Publication Beamlines Strategic Pillar
Frandoloso, Rafael; Martínez-Martínez, Sonia; Calmettes, Charles; Fegan, Jamie; Costa, Estela et al. (2015). Nonbinding Site-Directed Mutants of Transferrin Binding Protein B Exhibit Enhanced Immunogenicity and Protective Capabilities. Infection and Immunity 83(3) , 1030-1038. 10.1128/iai.02572-14. [PDB: 4o3w, 4o3x, 4o3y, 4o3z, 4o49, 4o4u, 4o4x] CMCF-BM, CMCF-ID Health
Feng, Yuting; Park, Jaeok; Li, Shi-Guang; Boutin, Rebecca; Viereck, Peter et al. (2019). Chirality-Driven Mode of Binding of α-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS). Journal of Medicinal Chemistry 62(21) , 9691-9702. 10.1021/acs.jmedchem.9b01104. [PDB: 6n7y, 6n82, 6n83, 6oag, 6oah] CMCF-BM, CMCF-ID Health
Ereño-Orbea, June; Sicard, Taylor; Cui, Hong; Mazhab-Jafari, Mohammad T.; Benlekbir, Samir et al. (2017). Molecular basis of human CD22 function and therapeutic targeting. Nature Communications 8(1) . 10.1038/s41467-017-00836-6. [PDB: 5vkj, 5vkk, 5vkm, 5vl3] CMCF-BM, CMCF-ID Health
Doyle, Liam; Ovchinnikova, Olga G.; Myler, Katharine; Mallette, Evan; Huang, Bo-Shun et al. (2019). Biosynthesis of a conserved glycolipid anchor for Gram-negative bacterial capsules. Nature Chemical Biology 15(6) . 10.1038/s41589-019-0276-8. [PDB: 6mgb, 6mgc, 6mgd] CMCF-BM, CMCF-ID Health
Cuskin, Fiona; Lowe, Elisabeth C.; Temple, Max J.; Zhu, Yanping; Cameron, Elizabeth A. et al. (2015). Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism. Nature 517(7533) , 165-169. 10.1038/nature13995. [PDB: 4c1r, 4c1s] CMCF-BM, CMCF-ID Health
Crowe, Adam M.; Workman, Sean D.; Watanabe, Nobuhiko; Worrall, Liam J.; Strynadka, Natalie C. J. et al. (2018). IpdAB, a virulence factor in Mycobacterium tuberculosis , is a cholesterol ring-cleaving hydrolase. Proceedings of the National Academy of Sciences of the United States of America 115(15) , E3378-E3387. 10.1073/pnas.1717015115. [PDB: 6co6, 6co9, 6coj, 6con] CMCF-BM Health
Conly, Cuylar J. T.; Skovpen, Yulia V.; Li, Shuo; Palmer, David R. J.; Sanders, David A. R. et al. (2014). Tyrosine 110 Plays a Critical Role in Regulating the Allosteric Inhibition of Campylobacter jejuni Dihydrodipicolinate Synthase by Lysine. Biochemistry 53(47) , 7396-7406. 10.1021/bi5012157. [PDB: 4ly8, 4m19, 4mlj, 4mlr, 4r53] CMCF-BM, CMCF-ID Health
Chan, Anson C.K.; Blair, Kris M.; Liu, Yanjie; Frirdich, Emilisa; Gaynor, Erin C. et al. (2015). Helical Shape of Helicobacter pylori Requires an Atypical Glutamine as a Zinc Ligand in the Carboxypeptidase Csd4. Journal of Biological Chemistry 290(6) , jbc.M114.624734. 10.1074/jbc.m114.624734. [PDB: 4wck, 4wcl, 4wcm, 4wcn] CMCF-BM, CMCF-ID Health
Caveney, Nathanael A.; Pavlin, Anja; Caballero, Guillermo; Bahun, Miha; Hodnik, Vesna et al. (2019). Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host LexA Repressor. Structure 27(7) . 10.1016/j.str.2019.03.019. [PDB: 6n7o] CMCF-BM, CMCF-ID Health
Caveney, Nathanael A.; Caballero, Guillermo; Voedts, Henri; Niciforovic, Ana; Worrall, Liam J. et al. (2019). Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli. Nature Communications 10(1) . 10.1038/s41467-019-09507-0. [PDB: 6ntz] CMCF-BM, CMCF-ID Health
Blank, Matthew L.; Parker, Michelle L.; Ramaswamy, Raghavendran; Powell, Cameron J.; English, Elizabeth D. et al. (2018). A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions. Molecular Microbiology 108(5) , 519-535. 10.1111/mmi.13947. [PDB: 6bxr, 6bxs] CMCF-BM, CMCF-ID Health
Bie, Haiying; Yin, Jiang; He, Xu; Kermode, Allison R; Goddard-Borger, Ethan D et al. (2013). Insights into mucopolysaccharidosis I from the structure and action of α-L-iduronidase. Nature Chemical Biology 9(11) , 739-745. 10.1038/nchembio.1357. [PDB: 4mj2, 4mj4] CMCF-BM, CMCF-ID Health
Bergeron, Julien R.C.; Worrall, Liam J.; De, Soumya; Sgourakis, Nikolaos G.; Cheung, Adrienne H. et al. (2015). The Modular Structure of the Inner-Membrane Ring Component PrgK Facilitates Assembly of the Type III Secretion System Basal Body. Structure 23(1) , 161-172. 10.1016/j.str.2014.10.021. [PDB: 4oyc, 4w4m] CMCF-BM Health
Bergeron, Julien R.C.; Fernández, Lucia; Wasney, Gregory A.; Vuckovic, Marija; Reffuveille, Fany et al. (2016). The Structure of a Type 3 Secretion System (T3SS) Ruler Protein Suggests a Molecular Mechanism for Needle Length Sensing. Journal of Biological Chemistry 291(4) , 1676-1691. 10.1074/jbc.m115.684423. [PDB: 5cuk, 5cul] CMCF-BM, CMCF-ID Health
Baral, Pravas Kumar; Swayampakula, Mridula; Aguzzi, Adriano; James, Michael N.G. (2015). X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins. Journal of Structural Biology 192(1) , 37-47. 10.1016/j.jsb.2015.08.014. [PDB: 4yx2] CMCF-BM Health