Publication Beamlines Strategic Pillar
He, Liqi; Zhang, Meng Yao; Cox, Matthew; Zhang, Qian; Donnell, Andrew F. et al. (2024). Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology. ACS Medicinal Chemistry Letters 15(2) , 189-196. 10.1021/acsmedchemlett.3c00456. [PDB: 8s9h] CMCF-ID Health
Hsiao, Yi-Chun; Wallweber, Heidi Ackerly; Alberstein, Robert G.; Lin, Zhonghua; Du, Changchun et al. (2024). Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining. Nature Communications 15(1) . 10.1038/s41467-024-52442-y. [PDB: 8t59] CMCF-ID Health
Ide, Danilo; Gorelik, Alexei; Illes, Katalin; Nagar, Bhushan (2024). Structural Analysis of Mammalian Sialic Acid Esterase. Journal of Molecular Biology 436(22) , 168801. 10.1016/j.jmb.2024.168801. [PDB: 8f9o] CMCF-ID Health
Ireland, Kendra A.; Kayrouz, Chase M.; Abbott, Marissa L.; Seyedsayamdost, Mohammad R.; Davis, Katherine M. et al. (2024). Structural insights into the convergent evolution of sulfoxide synthase EgtB-IV, an ergothioneine-biosynthetic homolog of ovothiol synthase OvoA. Structure . 10.1016/j.str.2024.08.006. [PDB: 8vig, 8vih] CMCF-ID Health
Kaasalainen, Martti; Zhang, Ran; Vashisth, Priya; Birjandi, Anahid Ahmadi; S’Ari, Mark et al. (2024). Lithiated porous silicon nanowires stimulate periodontal regeneration. Nature Communications 15(1) . 10.1038/s41467-023-44581-5. VLS-PGM Health
Kaduk, James A.; Dosen, Anja; Blanton, Thomas N. (2024). Crystal structure of racemic benserazide hydrochloride Form I, C10H16N3O5Cl. Powder Diffraction , 1-7. 10.1017/s0885715624000496. BXDS-WLE Health
Kaduk, James A.; Dosen, Anja; Blanton, Thomas N. (2024). Crystal structure of gepirone, C19H29N5O2. Powder Diffraction , 1-6. 10.1017/s0885715624000514. BXDS-WLE Health
Kalugin, Denis; Bahig, Jumanah; Shoker, Ahmed; Doan, Huu; Kirychuk, Shelley et al. (2024). Superhydrophobic polyether sulfone (PES) dialysis membrane with enhanced hemocompatibility and reduced human serum protein interactions: Ex vivo, in situ synchrotron imaging, experimental, and computational studies. Separation and Purification Technology 335, 126071. 10.1016/j.seppur.2023.126071. BMIT-BM Health
Kassardjian, Audrey; Ivanochko, Danton; Barber, Brian; Jetha, Arif; Julien, Jean-Philippe et al. (2024). Humanization of Pan-HLA-DR mAb 44H10 Hinges on Critical Residues in the Antibody Framework. Antibodies 13(3) , 57. 10.3390/antib13030057. [PDB: 9b7b] CMCF-ID Health
Ketcham, John M.; Harwood, Stephen J.; Aranda, Ruth; Aloiau, Athenea N.; Bobek, Briana M. et al. (2024). Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c00078. [PDB: 8v8h] CMCF-ID Health
Kozlov, Guennadi; Jiang, Jianning; Rutherford, Tyler; Noronha, Anne M.; Wilds, Christopher J. et al. (2024). Enhanced binding of guanylated poly(A) RNA by the LaM domain of LARP1. RNA Biology 21(1) , 764-773. 10.1080/15476286.2024.2379121. CMCF-ID Health
Kwon, Min Chul; Thuring, Jan Willem; Querolle, Olivier; Dai, Xuedong; Verhulst, Tinne et al. (2024). Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A- and NPM1-altered leukemias. Blood 144(11) , 1206-1220. 10.1182/blood.2023022480. [PDB: 9z4x] CMCF-ID Health
Lamontagne, Halynne R.; Cranston, Rosemary R.; Comeau, Zachary J.; Harris, Cory S.; Shuhendler, Adam J. et al. (2024). Axial Phenoxylation of Aluminum Phthalocyanines for Improved Cannabinoid Sensitivity in OTFT Sensors. Advanced Science 11(27) . 10.1002/advs.202305515. BXDS-IVU Health
Langelier, Marie-France; Mirhasan, Manija; Gilbert, Karine; Sverzhinksy, Aleksandr; Furtos, Alexandra et al. (2024). PARP enzyme de novo synthesis of protein-free poly(ADP-ribose). Molecular Cell 84(24) , 4758-4773.e6. 10.1016/j.molcel.2024.10.024. [PDB: 9bpy, 9dmc] CMCF-BM Health
Legare, Scott; Heide, Fabian; Gabir, Haben; Rafiei, Faride; Meier, Markus et al. (2024). Identifying the molecular basis of Laminin N-terminal domain Ca2+ binding using a hybrid approach. Biophysical Journal 123(16) , 2422-2430. 10.1016/j.bpj.2024.06.005. CMCF-ID Health