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Pérez-Vargas, Jimena; Worrall, Liam J.; Olmstead, Andrea D.; Ton, Anh-Tien; Lee, Jaeyong et al. (2023). A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerging Microbes and Infections 12(2) . 10.1080/22221751.2023.2246594. [PDB: 8cyu, 8cyz, 8sxr] |
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Richardson-Sanchez, Tomas; Chan, Anson C. K.; Sabatino, Brendil; Lin, Helen; Gaynor, Erin C. et al. (2023). Dissecting components of theCampylobacter jejuni fetMP-fetABCDEFgene cluster in iron scavenging. Tribology Letters . 10.1101/2023.07.05.547857. [PDB: 8t4c] |
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Rolando, Monica; Wah Chung, Ivy Yeuk; Xu, Caishuang; Gomez-Valero, Laura; England, Patrick et al. (2023). The SET and ankyrin domains of the secreted
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Sadaati, Shaghayegh; Daneshamouz, Sana; Bahig, Jumanah; Shoker, Ahmed; Abdelrasoul, Amira et al. (2023). In-Situ Synchrotron Imaging, Experimental, and Computational Investigations on the Efficiency of Trametes versicolor Laccase on Detoxification of P-Cresyl Sulfate (PCS) Protein Bound Uremic Toxin (PBUT). Journal of Biotechnology 368, 12-30. 10.1016/j.jbiotec.2023.03.011. |
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Sharon, Itai; McKay, Geoffrey A.; Nguyen, Dao; Schmeing, T. Martin (2023). Discovery of cyanophycin dipeptide hydrolase enzymes suggests widespread utility of the natural biopolymer cyanophycin. Proceedings of the National Academy of Sciences of the United States of America 120(8) . 10.1073/pnas.2216547120. |
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Sharon, Itai; Schmeing, T. Martin (2023). Bioinformatics of cyanophycin metabolism genes and characterization of promiscuous isoaspartyl dipeptidases that catalyze the final step of cyanophycin degradation. Scientific Reports 13(1) . 10.1038/s41598-023-34587-w. |
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Shen, Yi; Wen, Yurong; Sposini, Silvia; Vishwanath, Anjali Amrapali; Abdelfattah, Ahmed S. et al. (2023). Rational Engineering of an Improved Genetically Encoded pH Sensor Based on Superecliptic pHluorin. ACS Sensors . 10.1021/acssensors.3c00484. [PDB: 7yv3, 7yv5] |
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Sishi, Zhu; Bahig, Jumanah; Kalugin, Denis; Shoker, Ahmed; Zhu, Ning et al. (2023). Influence of clinical hemodialysis membrane morphology and chemistry on protein adsorption and inflammatory biomarkers released: In-situ synchrotron imaging, clinical and computational studies. Biomedical Engineering Advances 5, 100070. 10.1016/j.bea.2022.100070. |
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Smith, Christopher R.; Chen, Dan; Christensen, James G.; Coulombe, René; Féthière, James et al. (2023). Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography. Journal of Medicinal Chemistry 67(1) , 774-781. 10.1021/acs.jmedchem.3c02140. [PDB: 8t5g, 8t5m, 8t5r] |
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Tokareva, Olena S.; Li, Kunhua; Travaline, Tara L.; Thomson, Ty M.; Swiecicki, Jean-Marie et al. (2023). Recognition and reprogramming of E3 ubiquitin ligase surfaces by α-helical peptides. Nature Communications 14(1) . 10.1038/s41467-023-42395-z. [PDB: 8ei4] |
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Varkaris, Andreas; Pazolli, Ermira; Gunaydin, Hakan; Wang, Qi; Pierce, Levi et al. (2023). Discovery and clinical proof-of-concept of RLY-2608, a first-in-class mutant-selective allosteric PI3Ka inhibitor that decouples anti-tumor activity from hyperinsulinemia. Cancer Discovery . 10.1158/2159-8290.cd-23-0944. [PDB: 8ts7] |
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