| Ketcham, John M.; Harwood, Stephen J.; Aranda, Ruth; Aloiau, Athenea N.; Bobek, Briana M. et al. (2024). Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c00078. [PDB: 8v8h] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Joan Seoane Suarez; Judit Anido Folgueira; Johan Fransson; Jean-Philippe Julien; Swetha RAMAN et al. (2024). ANTIBODIES TO LIF AND THEIR USES. Patent Number: LT3555132T. |
CMCF-ID |
Patent |
Health |
| Hughes, M.P.; Taylor, J.P. (2024). Crystal Structure of the G3BP1 NTF2-like domain bound to the Caprin1 peptide. Protein Data Bank: 8th7. |
CMCF-ID |
PDB Deposition |
Health |
| Holden, J.K.; Partridge, J.R.; Wibowo, A.S.; Mulichak, A. (2024). Ubiquitin variant i53 mutant L67R bound to 53BP1 Tudor Domain. Protein Data Bank: 8svh. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Holden, J.K.; Partridge, J.R.; Wibowo, A.S.; Mulichak, A. (2024). Ubiquitin variant i53 in complex with 53BP1 Tudor domain. Protein Data Bank: 8svg. |
CMCF-ID |
PDB Deposition |
Agriculture |
| He, Liqi; Zhang, Meng Yao; Cox, Matthew; Zhang, Qian; Donnell, Andrew F. et al. (2024). Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology. ACS Medicinal Chemistry Letters 15(2) , 189-196. 10.1021/acsmedchemlett.3c00456. [PDB: 8s9h] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Gunn, R.J.; Lawson, J.D.; Ivetac, A.; Ulaganathan, T.; Coulombe, R. et al. (2024). SOS2 crystal structure with fragment bound (compound 14). Protein Data Bank: 8t5m. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Gunn, R.J.; Lawson, J.D.; Ivetac, A.; Ulaganathan, T.; Coulombe, R. et al. (2024). SOS2 co-crystal structure with fragment bound (compound 12). Protein Data Bank: 8t5g. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Gunn, R.J.; Lawson, J.D. (2024). PI3Ka H1047R co-crystal structure with inhibitor in cryptic pocket near H1047R (compound 4).. Protein Data Bank: 8v8h. |
CMCF-ID |
PDB Deposition |
Health |
| Fraser, B.J.; Dong, A.; Ilyassov, O.; Kenney, T.; Li, Y.Y. et al. (2024). Human TMPRSS11D complexed with a disulfide-linked autoinhibitory DDDDK peptide. Protein Data Bank: 8vis. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Folger, Ines B.; Frota, Natália F.; Pistofidis, Angelos; Niquille, David L.; Hansen, Douglas A. et al. (2024). High-throughput reprogramming of an NRPS condensation domain. Nature Chemical Biology . 10.1038/s41589-023-01532-x. [PDB: 8f7f] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Dhindwal, P.; Ruzzini, A. (2024). Bile salt hydrolase from Arthrobacter citreus with covalent inhibitor AAA-10 bound. Protein Data Bank: 8vsy. |
CMCF-ID |
PDB Deposition |
Health |
| Dementiev, A.A.; Michino, M.; Vendome, J.; Ginn, J.; Bryk, R. et al. (2024). Co-crystal structure of optimized analog TDI-13537 provided new insights into the potency determinants of the sulfonamide inhibitor series. Protein Data Bank: 8u0q. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Daniel-Ivad, Phillip; Ryan, Katherine S. (2024). An imine reductase that captures reactive intermediates in the biosynthesis of the indolocarbazole reductasporine. Journal of Biological Chemistry , 105642. 10.1016/j.jbc.2024.105642. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Critton, D.A. (2024). Crystal structure of monkey TLR7 ectodomain with compound 14. Protein Data Bank: 8s9h. |
CMCF-ID |
PDB Deposition |
Health |