| Mahbub, Luba; Kozlov, Guennadi; Knorn, Caroline; Gehring, Kalle (2025). Structure of the phosphocysteine intermediate of the phosphatase of regenerating liver PTP4A1. Journal of Biological Chemistry , 110251. 10.1016/j.jbc.2025.110251. [PDB: 9mex] |
CMCF-ID |
Peer-Reviewed Article |
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| Vallée, Frédéric; Casás-Selves, Matias; Bubenik, Monica; Duplessis, Martin; Sow, Boubacar et al. (2025). Discovery of RP-1664: A First-in-Class Orally Bioavailable, Selective PLK4 Inhibitor. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.5c00529. [PDB: 9o63] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Ye, Qilu; Eves, Robert; Vance, Tyler D. R.; Hansen, Thomas; Sage, Adam P. et al. (2025). Aeromonas hydrophila
RTX adhesin has three ligand-binding domains that give the bacterium the potential to adhere to and aggregate a wide variety of cell types. mBio 16(5) . 10.1128/mbio.03158-24. [PDB: 9cse] |
CMCF-ID |
Peer-Reviewed Article |
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| Kinzel, Olaf; Goldberg, Steven D.; Cummings, Maxwell D.; Gege, Christian; Steeneck, Christoph et al. (2025). Identification of JNJ-61803534, a RORγt Inverse Agonist for the Treatment of Psoriasis. Journal of Medicinal Chemistry 68(8) , 8713-8728. 10.1021/acs.jmedchem.5c00390. [PDB: 9n9l] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Goncalves, Monica M.; Uday, Adwaith B.; Forrester, Taylor J. B.; Currie, S. Quinn W.; Kim, Angelina S. et al. (2025). Mechanism of allosteric activation in human mitochondrial ClpP protease. Proceedings of the National Academy of Sciences of the United States of America 122(16) . 10.1073/pnas.2419881122. [PDB: 9dqk, 9dql] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Nakhla, Mina C.; Comita, Janelle; Shapiro, Adam B.; Moussa, Samir H.; Chen, April et al. (2025). Small molecule inhibitors of mannan-binding lectin-associated serine Proteases-2 and-3. European Journal of Medicinal Chemistry 289, 117238. 10.1016/j.ejmech.2025.117238. [PDB: 9d17, 9d3y, 9d40, 9d4d] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Walker, Morgan E.; Zhu, Wei; Peterson, Janine H.; Wang, Hao; Patteson, Jon et al. (2025). Antibacterial macrocyclic peptides reveal a distinct mode of BamA inhibition. Nature Communications 16(1) . 10.1038/s41467-025-58086-w. [PDB: 9cs0, 9cs1] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Kin S. YANG; Hang CHU; Solomon H. REISBERG; Wai Yan CHOY; Brian P. BESTVATER et al. (2025). Reversible lysine covalent modifiers of cdk2 and uses thereof. Patent Number: WO2025090658. |
CMCF-ID |
Patent |
Health |
| Jean-Philippe Julien; Taylor Sicard; Anthony Semesi; Bebhinn Treanor; Tiantian Zhao et al. (2025). Nanoparticle platform for antibody and vaccine delivery. Patent Number: US20250114475A1. |
CMCF-ID |
Patent |
Health |
| Knudson-Goerner, E.J.; Boraston, A.B. (2025). The structure of a family 168 glycoside hydrolase from the marine bacterium Muricauda eckloniae.. Protein Data Bank: 9nhf. |
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PDB Deposition |
Agriculture |
| Thomsen, M.; Costanzi, E. (2025). The crystal structure of DNA-bound human MutSbeta (MSH2_E749A/MSH3_E976A) in the canonical mismatch bound conformation with ADP bound in MSH2. Protein Data Bank: 8rb2. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Walker, M.E.; Gu, M.; Lu, J.; Klein, D.J. (2025). E. coli BamA beta-barrel bound to darobactin and cyclic peptide CP2. Protein Data Bank: 9cs1. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Walker, M.E.; Gu, M.; Lu, J.; Klein, D.J. (2025). E. coli BamA beta-barrel bound to darobactin and cyclic peptide CP1. Protein Data Bank: 9cs0. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Pemberton, O.A.; Tong, Y.; Nocek, B.; Tang, H.Y.H. (2025). Crystal structure of WRN in complex with compound 43. Protein Data Bank: 9og8. |
CMCF-ID |
PDB Deposition |
Health |
| Szabla, R.; Junop, M.S.; Wood, K. (2025). Crystal structure of PprA S-F-S tetramer from Deinococcus radiodurans. Protein Data Bank: 9or6. |
CMCF-ID |
PDB Deposition |
Health |