Publication Beamlines Strategic Pillar
Wahba, H.M.; Stevenson, M.; Mansour, A.; Sygusch, J.; Wilcox, D.E. et al. (2017). Crystal structure of a complex formed between MerB and Dimethyltin. Protein Data Bank: 5u79. CMCF-ID Agriculture
Wahba, Haytham M.; Stevenson, Michael J.; Mansour, Ahmed; Sygusch, Jurgen; Wilcox, Dean E. et al. (2017). Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon–Metal Bond Cleavage. Journal of the American Chemical Society 139(2) , 910-921. 10.1021/jacs.6b11327. [PDB: 5u79, 5u7b, 5u7c, 5u82, 5u83] CMCF-ID Health
Tempel, W.; Yu, W.; Dong, A.; Cerovina, T.; Bountra, C. et al. (2017). Methyltransferase domain of human Wolf-Hirschhorn Syndrome Candidate 1-Like protein 1 (WHSC1L1). Protein Data Bank: 5upd. CMCF-ID
Stanger, Frédéric V.; de Beer, Tjaart A.P.; Dranow, David M.; Schirmer, Tilman; Phan, Isabelle et al. (2017). The BID Domain of Type IV Secretion Substrates Forms a Conserved Four-Helix Bundle Topped with a Hook. Structure 25(1) , 203-211. 10.1016/j.str.2016.10.010. [PDB: 4yk1] CMCF-ID Health
Sheriff, S. (2017). CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA- DEPENDENT RNA POLYMERASE IN COMPLEX WITH 5-[3-(tert-butylcarbamoyl)phenyl]-6-(ethylamino)-2-(4-fluorophenyl)-N-methylfuro[2,3-b]pyridine-3-carboxamide. Protein Data Bank: 5twn. CMCF-ID Agriculture
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2017). Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA. Protein Data Bank: 5ifb. CMCF-ID
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2017). Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4721 1-(4-fluorophenyl)-1H-imidazole. Protein Data Bank: 5ifd. CMCF-ID Health
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2017). Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-2643 5-[(4-chlorophenyl)methyl]-1,3,4-oxadiazol-2-amine. Protein Data Bank: 5if8. CMCF-ID Health
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2017). Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4720 1-(4-bromophenyl)-1H-imidazole. Protein Data Bank: 5ifc. CMCF-ID Health
Randriamihaja, Antsa (2017). Structural analyses of the ecto-nucleotides pyrophosphatases/phosphodiesterases 3 and 5. Supervisor: Nagar, Bhushan. QC, Canada: McGill University. https://escholarship.mcgill.ca/concern/theses/td96k517j. CMCF-ID Health
Radka; Christopher D. (2017). Structure/Function Studies of Yersinia pestis Metal Transport Systems. Supervisor: Aller, Stephen G.; DeLucas, Lawrence J.. Alabama, USA: University of Alabama at Birmingham. https://uab.primo.exlibrisgroup.com/permalink/01AL_UALB/5cjhn9/alma991002054550203176. CMCF-ID Agriculture
Planken, Simon; Behenna, Douglas C.; Nair, Sajiv K.; Johnson, Theodore O.; Nagata, Asako et al. (2017). Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR. Journal of Medicinal Chemistry 60(7) , 3002-3019. 10.1021/acs.jmedchem.6b01894. [PDB: 5ugc] CMCF-ID Health
Picard, M.-E.; Barma, J.; Shi, R. (2017). Crystal structure of CrmK, a flavoenzyme involved in the shunt product recycling mechanism in caerulomycin biosynthesis. Protein Data Bank: 5i1w. CMCF-ID Agriculture
Picard, M.-E.; Barma, J.; Shi, R. (2017). Crystal structure of CrmK, a flavoenzyme involved in the shunt product recycling mechanism in caerulomycin biosynthesis. Protein Data Bank: 5i1v. CMCF-ID Agriculture
Park, J.; Zielinski, M.; Tsantrizos, Y.S.; Berghuis, A.M. (2017). Crystal structure of human FPPS with allosterically bound FPP. Protein Data Bank: 5ja0. CMCF-ID Health