Publication Beamlines Strategic Pillar
Blake, James F.; Burkard, Michael; Chan, Jocelyn; Chen, Huifen; Chou, Kang-Jye et al. (2016). Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development. Journal of Medicinal Chemistry 59(12) , 5650-5660. 10.1021/acs.jmedchem.6b00389. [PDB: 5k4i] CMCF-ID Health
Bie, H.Y.; Yin, J.; James, M.N.G.; TB Structural Genomics Consortium (TBSGC) (2016). Crystal structure of beta subunit of acyl-CoA carboxylase AccD1 from Mycobacterium tuberculosis. Protein Data Bank: 4q0g. CMCF-ID Health
Beyrakhova, K.; van Straaten, K.; Cygler, M. (2016). Structure of the effector protein LpiR1 (Lpg0634) from Legionella pneumophila. Protein Data Bank: 5jg4. CMCF-ID Health
Aydin, H.; Sultana, A.; Lee, J.E. (2016). Crystal structure of the human sperm Izumo1 residues 22-254. Protein Data Bank: 5f4t. CMCF-ID Health
Aydin, H.; Sultana, A.; Lee, J.E. (2016). Crystal structure of the human sperm Izumo1 and egg Juno complex. Protein Data Bank: 5f4e. CMCF-ID Health
Aydin, H.; Sultana, A.; Lee, J.E. (2016). Crystal structure of the human sperm Izumo1 residues 22-268. Protein Data Bank: 5f4v. CMCF-ID Health
Aydin, Halil; Sultana, Azmiri; Li, Sheng; Thavalingam, Annoj; Lee, Jeffrey E. et al. (2016). Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex. Nature 534(7608) , 562-565. 10.1038/nature18595. [PDB: 5f4e, 5f4t, 5f4v] CMCF-ID Health
Leaver-Fay, Andrew; Froning, Karen J.; Atwell, Shane; Aldaz, Hector; Pustilnik, Anna et al. (2016). Computationally Designed Bispecific Antibodies using Negative State Repertoires. Structure 24(4) , 641-651. 10.1016/j.str.2016.02.013. [PDB: 5dj0, 5dj2] CMCF-BM, CMCF-ID Materials
Hobbs, Joanne K.; Lee, Seunghyae M.; Robb, Melissa; Hof, Fraser; Barr, Christopher et al. (2016). KdgF, the missing link in the microbial metabolism of uronate sugars from pectin and alginate. Proceedings of the National Academy of Sciences of the United States of America 113(22) , 6188-6193. 10.1073/pnas.1524214113. [PDB: 5fpx, 5fpz] CMCF-ID Materials
Mazurkewich; Scott (2016). Characterization of the 4-carboxy-2-hydroxymuconate hydratase and the 4-carboxy-4-hydroxy-2-oxoadipate/4-hydroxy-4-methyl-2-oxoglutarate aldolase from Pseudomonas putida. Supervisor: Seah, Stephen. Ontario, Canada: University of Guelph. http://hdl.handle.net/10214/9677. CMCF-BM, CMCF-ID Agriculture
Mallette, E.; Ovchinnikova, O.G.; Whitfield, C.; Kimber, M.S. (2016). The structure of the beta-3-deoxy-D-manno-oct-2-ulosonic acid transferase domain from WbbB. Protein Data Bank: 5fa0. CMCF-BM Agriculture
Huang, J.; Fraser, M.E. (2016). Succinate bound to pig GTP-specific succinyl-CoA synthetase. Protein Data Bank: 5cae. CMCF-BM Agriculture
Sahtout, Naheda; Kuttiyatveetil, Jijin R. A.; Fodje, Michel; Sanders, David A. R. (2016). Putative thioredoxin Trx1 fromThermosipho africanusstrain TCF52B: expression, purification and structural determination using S-SAD. Acta Crystallographica Section F:Structural Biology Communications 72(6) , 443-447. 10.1107/s2053230x16007214. CMCF-BM Health
Ramaswamy; Raghavendran (2016). Structural characterization of TbFam50, TbPSSA2, and TCCISSA, surface proteins expressed by the trypanosome inside the tsetse vector. Supervisor: Boulanger, Martin. J. British Columbia, Canada: University of Victoria. http://hdl.handle.net/1828/7332. CMCF-BM, CMCF-ID Health
Ovchinnikova, Olga G.; Mallette, Evan; Koizumi, Akihiko; Lowary, Todd L.; Kimber, Matthew S. et al. (2016). Bacterial β-Kdo glycosyltransferases represent a new glycosyltransferase family (GT99). Proceedings of the National Academy of Sciences of the United States of America 113(22) , 3120-3129. 10.1073/pnas.1603146113. [PDB: 5fa0, 5fa1] CMCF-BM, CMCF-ID Health