| Kalliokoski, Tuomo; Kettunen, Henna; Kumpulainen, Esa; Kettunen, Emilia; Thieulin-Pardo, Gabriel et al. (2023). Discovery of novel methionine adenosyltransferase 2A (MAT2A) allosteric inhibitors by structure-based virtual screening. Bioorganic and Medicinal Chemistry Letters 94, 129450. 10.1016/j.bmcl.2023.129450. [PDB: 8p1t, 8p1v] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Kattar, Solomon D.; Gulati, Anmol; Margrey, Kaila A.; Keylor, Mitchell H.; Ardolino, Michael et al. (2023). Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c01486. [PDB: 8six] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Smith, Christopher R.; Chen, Dan; Christensen, James G.; Coulombe, René; Féthière, James et al. (2023). Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography. Journal of Medicinal Chemistry 67(1) , 774-781. 10.1021/acs.jmedchem.3c02140. [PDB: 8t5g, 8t5m, 8t5r] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Thai, Elaine; Murugan, Rajagopal; Binter, Špela; Burn Aschner, Clare; Prieto, Katherine et al. (2023). Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Reports 42(11) , 113330. 10.1016/j.celrep.2023.113330. [PDB: 8fb5] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Varkaris, Andreas; Pazolli, Ermira; Gunaydin, Hakan; Wang, Qi; Pierce, Levi et al. (2023). Discovery and clinical proof-of-concept of RLY-2608, a first-in-class mutant-selective allosteric PI3Ka inhibitor that decouples anti-tumor activity from hyperinsulinemia. Cancer Discovery . 10.1158/2159-8290.cd-23-0944. [PDB: 8ts7] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| 수아레즈 조안 세오아네; 폴게이라 주딧 아니도; 조 프란슨; 진-필리프 줄리엔; 스웨타 라만 et al. (2023). Antibodies to LIF and their uses. Patent Number: KR102599557B1. |
CMCF-ID |
Patent |
Health |
| Han Li; Dorothea Kominos; Jie Zhang; Alla Pritsker; Matthew Davison et al. (2023). Methods for treating inflammation using antibodies to kallidin and des-arg10-kallidin. Patent Number: US20230399388A1. |
CMCF-ID |
Patent |
Health |
| Joan Seoane Suarez; Judit Anido Folgueira; Johan Fransson; Jean-Philippe Julien; Swetha RAMAN et al. (2023). Antibodies against lif and uses thereof. Patent Number: EP3555132B1. |
CMCF-ID |
Patent |
Health |
| Bailey-Elkin, B.A.; Mark, B.L. (2023). PRRSV-1 PLP2 domain. Protein Data Bank: 8ehn. |
CMCF-ID |
PDB Deposition |
Health |
| Wang, F.; Cheng, W.; Yuan, Z.; Qi, J.; Li, J. et al. (2023). The Crystal Structure of integrase from Biortus. Protein Data Bank: 8wf7. |
CMCF-ID |
PDB Deposition |
Health |
| Wu, J.; Wang, F.; Gui, W.; Cheng, W.; Yang, Y. et al. (2023). Crystal structure of a bright green fluorescent protein (StayGold) with single mutation (K192Y) in jellyfish Cytaeis uchidae from Biortus. Protein Data Bank: 8gyf. |
CMCF-ID |
PDB Deposition |
Materials |
| Frigon, L.; Pascal, J.M. (2023). PARP4 catalytic domain. Protein Data Bank: 8sx1. |
CMCF-BM |
PDB Deposition |
Agriculture |
| Li, K.; Tokareva, O.S.; Thomson, T.M.; Verdine, G.L.; McGee, J.H. et al. (2023). Crystal structure of the WWP1 HECT domain in complex with H302, a Helicon Polypeptide. Protein Data Bank: 8ei4. |
CMCF-BM |
PDB Deposition |
Agriculture |
| Tran, T.T.Q.; Pham, N.T.H.; Calmettes, C.; Doucet, N. (2023). Crystal structure of human eosinophil-derived neurotoxin (EDN, ribonuclease 2) in complex with 5'-adenosine monophosphate (AMP). Protein Data Bank: 8f5x. |
CMCF-BM |
PDB Deposition |
Agriculture |
| Wang, F.; Cheng, W.; Lv, Z.; Ju, C.; Bao, C. et al. (2023). The Crystal Structure of JMJD2A(M1-L359) from Biortus.. Protein Data Bank: 8wd3. |
CMCF-BM |
PDB Deposition |
Agriculture |