Planken, Simon; Behenna, Douglas C.; Nair, Sajiv K.; Johnson, Theodore O.; Nagata, Asako et al. (2017). Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR. Journal of Medicinal Chemistry 60(7) , 3002-3019. 10.1021/acs.jmedchem.6b01894. [PDB: 5ugc] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Stanger, Frédéric V.; de Beer, Tjaart A.P.; Dranow, David M.; Schirmer, Tilman; Phan, Isabelle et al. (2017). The BID Domain of Type IV Secretion Substrates Forms a Conserved Four-Helix Bundle Topped with a Hook. Structure 25(1) , 203-211. 10.1016/j.str.2016.10.010. [PDB: 4yk1] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Wahba, Haytham M.; Stevenson, Michael J.; Mansour, Ahmed; Sygusch, Jurgen; Wilcox, Dean E. et al. (2017). Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon–Metal Bond Cleavage. Journal of the American Chemical Society 139(2) , 910-921. 10.1021/jacs.6b11327. [PDB: 5u79, 5u7b, 5u7c, 5u82, 5u83] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Noach, I.; Boraston, A.B. (2017). IMPa metallopeptidase in complex with T-antigen. Protein Data Bank: 5kdx. |
CMCF-BM |
PDB Deposition |
Agriculture |
Noach, I.; Boraston, A.B. (2017). IMPa metallopeptidase from Pseudomonas aeruginosa. Protein Data Bank: 5kdv. |
CMCF-BM |
PDB Deposition |
Agriculture |
Noach, I.; Ficko-Blean, E.; Stuart, C.; Boraston, A.B. (2017). ZmpB metallopeptidase from Clostridium perfringens. Protein Data Bank: 5kdn. |
CMCF-BM |
PDB Deposition |
Agriculture |
Ulaganathan, T.S.; Boniecki, M.T.; Cygler, M. (2017). Structure of a new family of Polysaccharide lyase PL25-Ulvanlyase.. Protein Data Bank: 5uam. |
CMCF-BM |
PDB Deposition |
Agriculture |
Ulaganathan, T.S.; Cygler, M. (2017). Structure of a new family of Polysaccharide lyase PL25-Ulvanlyase bound to -[GlcA(1-4)Rha3S]-. Protein Data Bank: 5uas. |
CMCF-BM |
PDB Deposition |
Agriculture |
Worrall, L.J.; Sobhanifar, S.; King, D.T.; Strynadka, N.C. (2017). Crystal structure of S. aureus TarS 217-571. Protein Data Bank: 5u02. |
CMCF-BM |
PDB Deposition |
Health |
Noach, Ilit; Ficko-Blean, Elizabeth; Pluvinage, Benjamin; Stuart, Christopher; Jenkins, Meredith L. et al. (2017). Recognition of protein-linked glycans as a determinant of peptidase activity. Proceedings of the National Academy of Sciences of the United States of America 114(5) , E679-E688. 10.1073/pnas.1615141114. [PDB: 5kd5, 5kd8, 5kdn, 5kdu, 5kdv, 5kdw, 5kdx] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Ulaganathan, ThirumalaiSelvi; Boniecki, Michal T.; Foran, Elizabeth; Buravenkov, Vitaliy; Mizrachi, Naama et al. (2017). New Ulvan-Degrading Polysaccharide Lyase Family: Structure and Catalytic Mechanism Suggests Convergent Evolution of Active Site Architecture. ACS Chemical Biology 12(5) , 1269-1280. 10.1021/acschembio.7b00126. [PDB: 5uam, 5uas] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Hu; Jinhong (2017). Determination of the Binding Mode of Hydroxycitrate, and Investigation of the Binding Site of 14-3-3 Protein on Human ATP Citrate Lyase. Supervisor: Fraser, Marie. AB, Canada: University of Calgary. http://dx.doi.org/10.11575/PRISM/25607. |
CMCF |
Masters Thesis |
|
Katherine E. Feick (2017). An Evaluation of the Lithologies and Geochemistry of the Upper Beaver Deposit of the Kirkland Lake Area. Supervisor: Banerjee, Neil R.; Van Loon, Lisa L.. Ontario, Canada: Western University. . |
CLS-APS, VESPERS |
Masters Thesis |
Environment |
Choudhury, S.; Agyeman-Budu, D. N.; Woll, A. R.; Swanston, T.; Varney, T. L. et al. (2017). Superior spatial resolution in confocal X-ray techniques using collimating channel array optics: elemental mapping and speciation in archaeological human bone. Journal of Analytical Atomic Spectrometry 32(3) . 10.1039/c6ja00297h. |
CLS-APS |
Peer-Reviewed Article |
|
Good, Jacob; Duchesne, Paul N.; Zhang, Peng; Koshut, William; Zhou, Meng et al. (2017). On the functional role of the cerium oxide support in the Au38(SR)24/CeO2 catalyst for CO oxidation. Catalysis Today 280, 239-245. 10.1016/j.cattod.2016.04.016. |
CLS-APS |
Peer-Reviewed Article |
|