Publication Beamlines Strategic Pillar
Gong, Hua; Weinstein, David S.; Lu, Zhonghui; Duan, James J.-W.; Stachura, Sylwia et al. (2018). Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity. Bioorganic and Medicinal Chemistry Letters 28(2) , 85-93. 10.1016/j.bmcl.2017.12.006. [PDB: 6bns] CMCF-ID Health
DHAR, T.G.; GONG, H.; WEINSTEIN, D.S.; LU, Z.; DUAN, J.J.W. et al. (2017). STRUCTURE OF HUMAN PREGNANE X RECEPTOR LIGAND BINDING DOMAIN BOUND TETHERED WITH SRC co-activator peptide and Compound 25a AKA BICYCLIC HEXAFLUOROISOPROPYL 2 ALCOHOL SULFONAMIDES. Protein Data Bank: 6bns. CMCF-ID Health
Lyons, Bronwyn; Lugo, Miguel R.; Carlin, Stephanie; Lidster, Taylor; Merrill, A. Rod et al. (2018). Characterization of the catalytic signature of Scabin toxin, a DNA-targeting ADP-ribosyltransferase. Biochemical Journal 475(1) , 225-245. 10.1042/bcj20170818. [PDB: 5tlb, 5uvq, 6apy] CMCF-ID Health
Ravulapalli, R.; Heney, K.; Ebeling, J.; Genersch, E.; Merrill, A.R. et al. (2017). Plx2a, an ADP-ribosyltransferase toxin from Paenibacillus larvae. Protein Data Bank: 5urp. CMCF-ID Health
Picard, Marie-Ève; Nisole, Audrey; Béliveau, Catherine; Sen, Stephanie; Barbar, Aline et al. (2018). Structural characterization of a lepidopteran type-II farnesyl diphosphate synthase from the spruce budworm, Choristoneura fumiferana : Implications for inhibitor design. Insect Biochemistry and Molecular Biology 92, 84-92. 10.1016/j.ibmb.2017.11.011. [PDB: 6b02, 6b04, 6b06] CMCF-ID Health
Scally, S.W.; Bosch, A.; Triller, G.; Wardemann, H.; Julien, J.P. et al. (2017). Crystal structure of the neutralizing anti-circumsporozoite protein 663 antibody. Protein Data Bank: 6azx. CMCF-ID Health
Scally, S.W.; Bosch, A.; Triller, G.; Wardemann, H.; Julien, J.P. et al. (2017). Crystal structure of the 580 germline antibody bound to circumsporozoite protein NANP 5-mer. Protein Data Bank: 6azm. CMCF-ID Health
Scally, S.W.; Bosch, A.; Triller, G.; Wardemann, H.; Julien, J.P. et al. (2017). Crystal structure of the anti-circumsporozoite protein 663 germline antibody. Protein Data Bank: 5bk5. CMCF-ID Health
Scally, S.W.; Bosch, A.; Triller, G.; Wardemann, H.; Julien, J.P. et al. (2017). Crystal structure of the neutralizing anti-circumsporozoite protein 580 antibody. Protein Data Bank: 5bk3. CMCF-ID Health
Scally, S.W.; Bosch, A.; Triller, G.; Wardemann, H.; Julien, J.P. et al. (2017). Crystal structure of 663 Fab bound to circumsporozoite protein NANP 5-mer. Protein Data Bank: 5bk0. CMCF-ID Health
Bryson, Steve; Thomson, Christy A.; Risnes, Louise F.; Dasgupta, Somnath; Smith, Kenneth et al. (2016). Structures of Preferred Human IgV Genes–Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation. Journal of Immunology 196(11) , 4723-4730. 10.4049/jimmunol.1402890. [PDB: 4hh9, 4hha] CMCF-ID Health
Wong, A.H.; Rini, J.M. (2017). Crystal structure of the human coronavirus 229E spike protein receptor binding domain in complex with human aminopeptidase N. Protein Data Bank: 6atk. CMCF-ID Health
Wong, Alan H. M.; Tomlinson, Aidan C. A.; Zhou, Dongxia; Satkunarajah, Malathy; Chen, Kevin et al. (2017). Receptor-binding loops in alphacoronavirus adaptation and evolution. Nature Communications 8(1) . 10.1038/s41467-017-01706-x. [PDB: 6atk] CMCF-ID Health
Tanaka, H.; Blaesse, M.; Augustin, M.; Goesser, C. (2017). Crystal structure of Trk-A complexed with a selective inhibitor CH7057288. Protein Data Bank: 5wr7. CMCF-ID Health
Lesburg, C.A.; Patel, S.B. (2017). JAK1 complexed with compound 28. Protein Data Bank: 5wo4. CMCF-ID Health