Publication Beamlines Strategic Pillar
Hedges, Jason B.; Kuatsjah, Eugene; Du, Yi-Ling; Eltis, Lindsay D.; Ryan, Katherine S. et al. (2018). Snapshots of the Catalytic Cycle of an O2, Pyridoxal Phosphate-Dependent Hydroxylase. ACS Chemical Biology 13(4) , 965-974. 10.1021/acschembio.8b00039. [PDB: 6c3a, 6c3b, 6c3c, 6c3d] CMCF-ID Health
Mahoney, Sarah J.; Narayan, Sridhar; Molz, Lisa; Berstler, Lauren A.; Kang, Seong A. et al. (2018). A small molecule inhibitor of Rheb selectively targets mTORC1 signaling. Nature Communications 9(1) . 10.1038/s41467-018-03035-z. [PDB: 6bt0] CMCF-ID Health
Leighton, T. L.; Mok, M. C.; Junop, M. S.; Howell, P. L.; Burrows, L. L. et al. (2018). Conserved, unstructured regions in Pseudomonas aeruginosa PilO are important for type IVa pilus function. Scientific Reports 8(1) . 10.1038/s41598-018-20925-w. [PDB: 5uvr] CMCF-ID Health
Ereño-Orbea, June; Sicard, Taylor; Cui, Hong; Carson, Jacob; Hermans, Pim et al. (2018). Structural Basis of Enhanced Crystallizability Induced by a Molecular Chaperone for Antibody Antigen-Binding Fragments. Journal of Molecular Biology 430(3) , 322-336. 10.1016/j.jmb.2017.12.010. [PDB: 6ana, 6and, 6ani] CMCF-ID Health
Ulaganathan, ThirumalaiSelvi; Helbert, William; Kopel, Moran; Banin, Ehud; Cygler, Miroslaw et al. (2018). Structure–function analyses of a PL24 family ulvan lyase reveal key features and suggest its catalytic mechanism. Journal of Biological Chemistry 293(11) , 4026-4036. 10.1074/jbc.ra117.001642. [PDB: 6byp, 6byt, 6byx] CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Illes, Katalin; Nagar, Bhushan (2018). Crystal structure of the mammalian lipopolysaccharide detoxifier. Proceedings of the National Academy of Sciences of the United States of America 115(5) , E896-E905. 10.1073/pnas.1719834115. [PDB: 5w78, 5w7a, 5w7b, 5w7c, 5w7d, 5w7e, 5w7f] CMCF-ID Health
Gong, Hua; Weinstein, David S.; Lu, Zhonghui; Duan, James J.-W.; Stachura, Sylwia et al. (2018). Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity. Bioorganic and Medicinal Chemistry Letters 28(2) , 85-93. 10.1016/j.bmcl.2017.12.006. [PDB: 6bns] CMCF-ID Health
Lyons, Bronwyn; Lugo, Miguel R.; Carlin, Stephanie; Lidster, Taylor; Merrill, A. Rod et al. (2018). Characterization of the catalytic signature of Scabin toxin, a DNA-targeting ADP-ribosyltransferase. Biochemical Journal 475(1) , 225-245. 10.1042/bcj20170818. [PDB: 5tlb, 5uvq, 6apy] CMCF-ID Health
Picard, Marie-Ève; Nisole, Audrey; Béliveau, Catherine; Sen, Stephanie; Barbar, Aline et al. (2018). Structural characterization of a lepidopteran type-II farnesyl diphosphate synthase from the spruce budworm, Choristoneura fumiferana : Implications for inhibitor design. Insect Biochemistry and Molecular Biology 92, 84-92. 10.1016/j.ibmb.2017.11.011. [PDB: 6b02, 6b04, 6b06] CMCF-ID Health
Sun, Luxin (2018). Involvement of BRCT Family Proteins in DNA Damage Response. Supervisor: Glover, Mark. Alberta, Canada: University of Alberta. https://doi.org/10.7939/R3CZ32K9V. CMCF-BM, CMCF-ID Health
Gorelik, Alexei (2018). Structural Study of the Acid Sphingomyelinase Protein Family. Supervisor: Nagar, Bhushan. QC, Canada: McGill University. https://escholarship.mcgill.ca/concern/theses/wp988n513. CMCF-BM, CMCF-ID Health
Hamilton, Jordan (2018). Phosphorus Speciation and Amendment Fate in Calcareous Petroleum Hydrocarbon Contaminated Soils. Supervisor: Peak, Derek. SK, Canada: University of Saskatchewan. http://hdl.handle.net/10388/8434. CMCF-BM, SXRMB, VESPERS Environment
Crowe; Adam Michael (2018). The catabolism of the last two rings of cholesterol by Mycobacterium tuberculosis. Supervisor: Eltis, Lindsay D.. BC, Canada: University of British Columbia. http://hdl.handle.net/2429/64634. CMCF-BM
Crowe, A.M.; Workman, S.D.; Watanabe, N.; Worrall, L.J.; Strynadka, N.C.J. et al. (2018). Crystal structure of Mycobacterium tuberculosis IpdAB. Protein Data Bank: 6con. CMCF-BM Health
Crowe, A.M.; Workman, S.D.; Watanabe, N.; Worrall, L.J.; Strynadka, N.C.J. et al. (2018). Crystal structure of Rhodococcus jostii RHA1 IpdAB E105A COCHEA-COA complex. Protein Data Bank: 6coj. CMCF-BM Health