Publication Beamlines Strategic Pillar
Kattar, Solomon D.; Gulati, Anmol; Margrey, Kaila A.; Keylor, Mitchell H.; Ardolino, Michael et al. (2023). Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c01486. [PDB: 8six] CMCF-ID Health
Thai, Elaine; Murugan, Rajagopal; Binter, Špela; Burn Aschner, Clare; Prieto, Katherine et al. (2023). Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Reports 42(11) , 113330. 10.1016/j.celrep.2023.113330. [PDB: 8fb5] CMCF-ID Health
Cole, Andrew G.; Kultgen, Steven G.; Mani, Nagraj; Quintero, Jorge G.; Yi Fan, Kristi et al. (2023). Design, synthesis, and structure-activity relationship of a bicyclic HBV capsid assembly modulator chemotype leading to the identification of clinical candidate AB-506. Bioorganic and Medicinal Chemistry Letters 94, 129456. 10.1016/j.bmcl.2023.129456. [PDB: 8gbu] CMCF-ID Health
Kalliokoski, Tuomo; Kettunen, Henna; Kumpulainen, Esa; Kettunen, Emilia; Thieulin-Pardo, Gabriel et al. (2023). Discovery of novel methionine adenosyltransferase 2A (MAT2A) allosteric inhibitors by structure-based virtual screening. Bioorganic and Medicinal Chemistry Letters 94, 129450. 10.1016/j.bmcl.2023.129450. [PDB: 8p1t, 8p1v] CMCF-ID Health
Wu, J.; Wang, F.; Gui, W.; Cheng, W.; Yang, Y. et al. (2023). Crystal structure of a bright green fluorescent protein (StayGold) with single mutation (K192Y) in jellyfish Cytaeis uchidae from Biortus. Protein Data Bank: 8gyf. CMCF-ID Materials
Xu, C.; Chung, I.Y.W.; Cygler, M. (2023). Crystal structure of legAS4 from Legionella pneumophila subsp. pneumophila with histone H3 (1-12)peptide. Protein Data Bank: 8swi. CMCF-BM Agriculture
Tran, T.T.Q.; Pham, N.T.H.; Calmettes, C.; Doucet, N. (2023). Crystal structure of human eosinophil-derived neurotoxin (EDN, ribonuclease 2) in complex with 5'-adenosine monophosphate (AMP). Protein Data Bank: 8f5x. CMCF-BM Agriculture
Wang, F.; Cheng, W.; Lv, Z.; Ju, C.; Wang, J. et al. (2023). The Crystal Structure of L-asparaginase from Biortus.. Protein Data Bank: 8wgq. CMCF-BM Agriculture
Wang, F.; Cheng, W.; Lv, Z.; Ju, C.; Wang, J. et al. (2023). The Crystal Structure of JNK3 from Biortus.. Protein Data Bank: 8wgf. CMCF-BM Agriculture
Wang, F.; Cheng, W.; Lv, Z.; Ju, C.; Bao, C. et al. (2023). The Crystal Structure of JMJD2A(M1-L359) from Biortus.. Protein Data Bank: 8wd3. CMCF-BM Agriculture
Frigon, L.; Pascal, J.M. (2023). PARP4 catalytic domain. Protein Data Bank: 8sx1. CMCF-BM Agriculture
Li, K.; Tokareva, O.S.; Thomson, T.M.; Verdine, G.L.; McGee, J.H. et al. (2023). Crystal structure of the WWP1 HECT domain in complex with H302, a Helicon Polypeptide. Protein Data Bank: 8ei4. CMCF-BM Agriculture
Ali, Mohamed (2023). Investigating the role of acetylation of LC3-family proteins in regulating autophagy. Supervisor: Omichinski, James G.. Quebec, Canada: Université de Montréal. http://hdl.handle.net/1866/32170. CMCF-BM Health
Hamdorf, Matthias; Imhof, Thomas; Bailey-Elkin, Ben; Betz, Janina; Theobald, Sebastian J et al. (2023). The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm. Journal of Molecular Cell Biology 15(10) . 10.1093/jmcb/mjad062. CMCF-BM Health
Penner, Tiffany V.; Cobo, Neil Lorente; Patel, Deepak T.; Patel, Dhruvin H.; Savchenko, Alexei et al. (2023). Structural characterization of the Sel1‐like repeat protein LceB from Legionella pneumophila. Protein Science . 10.1002/pro.4889. [PDB: 8sxq] CMCF-BM Health