryptic small-molecule binding sites in the ARID1B DNA-binding domain. Proceedings of the National Academy of Sciences of the United States of America 123(33) . 10.1073/pnas.2529603123. CMCF-ID Health
Andress, Sam; McLeod, Matthew J.; Holyoak, Todd (2026). The C117D oxidation mimic reveals the monomeric structure of SARS ‐ CoV ‐2 main protease. Protein Science 35(9) . 10.1002/pro.70753. CMCF-ID Health
Dolgova, Natalia; Uhlemann, Eva-Maria E; Boniecki, Michal T; Vizeacoumar, Frederick S; Ara, Anjuman et al. (2024). MEMO1 binds iron and modulates iron homeostasis in cancer cells. eLife 13. 10.7554/elife.86354. CMCF-BM, CMCF-ID Health
Naineni, Sai Kiran; Bhatt, Garvit; Jiramongkolsiri, Ekkanat; Robert, Francis; Cencic, Regina et al. (2024). Protein–RNA interactions mediated by silvestrol—insight into a unique molecular clamp. Nucleic Acids Research 52(20) , 12701-12711. 10.1093/nar/gkae824. CMCF-ID Health
Kozlov, Guennadi; Jiang, Jianning; Rutherford, Tyler; Noronha, Anne M.; Wilds, Christopher J. et al. (2024). Enhanced binding of guanylated poly(A) RNA by the LaM domain of LARP1. RNA Biology 21(1) , 764-773. 10.1080/15476286.2024.2379121. CMCF-ID Health
Chen, Pu; Van Oers, Tayla J.; Arutyunova, Elena; Fischer, Conrad; Wang, Chaoxiang et al. (2024). A Structural Comparison of Oral SARS-CoV-2 Drug Candidate Ibuzatrelvir Complexed with the Main Protease (Mpro) of SARS-CoV-2 and MERS-CoV. JACS Au 4(8) , 3217-3227. 10.1021/jacsau.4c00508. CMCF-ID Health
Fraser, Bryan J.; Young, Nicholas J.; Bender, Brian J.; Gahbauer, Stefan; Ilyassov, Olzhas et al. (2025). Large Library Docking and Biophysical Analysis of Small-Molecule TMPRSS2 Inhibitors. Journal of Medicinal Chemistry 68(19) , 19893-19907. 10.1021/acs.jmedchem.4c03089. CMCF-ID Health
Fraser, Bryan J.; Wilson, Ryan P.; Ferková, Sára; Ilyassov, Olzhas; Lac, Jackie et al. (2025). Structural basis of TMPRSS11D specificity and autocleavage activation. Nature Communications 16(1) . 10.1038/s41467-025-59677-3. CMCF-ID Health
Puumala, Emily; Nandakumar, Meganathan; Yiu, Bonnie; Stogios, Peter J.; Strickland, Benjamin G. et al. (2025). Structure-guided optimization of small molecules targeting Yck2 as a strategy to combat Candida albicans. Nature Communications 16(1) . 10.1038/s41467-025-57346-z. CMCF-ID Health