Publication Beamlines Strategic Pillar
Goedken, Eric R.; Argiriadi, Maria A.; Dietrich, Justin D.; Petros, Andrew M.; Krishnan, Navasona et al. (2022). Identification and structure-based drug design of cell-active inhibitors of interleukin 17A at a novel C-terminal site. Scientific Reports 12(1) . 10.1038/s41598-022-18760-1. [PDB: 8dyg] CMCF-ID Health
Taylor, Alexander M.; Bailey, Chris; Belmont, Lisa D.; Campbell, Robert; Cantone, Nico et al. (2022). GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1. Journal of Medicinal Chemistry 65(16) , 11177-11186. 10.1021/acs.jmedchem.2c00662. [PDB: 7td9] CMCF-ID Health
Kozlov, Guennadi; Mattijssen, Sandy; Jiang, Jianning; Nyandwi, Samuel; Sprules, Tara et al. (2022). Structural basis of 3′-end poly(A) RNA recognition by LARP1. Nucleic Acids Research 50(16) , 9534-9547. 10.1093/nar/gkac696. [PDB: 7soo, 7sop] CMCF-ID Health
Wilding, Birgit; Scharn, Dirk; Böse, Dietrich; Baum, Anke; Santoro, Valeria et al. (2022). Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling. Nature Cancer 3(7) , 821-836. 10.1038/s43018-022-00412-y. [PDB: 7pcd] CMCF-ID Health
Nguyen, Peter; Eshaque, Rony; Garland, Barbara Anne; Dang, Anthony; Suits, Michael D. L. et al. (2022). Degradation of chondroitin sulfate A by a PUL-like operon in Tannerella forsythia. PLoS ONE 17(9) , e0272904. 10.1371/journal.pone.0272904. [PDB: 8di0, 8di1] CMCF-BM, CMCF-ID Health
Itai Sharon (2022). Structural insights into the biosynthesis and biodegradation of cyanophycin. Supervisor: Schmeing, Thomas Martin. Quebec, Canada: McGill University. https://escholarship.mcgill.ca/concern/theses/5712md34f. CMCF-BM Health
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2022). Crystal Structure of UDP-N-acetylmuramate-L-alanine ligase (UDP-N-acetylmuramoyl-L-alanine synthetase, MurC) Pseudomonas aeruginosa in complex with ligand AZ-13643701. Protein Data Bank: 8egn. CMCF-BM Agriculture
Lee, J.; Kenward, C.; Worrall, L.J.; Vuckovic, M.; Paetzel, M. et al. (2022). Structure of SARS-CoV-2 Mpro in complex with nsp12-nsp13 (C12) cut site sequence. Protein Data Bank: 8ds1. CMCF-BM Health
Lee, J.; Kenward, C.; Worrall, L.J.; Vuckovic, M.; Paetzel, M. et al. (2022). Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp10-nsp11 (C10) cut site sequence (form 2). Protein Data Bank: 8drx. CMCF-BM Health
Lee, J.; Kenward, C.; Worrall, L.J.; Vuckovic, M.; Paetzel, M. et al. (2022). Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp7-nsp8 (C7) cut site sequence. Protein Data Bank: 8dru. CMCF-BM Health
Suits, M.D.L. (2022). Bfo2290: Tannerella forsythia chondroitin sulfate A sulfatase. Protein Data Bank: 8di0. CMCF-BM Agriculture
Abraham, N.; Schroeter, K.L.; Kimber, M.S.; Seah, S.Y.K. (2022). Structure-Function characterization of an aldo-keto reductase involved in detoxification of the mycotoxin, deoxynivalenol. Protein Data Bank: 7utf. CMCF-BM Agriculture
Sharon, I.; Schmeing, T.M. (2022). Pseudobacteroides cellulosolvens pseudo-CphB. Protein Data Bank: 7uqv. CMCF-BM Agriculture
Chung, I.Y.W.; Cygler, M. (2022). Structural study of Legionella pneumophila effector DotY (Lpg0294). Protein Data Bank: 7ups. CMCF-BM Agriculture
Chan, A.C.; Kolesnikov, M.; Murphy, M.E. (2022). Arginase Domain of Ornithine Decarboxylase/Arginase from Fusobacterium nucleatum. Protein Data Bank: 8d27. CMCF-BM Agriculture