| Zhou, Yan-Feng; Metcalf, Matthew C.; Garman, Scott C.; Edmunds, Tim; Qiu, Huawei et al. (2016). Human acid sphingomyelinase structures provide insight to molecular basis of Niemann–Pick disease. Nature Communications 7(1) . 10.1038/ncomms13082. [PDB: 5i8r] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Noach, Ilit; Ficko-Blean, Elizabeth; Pluvinage, Benjamin; Stuart, Christopher; Jenkins, Meredith L. et al. (2017). Recognition of protein-linked glycans as a determinant of peptidase activity. Proceedings of the National Academy of Sciences of the United States of America 114(5) , E679-E688. 10.1073/pnas.1615141114. [PDB: 5kd5, 5kd8, 5kdn, 5kdu, 5kdv, 5kdw, 5kdx] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Sobhanifar, Solmaz; Worrall, Liam J.; King, Dustin T.; Wasney, Gregory A.; Baumann, Lars et al. (2016). Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid β-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathogens 12(12) , e1006067. 10.1371/journal.ppat.1006067. [PDB: 5tzi, 5tzj, 5u02] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Ulaganathan, ThirumalaiSelvi; Shi, Rong; Yao, Deqiang; Gu, Ruo-Xu; Garron, Marie-Line et al. (2016). Conformational flexibility of PL12 family heparinases: structure and substrate specificity of heparinase III fromBacteroides thetaiotaomicron(BT4657). Glycobiology 27(2) , 176-187. 10.1093/glycob/cww096. [PDB: 5jmd, 5jmf] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Haji-Ghassemi, Omid; Gilbert, Michel; Spence, Jenifer; Schur, Melissa J.; Parker, Matthew J. et al. (2016). Molecular Basis for Recognition of the Cancer Glycobiomarker, LacdiNAc (GalNAc[β1→4]GlcNAc), by Wisteria floribunda Agglutinin. Journal of Biological Chemistry 291(46) , 24085-24095. 10.1074/jbc.m116.750463. [PDB: 5kxb, 5kxc, 5kxd, 5kxe] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Loewen, P.C. (2016). Crystal structure of the E198A variant of Burkholderia pseudomallei catalase-peroxidase KatG with INH. Protein Data Bank: 5sxx. |
CMCF-ID |
PDB Deposition |
Health |
| Loewen, P.C. (2016). Crystal structure of the E198A variant of catalase-peroxidase KatG of Burkholderia pseudomallei. Protein Data Bank: 5sxw. |
CMCF-ID |
PDB Deposition |
Health |
| Loewen, P.C. (2016). Crystal structure of the S324T variant of Burkholderia pseudomallei KatG with isonicotinic acid hydrazide bound. Protein Data Bank: 5sxt. |
CMCF-ID |
PDB Deposition |
Health |
| Loewen, P.C. (2016). Crystal structure of catalase-peroxidase KatG with isonicotinic acid hydrazide and AMP bound. Protein Data Bank: 5sxs. |
CMCF-ID |
PDB Deposition |
Health |
| Loewen, P.C. (2016). Crystal structure of B. pseudomallei KatG with NAD bound. Protein Data Bank: 5sxr. |
CMCF-ID |
PDB Deposition |
Health |
| Loewen, P.C. (2016). Structure of D141A variant of B. pseudomallei KatG complexed with INH. Protein Data Bank: 5syi. |
CMCF-ID |
PDB Deposition |
Health |
| Zhou, Y.F.; Wei, R.R. (2016). aSMase with zinc. Protein Data Bank: 5i8r. |
CMCF-ID |
PDB Deposition |
Health |
| Lewis, H.A.; Wu, Y.J.; Rajamani, R.; Thompson, L.A. (2016). (4~{S},6~{S})-4-[2,4-bis(fluoranyl)phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine (compound 5) bound to BACE1. Protein Data Bank: 5kr8. |
CMCF-ID |
PDB Deposition |
Health |
| Wu, Yong-Jin; Guernon, Jason; Shi, Jianliang; Marcin, Lawrence; Higgins, Mendi et al. (2016). Discovery of S3-Truncated, C-6 Heteroaryl Substituted Aminothiazine β-Site APP Cleaving Enzyme-1 (BACE1) Inhibitors. Journal of Medicinal Chemistry 59(18) , 8593-8600. 10.1021/acs.jmedchem.6b01012. [PDB: 5kr8] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Lee, Samuel K.; Shanmughapriya, Santhanam; Mok, Mac C.Y.; Dong, Zhiwei; Tomar, Dhanendra et al. (2016). Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations. Cell Chemical Biology 23(9) , 1157-1169. 10.1016/j.chembiol.2016.07.012. [PDB: 5kue, 5kug, 5kui, 5kuj] |
CMCF-ID |
Peer-Reviewed Article |
Health |