| Berghuis, A.M.; Fong, D.H. (2017). Macrolide 2'-phosphotransferase type II. Protein Data Bank: 5igu. |
CMCF-ID |
PDB Deposition |
Health |
| Berghuis, A.M.; Fong, D.H. (2017). Macrolide 2'-phosphotransferase type I - complex with guanosine and erythromycin. Protein Data Bank: 5igt. |
CMCF-ID |
PDB Deposition |
Health |
| Berghuis, A.M.; Fong, D.H. (2017). Macrolide 2'-phosphotransferase type I - complex with guanosine and oleandomycin. Protein Data Bank: 5igs. |
CMCF-ID |
PDB Deposition |
Health |
| Berghuis, A.M.; Fong, D.H. (2017). Macrolide 2'-phosphotransferase type I - complex with GDP and oleandomycin. Protein Data Bank: 5igr. |
CMCF-ID |
PDB Deposition |
Health |
| Berghuis, A.M.; Fong, D.H. (2017). Macrolide 2'-phosphotransferase type I - complex with GDP and erythromycin. Protein Data Bank: 5igp. |
CMCF-ID |
PDB Deposition |
Health |
| Berghuis, A.M.; Fong, D.H. (2017). Macrolide 2'-phosphotransferase type I - complex with guanosine and clarithromycin. Protein Data Bank: 5igj. |
CMCF-ID |
PDB Deposition |
Health |
| Berghuis, A.M.; Fong, D.H. (2017). Macrolide 2'-phosphotransferase type I. Protein Data Bank: 5igh. |
CMCF-ID |
PDB Deposition |
Health |
| Berghuis, A.M.; Fong, D.H. (2017). Macrolide 2'-phosphotransferase type I - complex with guanosine and azithromycin. Protein Data Bank: 5igi. |
CMCF-ID |
PDB Deposition |
Health |
| Fong, Desiree H.; Burk, David L.; Blanchet, Jonathan; Yan, Amy Y.; Berghuis, Albert M. et al. (2017). Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance. Structure 25(5) , 750-761. 10.1016/j.str.2017.03.007. [PDB: 5igh, 5igi, 5igj, 5igp, 5igr, 5igs, 5igt, 5igu, 5igv, 5igy, 5igz, 5ih0, 5ih1, 5iwu] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Gajiwala, K.S.; Ferre, R.A. (2017). Crystal structure of the EGFR kinase domain (L858R, T790M, V948R) in complex with a covalent inhibitor N-[(3R,4R)-4-fluoro-1-{6-[(3-methoxy-1-methyl-1H-pyrazol-4-yl)amino]-9-methyl-9H-purin-2-yl}pyrrolidin-3-yl]propanamide. Protein Data Bank: 5ugc. |
CMCF-ID |
PDB Deposition |
Health |
| Planken, Simon; Behenna, Douglas C.; Nair, Sajiv K.; Johnson, Theodore O.; Nagata, Asako et al. (2017). Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR. Journal of Medicinal Chemistry 60(7) , 3002-3019. 10.1021/acs.jmedchem.6b01894. [PDB: 5ugc] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Gorelik, A.; Liu, F.; Illes, K.; Nagar, B. (2017). Human alkaline sphingomyelinase (alk-SMase, ENPP7, NPP7). Protein Data Bank: 5udy. |
CMCF-ID |
PDB Deposition |
Health |
| Gorelik, A.; Liu, F.; Illes, K.; Nagar, B. (2017). Human alkaline sphingomyelinase (ENPP7) in complex with phosphocholine. Protein Data Bank: 5tcd. |
CMCF-ID |
PDB Deposition |
Health |
| Gorelik, Alexei; Liu, Fangyu; Illes, Katalin; Nagar, Bhushan (2017). Crystal structure of the human alkaline sphingomyelinase provides insights into substrate recognition. Journal of Biological Chemistry 292(17) , 7087-7094. 10.1074/jbc.m116.769273. [PDB: 5tcd, 5udy] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Cook, Jonathan D.; Sultana, Azmiri; Lee, Jeffrey E. (2017). Structure of the infectious salmon anemia virus receptor complex illustrates a unique binding strategy for attachment. Proceedings of the National Academy of Sciences of the United States of America 114(14) , E2929-E2936. 10.1073/pnas.1617993114. [PDB: 5t96, 5t9y] |
CMCF-ID |
Peer-Reviewed Article |
Health |