Publication Beamlines Strategic Pillar
Jiang, Ying-Ying; Wang, Zhi-Qiang; Chen, Jia-Tang; Li, Jun; Zhu, Ying-Jie et al. (2020). Tracking the interaction of drug molecules with individual mesoporous amorphous calcium phosphate/ATP nanocomposites – an X-ray spectromicroscopy study. Physical Chemistry Chemical Physics 22(23) . 10.1039/d0cp00797h. SGM, SM, SXRMB, VLS-PGM Health
Grant, Benjamin M. M.; Enomoto, Masahiro; Back, Sung-In; Lee, Ki-Young; Gebregiworgis, Teklab et al. (2020). Calmodulin disrupts plasma membrane localization of farnesylated KRAS4b by sequestering its lipid moiety. Science Signaling 13(625) , eaaz0344. 10.1126/scisignal.aaz0344. [PDB: 6os4] CMCF-ID Health
Anderson, Alexander C.; Burnett, Alysha J.N.; Hiscock, Lana; Maly, Kenneth E.; Weadge, Joel T. et al. (2020). The Escherichia coli cellulose synthase subunit G (BcsG) is a Zn2+-dependent phosphoethanolamine transferase. Journal of Biological Chemistry 295(18) , 6225-6235. 10.1074/jbc.ra119.011668. [PDB: 6pcz, 6pd0] CMCF-ID Health
Vance, Tyler D. R.; Guo, Shuaiqi; Assaie-Ardakany, Shayan; Conroy, Brigid; Davies, Peter L. et al. (2019). Structure and functional analysis of a bacterial adhesin sugar-binding domain. PLoS ONE 14(7) , e0220045. 10.1371/journal.pone.0220045. [PDB: 6m8m] CMCF-ID Health
Duan, James J.-W.; Lu, Zhonghui; Jiang, Bin; Stachura, Sylwia; Weigelt, Carolyn A. et al. (2019). Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active RORγt Inverse Agonists. ACS Medicinal Chemistry Letters 10(3) , 367-373. 10.1021/acsmedchemlett.9b00010. [PDB: 6nx1] CMCF-ID Health
Chong, Pek Y.; Shotwell, J. Brad; Miller, John; Price, Daniel J.; Maynard, Andy et al. (2019). Design of N-Benzoxaborole Benzofuran GSK8175—Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor. Journal of Medicinal Chemistry 62(7) , 3254-3267. 10.1021/acs.jmedchem.8b01719. [PDB: 6mvo] CMCF-ID Health
Huhn, Annissa J.; Gardberg, Anna S.; Poy, Florence; Brucelle, Francois; Vivat, Valerie et al. (2020). Early Drug‐Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors. ChemMedChem 15(11) . 10.1002/cmdc.202000007. [PDB: 6v8n] CMCF-ID Health
Mitcheltree, Matthew J.; Li, Derun; Achab, Abdelghani; Beard, Adam; Chakravarthy, Kalyan et al. (2020). Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy. ACS Medicinal Chemistry Letters 11(4) , 582-588. 10.1021/acsmedchemlett.0c00058. [PDB: 6v7c] CMCF-ID Health
Khan, Nimra; Pelletier, Dylan; Veyron, Simon; Croteau, Nathalie; Ichikawa, Muneyoshi et al. (2019). Crystal structure of human PACRG in complex with MEIG1. FEMS Microbiology Ecology . 10.1101/783373. [PDB: 6ndu, 6ucc] CMCF-ID Health
Jones, Darryl R.; Xing, Xiaohui; Tingley, Jeffrey P.; Klassen, Leeann; King, Marissa L. et al. (2020). Analysis of Active Site Architecture and Reaction Product Linkage Chemistry Reveals a Conserved Cleavage Substrate for an Endo-alpha-mannanase within Diverse Yeast Mannans. Journal of Molecular Biology 432(4) , 1083-1097. 10.1016/j.jmb.2019.12.048. [PDB: 6u4z] CMCF-BM Agriculture
Jones, Carys S.; Sychantha, David; Howell, P. Lynne; Clarke, Anthony J. (2020). Structural basis for the O-acetyltransferase function of the extracytoplasmic domain of OatA from Staphylococcus aureus. Journal of Biological Chemistry 295(24) , jbc.RA120.013108. 10.1074/jbc.ra120.013108. [PDB: 6wn9] CMCF-BM Health
Holt, Christian; Hamborg, Louise; Lau, Kelvin; Brohus, Malene; Sørensen, Anders Bundgaard et al. (2020). The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor. Journal of Biological Chemistry 295(22) , jbc.RA120.013430. 10.1074/jbc.ra120.013430. [PDB: 6y4p] CMCF-BM Health
Gobeil, Sophie M. C.; Ebert, Maximillian C. C. J. C.; Park, Jaeok; Gagné, Donald; Doucet, Nicolas et al. (2019). The Structural Dynamics of Engineered β-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function. Scientific Reports 9(1) . 10.1038/s41598-019-42866-8. [PDB: 4r4s] CMCF-ID Health
Bernath, Peter; Dodangodage, Randika; Dulick, Michael; Zhao, Jianbao; Billinghurst, Brant et al. (2020). Absorption cross sections for neopentane broadened by nitrogen in the 3.3 µm region. Journal of Quantitative Spectroscopy and Radiative Transfer 251, 107034. 10.1016/j.jqsrt.2020.107034. FAR-IR Environment
Hömberg, Annkathrin; Obst, Martin; Knorr, Klaus-Holger; Kalbitz, Karsten; Schaller, Jörg et al. (2020). Increased silicon concentration in fen peat leads to a release of iron and phosphate and changes in the composition of dissolved organic matter. Geoderma 374, 114422. 10.1016/j.geoderma.2020.114422. SM Environment