Publication Beamlines Strategic Pillar
Abbas, Yazan M.; Laudenbach, Beatrice Theres; Martínez-Montero, Saúl; Cencic, Regina; Habjan, Matthias et al. (2017). Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2′-O methylations. Proceedings of the National Academy of Sciences of the United States of America 114(11) , E2106-E2115. 10.1073/pnas.1612444114. [PDB: 5udi, 5udj, 5udk, 5udl] CMCF-ID Health
Muckelbauer, J.K. (2017). Crystal structure of Bruton agammabulinemia tyrosine kinase complexed with BMS-986142 aka (2s)-6-fluoro-5-[3-(8-fluoro-1-methyl-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-2-methylphenyl]-2-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1h-carbazole-8-carboxamide. Protein Data Bank: 5t18. CMCF-ID Health
Abbas, Y.M.; Martinez-Montero, S.; Damha, M.J.; Nagar, B. (2017). IFIT1 N216A monomeric mutant (L457E/L464E) with m7Gppp-AAAA (anti conformation of cap). Protein Data Bank: 5udl. CMCF-ID Health
Abbas, Y.M.; Martinez-Montero, S.; Damha, M.J.; Nagar, B. (2017). IFIT1 monomeric mutant (L457E/L464E) with PPP-AAAA. Protein Data Bank: 5udk. CMCF-ID Health
Abbas, Y.M.; Martinez-Montero, S.; Damha, M.J.; Nagar, B. (2017). IFIT1 monomeric mutant (L457E/L464E) with Gppp-AAAA. Protein Data Bank: 5udj. CMCF-ID Health
Abbas, Y.M.; Martinez-Montero, S.; Damha, M.J.; Nagar, B. (2017). IFIT1 monomeric mutant (L457E/L464E) with m7Gppp-AAAA (syn and anti conformations of cap). Protein Data Bank: 5udi. CMCF-ID Health
Arya, T.; Sharifahmadian, M.; Sygusch, J.; Baron, B. (2017). Conformational changes during monomer-to-dimer transition of Brucella suis VirB8. Protein Data Bank: 5jbs. CMCF-ID Health
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2017). Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4721 1-(4-fluorophenyl)-1H-imidazole. Protein Data Bank: 5ifd. CMCF-ID Health
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2017). Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-2643 5-[(4-chlorophenyl)methyl]-1,3,4-oxadiazol-2-amine. Protein Data Bank: 5if8. CMCF-ID Health
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2017). Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4720 1-(4-bromophenyl)-1H-imidazole. Protein Data Bank: 5ifc. CMCF-ID Health
Park, J.; Zielinski, M.; Tsantrizos, Y.S.; Berghuis, A.M. (2017). Crystal structure of human FPPS with allosterically bound FPP. Protein Data Bank: 5ja0. CMCF-ID Health
Park, Jaeok; Zielinski, Michal; Magder, Alexandr; Tsantrizos, Youla S.; Berghuis, Albert M. et al. (2017). Human farnesyl pyrophosphate synthase is allosterically inhibited by its own product. Nature Communications 8(1) . 10.1038/ncomms14132. [PDB: 5ja0] CMCF-ID Health
Brooks, C.L.; Movahedin, M. (2017). Crystal structure of therapeutic mAB AR20.5 in complex with MUC1 peptide. Protein Data Bank: 5t78. CMCF-ID Health
Brooks, C.L.; Movahedin, M. (2017). Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen.. Protein Data Bank: 5t6p. CMCF-ID Health
Wahba, Haytham M.; Stevenson, Michael J.; Mansour, Ahmed; Sygusch, Jurgen; Wilcox, Dean E. et al. (2017). Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon–Metal Bond Cleavage. Journal of the American Chemical Society 139(2) , 910-921. 10.1021/jacs.6b11327. [PDB: 5u79, 5u7b, 5u7c, 5u82, 5u83] CMCF-ID Health