Publication Beamlines Strategic Pillar
Ireland, Kendra A.; Kayrouz, Chase M.; Abbott, Marissa L.; Seyedsayamdost, Mohammad R.; Davis, Katherine M. et al. (2025). Structural and functional analysis of SAM-dependent N-methyltransferases involved in ovoselenol and ovothiol biosynthesis. Structure . 10.1016/j.str.2024.12.020. CMCF-ID Health
Ezekiel, Sean J.; Searle, Mackenzie; Park, Jaeok (2025). Engineering dimer mutants of human geranylgeranyl pyrophosphate synthase. PLoS ONE 20(1) , e0317437. 10.1371/journal.pone.0317437. [PDB: 9csl] CMCF-ID Health
Cregg, James; Pota, Kristof; Tomlinson, Aidan C. A.; Yano, Jason; Marquez, Abby et al. (2025). Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c02313. [PDB: 9bfv, 9bfw] CMCF-ID Health
Cregg, James; Edwards, Anne V.; Chang, Stephanie; Lee, Bianca J.; Knox, John E. et al. (2025). Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c02314. [PDB: 9bg0, 9bg2, 9bg3, 9bg4, 9bg5, 9bg6, 9bg8, 9bga, 9bgb, 9bgc, 9bgd] CMCF-ID Health
Higgins, Melanie A.; Shi, Xinjie; Soler, Jordi; Harland, Jill B.; Parkkila, Taylor et al. (2025). Structure and mechanism of haem-dependent nitrogen–nitrogen bond formation in piperazate synthase. Nature Catalysis 8(3) , 207-217. 10.1038/s41929-024-01280-8. CMCF-ID Materials
Uguen, Mélanie; Shell, Devan J.; Silva, Madhushika; Deng, Yu; Li, Fengling et al. (2025). Potent and selective SETDB1 covalent negative allosteric modulator reduces methyltransferase activity in cells. Nature Communications 16(1) . 10.1038/s41467-025-57005-3. [PDB: 9cuw, 9cux] CMCF-BM Health
Tran, Norman; Redzic, Jasmina S.; Eisenmesser, Elan Z.; Holyoak, Todd (2025). The structure of the Gemella haemolysans M26 IgA1 protease trypsin-like domain. Acta Crystallographica Section F:Structural Biology Communications 81(4) . 10.1107/s2053230x25001219. [PDB: 9ect] CMCF-BM Health
Cottrell, Kevin M.; Briggs, Kimberly J.; Tsai, Alice; Tonini, Matthew R.; Whittington, Douglas A. et al. (2025). Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion. Journal of Medicinal Chemistry 68(5) , 5097-5119. 10.1021/acs.jmedchem.4c03067. [PDB: 9n3o] CMCF-BM Health
Colussi, Danielle M.; Grainger, Ryan; Noble, Megan; Lake, Taylor; Junop, Murray et al. (2025). Disrupting the network of co-evolving amino terminal domain residues relieves mitochondrial calcium uptake inhibition by MCUb. Computational and Structural Biotechnology Journal 27, 190-213. 10.1016/j.csbj.2024.12.007. [PDB: 8urg] CMCF-BM Health
Zhang, Qiang; Li, Jialiang; He, Guangyuan; Li, Junyan; Chen, Ziyi et al. (2025). Regulating Mono-/Binuclear Fe Species in Framework Al-Rich Zeolites for Efficient Low-Temperature Alkane Oxidation. CCS Chemistry 7(3) , 819-831. 10.31635/ccschem.024.202404123. CLS-APS Materials
Van Loon, Lisa L.; Finfrock, Y. Zou; Meira, Debora M.; Burgess, R. W.; Bevan, George et al. (2025). Finding a needle in a haystack: quantitative HERFD-XRF imaging and HERFD-XANES characterization of trace platinum in gold solidi from the Late Roman and Byzantine Empires. Journal of Analytical Atomic Spectrometry . 10.1039/d4ja00281d. CLS-APS Materials
Joe Ziehl, Tyler; Zhang, Peng (2025). Colloidal High Entropy Alloy Nanoparticles: Synthetic Strategies and Electrocatalytic Properties. ChemPhysChem 26(6) . 10.1002/cphc.202400853. CLS-APS Materials
Chen, Yuanjun; Wang, Xinyue; Li, Xiao-Yan; Miao, Rui Kai; Dong, Juncai et al. (2025). Electrified synthesis of n-propanol using a dilute alloy catalyst. Nature Catalysis 8(3) , 239-247. 10.1038/s41929-025-01301-0. CLS-APS Materials
Kaduk, James A.; Dosen, Anja; Blanton, Thomas N. (2025). Crystal structure of flumethasone, C22H28F2O5. Powder Diffraction , 1-6. 10.1017/s0885715625000120. BXDS-WLE Health
Kaduk, James A.; Dosen, Anja; Blanton, Thomas N. (2025). Crystal structure of diroximel fumarate, C11H13NO6. Powder Diffraction , 1-6. 10.1017/s0885715625000119. BXDS-WLE Health