Publication Beamlines Strategic Pillar
Raman, S.; Beilschmidt, M.; Fransson, J.; Julien, J.P. (2019). Crystal structure of Frizzled 5 CRD in complex with F2.I Fab. Protein Data Bank: 6o39. CMCF-ID Health
Raman, Swetha; Beilschmidt, Melissa; To, Minh; Lin, Kevin; Lui, Francine et al. (2019). Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies. Proceedings of the National Academy of Sciences of the United States of America 116(14) , 6812-6817. 10.1073/pnas.1817246116. [PDB: 6o39, 6o3a] CMCF-ID Health
Li, T.; Lin, S.X. (2019). CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPLEXED WITH ESTRONE AND NADP+. Protein Data Bank: 6mne. CMCF-ID Health
Li, Tang; Stephen, Preyesh; Zhu, Dao‐Wei; Shi, Rong; Lin, Sheng‐Xiang et al. (2019). Crystal structures of human 17β‐hydroxysteroid dehydrogenase type 1 complexed with estrone andNADP+reveal the mechanism of substrate inhibition. FEBS Journal 286(11) . 10.1111/febs.14784. [PDB: 6mne] CMCF-BM, CMCF-ID Health
Simonetta, K.R.; Clifton, M.C.; Walter, R.L.; Ranieri, G.M.; Carter, J.J. et al. (2019). Monophosphorylated pSer33 b-Catenin peptide bound to b-TrCP/Skp1 Complex. Protein Data Bank: 6m94. CMCF-ID Health
Simonetta, K.R.; Clifton, M.C.; Walter, R.L.; Ranieri, G.M.; Lee, S.J. et al. (2019). Monophosphorylated pSer33 b-Catenin peptide, b-TrCP/Skp1, NRX-1933 ternary complex. Protein Data Bank: 6m93. CMCF-ID Health
Simonetta, K.R.; Clifton, M.C.; Walter, R.L.; Ranieri, G.M.; Carter, J.J. et al. (2019). Monophosphorylated pSer33 b-Catenin peptide, b-TrCP/Skp1, NRX-2663 ternary complex. Protein Data Bank: 6m92. CMCF-ID Health
Simonetta, K.R.; Clifton, M.C.; Walter, R.L.; Ranieri, G.M.; Carter, J.J. et al. (2019). Monophosphorylated pSer33 b-Catenin peptide, b-TrCP/Skp1, NRX-103094 ternary complex. Protein Data Bank: 6m91. CMCF-ID Health
Brooks, C.L. (2019). Structure of VHH R419 isolated from a pre-immune phage display library. Protein Data Bank: 6dyx. CMCF-ID Health
Doyle, L.; Mallette, E.; Kimber, M.S. (2019). Escherichia coli KpsC, N-terminal domain. Protein Data Bank: 6mgc. CMCF-ID Health
Pluvinage, Benjamin; Fillo, Alexander; Massel, Patricia; Boraston, Alisdair B. (2017). Structural Analysis of a Family 81 Glycoside Hydrolase Implicates Its Recognition of β-1,3-Glucan Quaternary Structure. Structure 25(9) , 1348-1359.e3. 10.1016/j.str.2017.06.019. [PDB: 5t4a, 5t4c, 5t4g] CMCF-ID Health
Mangat, Chand S.; Vadlamani, Grishma; Holicek, Viktor; Chu, Mitchell; Larmour, Veronica L. C. et al. (2019). Molecular Basis for the Potent Inhibition of the Emerging Carbapenemase VCC-1 by Avibactam. Antimicrobial Agents and Chemotherapy 63(4) . 10.1128/aac.02112-18. [PDB: 6mk6] CMCF-BM, CMCF-ID Health
Heron, Paul W.; Abellán-Flos, Marta; Salmon, Laurent; Sygusch, Jurgen (2018). Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase. Journal of Medicinal Chemistry 61(23) , 10558-10572. 10.1021/acs.jmedchem.8b01000. [PDB: 5tle, 5tlh, 5tlw, 5tlz] CMCF-BM, CMCF-ID Health
Kiefer, J.R.; Vinogradova, M.; Liang, J.; Zhang, B.; Ortwine, D.F. et al. (2019). Crystal structure of estrogen receptor alpha in complex with receptor degrader 16aa. Protein Data Bank: 6dfn. CMCF-ID Health
Zhang, Birong; Kiefer, James R.; Blake, Robert A.; Chang, Jae H.; Hartman, Steven et al. (2019). Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha. Bioorganic and Medicinal Chemistry Letters 29(7) . 10.1016/j.bmcl.2019.01.036. [PDB: 6dfn] CMCF-ID Health