| Riggs, Jennifer R.; Nagy, Mark; Elsner, Jan; Erdman, Paul; Cashion, Dan et al. (2017). The Discovery of a Dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) Inhibitor for the Treatment of Triple Negative Breast Cancer Initiated from a Phenotypic Screen. Journal of Medicinal Chemistry 60(21) , 8989-9002. 10.1021/acs.jmedchem.7b01223. [PDB: 6b4w] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Ravulapalli, R.; Heney, K.; Ebeling, J.; Genersch, E.; Merrill, A.R. et al. (2017). Plx2a, an ADP-ribosyltransferase toxin from Paenibacillus larvae. Protein Data Bank: 5urp. |
CMCF-ID |
PDB Deposition |
Health |
| Rai, Ganesha; Brimacombe, Kyle R.; Mott, Bryan T.; Urban, Daniel J.; Hu, Xin et al. (2017). Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH). Journal of Medicinal Chemistry 60(22) , 9184-9204. 10.1021/acs.jmedchem.7b00941. [PDB: 5w8h, 5w8j] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Picard, M.-E.; Cusson, M.; Shi, R. (2017). Crystal structure of CfFPPS2, a lepidopteran type-II farnesyl diphosphate synthase, complexed with IPP and [2-(1-methylpyridin-2-yl)-1-phosphono-ethyl]phosphonic acid (inhibitor 1b). Protein Data Bank: 6b06. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Picard, M.-E.; Cusson, M.; Shi, R. (2017). Crystal structure of CfFPPS2, a lepidopteran type-II farnesyl diphosphate synthase, complexed with [2-(1-methylpyridin-2-yl)-1-phosphono-ethyl]phosphonic acid (inhibitor 1b). Protein Data Bank: 6b04. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Picard, M.-E.; Cusson, M.; Shi, R. (2017). Crystal structure of CfFPPS2 (apo form), a lepidopteran type-II farnesyl diphosphate synthase. Protein Data Bank: 6b02. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Park, Jaeok; Rodionov, Dmitry; De Schutter, Joris W.; Lin, Yih-Shyan; Tsantrizos, Youla S. et al. (2017). Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase. PLoS ONE 12(10) , e0186447. 10.1371/journal.pone.0186447. [PDB: 4nfi, 4nfj, 4nfk] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Min, X.; Wang, Z. (2017). Crystal structure of growth differentiation factor. Protein Data Bank: 5vt2. |
CMCF-ID |
PDB Deposition |
Health |
| McLeod, B.; Scally, S.W.; Bosch, A.; King, C.R.; Julien, J.P. et al. (2017). Crystal structure of Pfs25 in complex with the transmission blocking antibody 1262. Protein Data Bank: 6b0h. |
CMCF-ID |
PDB Deposition |
Health |
| McLeod, B.; Scally, S.W.; Bosch, A.; King, C.R.; Julien, J.P. et al. (2017). Crystal structure of Pfs25 in complex with the transmission blocking antibody 1245. Protein Data Bank: 6b0g. |
CMCF-ID |
PDB Deposition |
Health |
| Lyons, B.; Lidster, T.; Merrill, A.R. (2017). Scabin (W128Y) toxin from Streptomyces scabies. Protein Data Bank: 6apy. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Lyons, B.; Lidster, T.; Merrill, A.R. (2017). Scabin (W155A) toxin from Streptomyces scabies. Protein Data Bank: 5uvq. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Lyons, B.; Dutta, D.; Ravulapalli, R.; Merrill, A.R. (2017). Scabin toxin from Streptomyces scabies in complex with NADH. Protein Data Bank: 5tlb. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Liu, K.; Xu, C.; Tempel, W.; Walker, J.R.; Arrowsmith, C.H. et al. (2017). Zinc finger region of MBD1 in complex with CpG DNA. Protein Data Bank: 5w9q. |
CMCF-ID |
PDB Deposition |
Health |
| Lesburg, C.A.; Patel, S.B. (2017). JAK1 complexed with compound 28. Protein Data Bank: 5wo4. |
CMCF-ID |
PDB Deposition |
Health |