Bryson, Steve; Thomson, Christy A.; Risnes, Louise F.; Dasgupta, Somnath; Smith, Kenneth et al. (2016). Structures of Preferred Human IgV Genes–Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation. Journal of Immunology 196(11) , 4723-4730. 10.4049/jimmunol.1402890. [PDB: 4hh9, 4hha] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Blake, James F.; Burkard, Michael; Chan, Jocelyn; Chen, Huifen; Chou, Kang-Jye et al. (2016). Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development. Journal of Medicinal Chemistry 59(12) , 5650-5660. 10.1021/acs.jmedchem.6b00389. [PDB: 5k4i] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Hughes, S.J.; Antoshchenko, T.; Song, J.H.; Pizarro, J.; Park, H.W. et al. (2016). Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with 7-deaza-ATP. Protein Data Bank: 5exw. |
CMCF-ID |
PDB Deposition |
Health |
Hughes, S.J.; Antoshchenko, T.; Song, J.H.; Pizarro, J.; Park, H.W. et al. (2016). Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with AMP-PCP. Protein Data Bank: 5f2r. |
CMCF-ID |
PDB Deposition |
Health |
Hughes, S.J.; Antoshchenko, T.; Song, J.H.; Pizarro, J.; Park, H.W. et al. (2016). Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with 7-deaza-ADP and inorganic phosphate. Protein Data Bank: 5ex5. |
CMCF-ID |
PDB Deposition |
Health |
Hughes, S.J.; Antoshchenko, T.; Song, J.H.; Pizarro, J.; Park, H.W. et al. (2016). Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with ADP and inorganic phosphate. Protein Data Bank: 5evz. |
CMCF-ID |
PDB Deposition |
Health |
Hughes, S.J.; Antoshchenko, T.; Song, J.H.; Pizarro, J.; Park, H.W. et al. (2016). Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with 2'-deoxy-ADP and inorganic phosphate. Protein Data Bank: 5f0x. |
CMCF-ID |
PDB Deposition |
Health |
Hughes, Scott J.; Antoshchenko, Tetyana; Chen, Yun; Lu, Hua; Pizarro, Juan C. et al. (2016). Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs. PLoS ONE 11(5) , e0154862. 10.1371/journal.pone.0154862. [PDB: 5evz, 5ex5, 5exw, 5f0x, 5f2r] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Aydin, H.; Sultana, A.; Lee, J.E. (2016). Crystal structure of the human sperm Izumo1 residues 22-254. Protein Data Bank: 5f4t. |
CMCF-ID |
PDB Deposition |
Health |
Aydin, H.; Sultana, A.; Lee, J.E. (2016). Crystal structure of the human sperm Izumo1 and egg Juno complex. Protein Data Bank: 5f4e. |
CMCF-ID |
PDB Deposition |
Health |
Aydin, H.; Sultana, A.; Lee, J.E. (2016). Crystal structure of the human sperm Izumo1 residues 22-268. Protein Data Bank: 5f4v. |
CMCF-ID |
PDB Deposition |
Health |
Aydin, Halil; Sultana, Azmiri; Li, Sheng; Thavalingam, Annoj; Lee, Jeffrey E. et al. (2016). Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex. Nature 534(7608) , 562-565. 10.1038/nature18595. [PDB: 5f4e, 5f4t, 5f4v] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Tang, Y.; Poy, F.; Bellon, S.F. (2016). TAF1(2) bound to a pyrrolopyridone compound. Protein Data Bank: 5i29. |
CMCF-ID |
PDB Deposition |
Agriculture |
Crawford, Terry D.; Tsui, Vickie; Flynn, E. Megan; Wang, Shumei; Taylor, Alexander M. et al. (2016). Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains. Journal of Medicinal Chemistry 59(11) , 5391-5402. 10.1021/acs.jmedchem.6b00264. [PDB: 5i29] |
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Peer-Reviewed Article |
Health |
McTigue, M.; Deng, Y.; Liu, W.; Brooun, A.; Stewart, A. et al. (2016). Structure of C1156Y Mutant Human Anaplastic Lymphoma Kinase in Complex with Crizotinib. Protein Data Bank: 5aac. |
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Health |