Publication Beamlines Strategic Pillar
Caldwell, Shane J.; Huang, Yue; Berghuis, Albert M. (2016). Antibiotic Binding Drives Catalytic Activation of Aminoglycoside Kinase APH(2″)-Ia. Structure 24(6) , 935-945. 10.1016/j.str.2016.04.002. [PDB: 5byl, 5iqa, 5iqb, 5iqc, 5iqd, 5iqe, 5iqg, 5iqh] CMCF-ID Health
Bryson, Steve; Thomson, Christy A.; Risnes, Louise F.; Dasgupta, Somnath; Smith, Kenneth et al. (2016). Structures of Preferred Human IgV Genes–Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation. Journal of Immunology 196(11) , 4723-4730. 10.4049/jimmunol.1402890. [PDB: 4hh9, 4hha] CMCF-ID Health
Blake, James F.; Burkard, Michael; Chan, Jocelyn; Chen, Huifen; Chou, Kang-Jye et al. (2016). Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development. Journal of Medicinal Chemistry 59(12) , 5650-5660. 10.1021/acs.jmedchem.6b00389. [PDB: 5k4i] CMCF-ID Health
Aydin, Halil; Sultana, Azmiri; Li, Sheng; Thavalingam, Annoj; Lee, Jeffrey E. et al. (2016). Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex. Nature 534(7608) , 562-565. 10.1038/nature18595. [PDB: 5f4e, 5f4t, 5f4v] CMCF-ID Health
Nicklisch, Sascha C. T.; Rees, Steven D.; McGrath, Aaron P.; Gökirmak, Tufan; Bonito, Lindsay T. et al. (2016). Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure. Science Advances 2(4) , e1600001-e1600001. 10.1126/sciadv.1600001. [PDB: 4xwk] CMCF-ID Environment
Mazurkewich; Scott (2016). Characterization of the 4-carboxy-2-hydroxymuconate hydratase and the 4-carboxy-4-hydroxy-2-oxoadipate/4-hydroxy-4-methyl-2-oxoglutarate aldolase from Pseudomonas putida. Supervisor: Seah, Stephen. Ontario, Canada: University of Guelph. http://hdl.handle.net/10214/9677. CMCF-BM, CMCF-ID Agriculture
Blackler, Ryan J. (2016). Structural investigations into conformational diversity, polyspecificity, and binding mechanisms of near-germline antibodies. Supervisor: Evans, Stephen. BC, Canada: University of Victoria. http://hdl.handle.net/1828/7305. CMCF-ID Agriculture
Basu; Koli (2016). Discovery and characterization of an antifreeze protein from Lake Ontario midges. Supervisor: Davies, Peter. Ontario, Canada: Queen's University. http://hdl.handle.net/1974/14360. CMCF-ID Agriculture
Zhang, H.; Tempel, W.; Dong, A.; Bountra, C.; Arrowsmith, C.H. et al. (2016). Crystal Structure of the extended TUDOR domain from TDRD2. Protein Data Bank: 5j39. CMCF-ID Agriculture
Wroblewski, C.; Kimber, M.S. (2016). The structure of Escherichia coli ZapD. Protein Data Bank: 5dko. CMCF-ID Agriculture
Tang, Y.; Poy, F.; Bellon, S.F. (2016). TAF1(2) bound to a pyrrolopyridone compound. Protein Data Bank: 5i29. CMCF-ID Agriculture
McGrath, A.P.; Rees, S.D.; Chang, G. (2016). P-glycoprotein co-crystallized with BDE-100. Protein Data Bank: 4xwk. CMCF-ID Agriculture
Mallette, E.; Ovchinnikova, O.G.; Whitfield, C.; Kimber, M.S. (2016). The structure of the beta-3-deoxy-D-manno-oct-2-ulosonic acid transferase domain of WbbB. Protein Data Bank: 5fa1. CMCF-ID Agriculture
Jayaram, H.; Poy, F.; Setser, J.W.; Bellon, S.F. (2016). Crystal structure of the bromodomain of human CREBBP bound to the benzodiazepinone G02773986. Protein Data Bank: 5i83. CMCF-ID Agriculture
Hobbs, J.K.; Lee, S.M.; Robb, M.; Hof, F.; Barr, C. et al. (2016). The structure of KdgF from Yersinia enterocolitica with malonate bound in the active site.. Protein Data Bank: 5fpz. CMCF-ID Agriculture