McTigue, M.; Deng, Y.-L.; Liu, W.; Brooun, A.; Stewart, A. et al. (2016). Structure of C1156Y Mutant Human Anaplastic Lymphoma Kinase in Complex with PF-06463922 ((10R)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile).. Protein Data Bank: 5a9u. |
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McTigue, M.; Deng, Y.; Liu, W.; Brooun, A.; Stewart, A. et al. (2016). Structure of C1156Y Mutant Human Anaplastic Lymphoma Kinase in Complex with Crizotinib. Protein Data Bank: 5aac. |
CMCF-ID |
PDB Deposition |
Health |
McTigue, M.; Deng, Y.; Liu, W.; Brooun, A.; Stewart, A. et al. (2013). Structure of Human ROS1 Kinase Domain in Complex with Crizotinib. Protein Data Bank: 3zbf. |
CMCF-ID |
PDB Deposition |
Health |
McTigue, M.A.; Deng, Y.L.; Liu, W.; Brooun, A.; Stewart, A.E. et al. (2014). Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor (5R)-8-amino-3-fluoro-5,19-dimethyl-20-oxo-5,18,19,20- tetrahydro-7,11-(azeno)pyrido(2',1':2,3)imidazo(4,5-h)(2,5,11) benzoxadiazacyclotetradecine-14-carbonitrile. Protein Data Bank: 4ctb. |
CMCF-ID |
PDB Deposition |
Health |
McPhail, Jacob A.; Ottosen, Erik H.; Jenkins, Meredith L.; Burke, John E. (2017). The Molecular Basis of Aichi Virus 3A Protein Activation of Phosphatidylinositol 4 Kinase IIIβ, PI4KB, through ACBD3. Structure 25(1) , 121-131. 10.1016/j.str.2016.11.016. [PDB: 5tdq] |
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Peer-Reviewed Article |
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McPhail, J.A.; Burke, J.E. (2016). Crystal Structure of the GOLD domain of ACBD3. Protein Data Bank: 5tdq. |
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PDB Deposition |
Health |
Mcleod, M.J.; Holyoak, T. (2019). The structure of rat cytosolic PEPCK in complex with 3-(carboxymethylthiol)-picolinic acid. Protein Data Bank: 6p5o. |
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PDB Deposition |
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McLeod, Matthew J.; Tran, Norman; McCluskey, Gregory D.; Gillis, Tom D.; Bearne, Stephen L. et al. (2023). A metal‐dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine‐5′‐triphosphate. Protein Science 32(6) . 10.1002/pro.4648. [PDB: 8fv6, 8fv7, 8fv8, 8fv9, 8fva, 8fvb] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Mcleod, Matthew J.; Krismanich, Anthony P.; Assoud, Abdeljalil; Dmitrienko, Gary I.; Holyoak, Todd et al. (2019). Characterization of 3-[(Carboxymethyl)thio]picolinic Acid: A Novel Inhibitor of Phosphoenolpyruvate Carboxykinase. Biochemistry 58(37) , 3918-3926. 10.1021/acs.biochem.9b00583. [PDB: 6p5o] |
CMCF-ID |
Peer-Reviewed Article |
Health |
McLeod, Matthew J.; Holyoak, Todd (2023). Biochemical, structural, and kinetic characterization of PPi‐dependent phosphoenolpyruvate carboxykinase from Propionibacterium freudenreichii. Proteins: Structure. Function and Bioinformatics . 10.1002/prot.26513. [PDB: 8e1u] |
CMCF-BM |
Peer-Reviewed Article |
Health |
McLeod; Matthew (2020). Functional consequences of changing structure, dynamics, and free-energy landscapes of phosphoenolpyruvate carboxykinases. Supervisor: Holyoak, T.. Ontario, Canada: University of Waterloo. http://hdl.handle.net/10012/16332. |
CMCF-BM |
Doctoral Thesis |
Health |
McLeod, B.; Scally, S.W.; Bosch, A.; King, C.R.; Julien, J.P. et al. (2017). Crystal structure of Pfs25 in complex with the transmission blocking antibody 1262. Protein Data Bank: 6b0h. |
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PDB Deposition |
Health |
McLeod, B.; Scally, S.W.; Bosch, A.; King, C.R.; Julien, J.P. et al. (2017). Crystal structure of Pfs25 in complex with the transmission blocking antibody 1245. Protein Data Bank: 6b0g. |
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PDB Deposition |
Health |
McLeod, B.R.; Julien, J.P. (2019). Pfs25 in complex with the human transmission blocking antibody 2586. Protein Data Bank: 6phd. |
CMCF-ID |
PDB Deposition |
Health |
McLeod, B.R.; Julien, J.P. (2019). Pfs25 in complex with the human transmission blocking antibody 2530. Protein Data Bank: 6phb. |
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PDB Deposition |
Health |