Publication Beamlines Strategic Pillar
Mellor, Paul; Marshall, Jeremy D. S.; Ruan, Xuan; Whitecross, Dielle E.; Ross, Rebecca L. et al. (2018). Patient-derived mutations within the N-terminal domains of p85α impact PTEN or Rab5 binding and regulation. Scientific Reports 8(1) . 10.1038/s41598-018-25487-5. [PDB: 6d81, 6d82, 6d85, 6d86, 6d87] CMCF-BM, CMCF-ID Health
Gebai, Ahmad; Gorelik, Alexei; Li, Zixian; Illes, Katalin; Nagar, Bhushan et al. (2018). Structural basis for the activation of acid ceramidase. Nature Communications 9(1) . 10.1038/s41467-018-03844-2. [PDB: 5u7z, 5u81, 5u84] CMCF-BM, CMCF-ID Health
Jacques, Benoit; Coinçon, Mathieu; Sygusch, Jurgen (2018). Active site remodeling during the catalytic cycle in metal-dependent fructose-1,6-bisphosphate aldolases. Journal of Biological Chemistry 293(20) , 7737-7753. 10.1074/jbc.ra117.001098. [PDB: 5ucn, 5ucp, 5ucs, 5ucz, 5ud0, 5ud1, 5ud2] CMCF-BM, CMCF-ID Health
Baral, Pravas Kumar; Swayampakula, Mridula; Aguzzi, Adriano; James, Michael N. G. (2018). Structural characterization of POM 6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion. FEBS Journal 285(9) , 1701-1714. 10.1111/febs.14438. [PDB: 6aq7] CMCF-BM Health
Crowe, Adam M.; Workman, Sean D.; Watanabe, Nobuhiko; Worrall, Liam J.; Strynadka, Natalie C. J. et al. (2018). IpdAB, a virulence factor in Mycobacterium tuberculosis , is a cholesterol ring-cleaving hydrolase. Proceedings of the National Academy of Sciences of the United States of America 115(15) , E3378-E3387. 10.1073/pnas.1717015115. [PDB: 6co6, 6co9, 6coj, 6con] CMCF-BM Health
Pluvinage, Benjamin; Grondin, Julie M.; Amundsen, Carolyn; Klassen, Leeann; Moote, Paul E. et al. (2018). Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont. Nature Communications 9(1) . 10.1038/s41467-018-03366-x. [PDB: 5t9a, 5t9x, 5ta0, 5ta1, 5ta5, 5ta7, 5ta9] CMCF-BM, CMCF-ID Health