Publication Beamlines Strategic Pillar
Gregg, Katie J.; Suits, Michael D.L.; Deng, Lehua; Vocadlo, David J.; Boraston, Alisdair B. et al. (2015). Structural Analysis of a Family 101 Glycoside Hydrolase in Complex with Carbohydrates Reveals Insights into Its Mechanism. Journal of Biological Chemistry 290(42) , 25657-25669. 10.1074/jbc.m115.680470. CMCF-ID Health
Heald, Robert; Bowman, Krista K.; Bryan, Marian C.; Burdick, Daniel; Chan, Bryan et al. (2015). Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study. Journal of Medicinal Chemistry 58(22) , 8877-8895. 10.1021/acs.jmedchem.5b01412. [PDB: 5cal, 5cao, 5cap] CMCF-ID Health
Ndubaku, Chudi O.; Crawford, James J.; Drobnick, Joy; Aliagas, Ignacio; Campbell, David et al. (2015). Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pKa Polar Moiety. ACS Medicinal Chemistry Letters 6(12) , 1241-1246. 10.1021/acsmedchemlett.5b00398. CMCF-ID Health
Parker, Michelle L.; Penarete-Vargas, Diana M.; Hamilton, Phineas T.; Guérin, Amandine; Dubey, Jitender P. et al. (2015). Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA–RON2 pair. Proceedings of the National Academy of Sciences of the United States of America 113(2) , 398-403. 10.1073/pnas.1515898113. [PDB: 4z80, 4z81] CMCF-ID Health
Raheem, Izzat T.; Walji, Abbas M.; Klein, Daniel; Sanders, John M.; Powell, David A. et al. (2015). Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors. Journal of Medicinal Chemistry 58(20) , 8154-8165. 10.1021/acs.jmedchem.5b01037. [PDB: 4ztf] CMCF-ID Health
Robb, Melissa; Robb, Craig S.; Higgins, Melanie A.; Hobbs, Joanne K.; Paton, James C. et al. (2015). A Second β-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans. Journal of Biological Chemistry 290(52) , 30888-30900. 10.1074/jbc.m115.688630. [PDB: 5a6a, 5a6b, 5a6k, 5ac5] CMCF-ID Health
Scapin, Giovanna; Yang, Xiaoyu; Prosise, Winifred W; McCoy, Mark; Reichert, Paul et al. (2015). Structure of full-length human anti-PD1 therapeutic IgG4 antibody pembrolizumab. Nature Structural and Molecular Biology 22(12) , 953-958. 10.1038/nsmb.3129. [PDB: 5dk3] CMCF-ID Health
Shin, Youngsook; Suchomel, Julia; Cardozo, Mario; Duquette, Jason; He, Xiao et al. (2015). Discovery, Optimization, and in Vivo Evaluation of Benzimidazole Derivatives AM-8508 and AM-9635 as Potent and Selective PI3Kδ Inhibitors. Journal of Medicinal Chemistry 59(1) , 431-447. 10.1021/acs.jmedchem.5b01651. [PDB: 5eds] CMCF-ID Health
Zhang, Qi; Fan, Lixin; Hou, Feng; Dong, Aiping; Wang, Yun-Xing et al. (2015). New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities of Roquins. Scientific Reports 5(1) . 10.1038/srep15660. [PDB: 4z30] CMCF-ID Health
Bacik, John-Paul; Klesmith, Justin R.; Whitehead, Timothy A.; Jarboe, Laura R.; Unkefer, Clifford J. et al. (2015). Producing Glucose 6-Phosphate from Cellulosic Biomass. Journal of Biological Chemistry 290(44) , 26638-26648. 10.1074/jbc.m115.674614. [PDB: 4yh5, 4zfv, 4zlu, 5bsb] CMCF-ID Agriculture
Hackett, Mark J.; Smith, Shari. E; Caine, Sally; Nichol, Helen; George, Graham N. et al. (2015). Novel bio-spectroscopic imaging reveals disturbed protein homeostasis and thiol redox with protein aggregation prior to hippocampal CA1 pyramidal neuron death induced by global brain ischemia in the rat. Free Radical Biology and Medicine 89, 806-818. 10.1016/j.freeradbiomed.2015.08.029. MID-IR Agriculture
Fawcett, Skya E.; Jamieson, Heather E.; Nordstrom, D. Kirk; McCleskey, R. Blaine (2015). Arsenic and antimony geochemistry of mine wastes, associated waters and sediments at the Giant Mine, Yellowknife, Northwest Territories, Canada. Applied Geochemistry 62, 3-17. 10.1016/j.apgeochem.2014.12.012. CLS-APS
Li, Xiyan; Liu, Xiaowang; Chevrier, Daniel M.; Qin, Xian; Xie, Xiaoji et al. (2015). Energy Migration Upconversion in Manganese(II)‐Doped Nanoparticles. Angewandte Chemie - International Edition 54(45) , 13312-13317. 10.1002/anie.201507176. CLS-APS
MacDonald, Tracy C.; Nehzati, Susan; Sylvain, Nicole J.; James, Ashley K.; Korbas, Malgorzata et al. (2015). Phenylthiourea alters toxicity of mercury compounds in zebrafish larvae. Journal of Inorganic Biochemistry 151, 10-17. 10.1016/j.jinorgbio.2015.07.003. CLS-APS
Marbella, Lauren E.; Chevrier, Daniel M.; Tancini, Peter D.; Shobayo, Olabobola; Smith, Ashley M. et al. (2015). Description and Role of Bimetallic Prenucleation Species in the Formation of Small Nanoparticle Alloys. Journal of the American Chemical Society 137(50) , 15852-15858. 10.1021/jacs.5b10124. CLS-APS