Publication Beamlines Strategic Pillar
Juvvadi, Praveen R.; Fox, David; Bobay, Benjamin G.; Hoy, Michael J.; Gobeil, Sophie M. C. et al. (2019). Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents. Nature Communications 10(1) . 10.1038/s41467-019-12199-1. [PDB: 6tz7] CMCF-ID Health
Khan, Nimra; Pelletier, Dylan; Veyron, Simon; Croteau, Nathalie; Ichikawa, Muneyoshi et al. (2019). Crystal structure of human PACRG in complex with MEIG1. FEMS Microbiology Ecology . 10.1101/783373. [PDB: 6ndu, 6ucc] CMCF-ID Health
Kuatsjah, Eugene; Verstraete, Meghan M.; Kobylarz, Marek J.; Liu, Alvin K.N.; Murphy, Michael E.P. et al. (2019). Identification of functionally important residues and structural features in a bacterial lignostilbene dioxygenase. Journal of Biological Chemistry 294(35) , jbc.RA119.009428. 10.1074/jbc.ra119.009428. [PDB: 6ojt] CMCF-ID Health
Labiuk, Shaunivan L.; Sygusch, Jurgen; Grochulski, Pawel (2019). Structures of soluble rabbit neprilysin complexed with phosphoramidon or thiorphan. Acta Crystallographica Section F:Structural Biology Communications 75(6) , 405-411. 10.1107/s2053230x19006046. Health
Lang, Dean E.; Morris, Jeremy S.; Rowley, Michael; Torres, Miguel A.; Maksimovich, Vook A. et al. (2019). Structure–function studies of tetrahydroprotoberberine N-methyltransferase reveal the molecular basis of stereoselective substrate recognition. Journal of Biological Chemistry 294(40) , jbc.RA119.009214. 10.1074/jbc.ra119.009214. [PDB: 6p3m] CMCF-BM Health
Lei, Ming; Tempel, Wolfram; Chen, Sizhuo; Liu, Ke; Min, Jinrong et al. (2019). Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain. Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1862(9) , 194409. 10.1016/j.bbagrm.2019.194409. CMCF-ID Health
Li, Chen; Zhu, Ning; Emady, Heather N.; Zhang, Lifeng (2019). Synchrotron-based X-ray in-situ imaging techniques for advancing the understanding of pharmaceutical granulation. International Journal of Pharmaceutics 572, 118797. 10.1016/j.ijpharm.2019.118797. BMIT-BM Health
Li, Hao; Schart-Morén, Nadine; Rohani, Seyed Alireza; Ladak, Hanif M.; Rask-Andersen, Helge et al. (2019). Synchrotron Radiation-Based Reconstruction of the Human Spiral Ganglion: Implications for Cochlear Implantation. Ear and Hearing 41(1) , 173–181. 10.1097/aud.0000000000000738. BMIT-ID Health
Li, Jia; Jia, Yunhua; Lin, Aiyang; Hanna, Michelle; Chelico, Linda et al. (2019). Structure of Ddi2, a highly inducible detoxifying metalloenzyme from Saccharomyces cerevisiae. Journal of Biological Chemistry 294(27) , 10674-10685. 10.1074/jbc.ra118.006394. [PDB: 6dk9, 6dka, 6dkc, 6dkd] CMCF-BM, CMCF-ID Health
Li, Tang; Stephen, Preyesh; Zhu, Dao‐Wei; Shi, Rong; Lin, Sheng‐Xiang et al. (2019). Crystal structures of human 17β‐hydroxysteroid dehydrogenase type 1 complexed with estrone andNADP+reveal the mechanism of substrate inhibition. FEBS Journal 286(11) . 10.1111/febs.14784. [PDB: 6mne] CMCF-BM, CMCF-ID Health
Liu, Yanli; Qin, Su; Chen, Tsai-Yu; Lei, Ming; Dhar, Shilpa S. et al. (2019). Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4. Nature Communications 10(1) . 10.1038/s41467-018-07906-3. [PDB: 6mlc] CMCF-ID Health
Li, Zhijie; Tomlinson, Aidan CA; Wong, Alan HM; Zhou, Dongxia; Desforges, Marc et al. (2019). The human coronavirus HCoV-229E S-protein structure and receptor binding. eLife 8. 10.7554/elife.51230. [PDB: 6u7e, 6u7f] CMCF-ID Health
Luan, Xiaojie; Tam, Julian S.; Belev, George; Jagadeeshan, Santosh; Murray, Brendan et al. (2019). Nebulized hypertonic saline triggers nervous system-mediated active liquid secretion in cystic fibrosis swine trachea. Scientific Reports 9(1) , 540. 10.1038/s41598-018-36695-4. BMIT-BM Health
Lu, Zhonghui; Duan, James J.-W.; Xiao, Haiyun; Neels, James; Wu, Dauh-Rurng et al. (2019). Identification of potent, selective and orally bioavailable phenyl ((R)-3-phenylpyrrolidin-3-yl)sulfone analogues as RORγt inverse agonists. Bioorganic and Medicinal Chemistry Letters 29(16) . 10.1016/j.bmcl.2019.06.036. [PDB: 6p9f] CMCF-ID Health
Mabanglo, Mark F.; Leung, Elisa; Vahidi, Siavash; Seraphim, Thiago V.; Eger, Bryan T. et al. (2019). ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores. Communications Biology 2(1) . 10.1038/s42003-019-0656-3. [PDB: 6naq, 6nb1] CMCF-BM Health