Publication Beamlines Strategic Pillar
Hughes, Scott J.; Antoshchenko, Tetyana; Chen, Yun; Lu, Hua; Pizarro, Juan C. et al. (2016). Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs. PLoS ONE 11(5) , e0154862. 10.1371/journal.pone.0154862. [PDB: 5evz, 5ex5, 5exw, 5f0x, 5f2r] CMCF-ID Health
Hughes, Scott J.; Barnard, Leanne; Mottaghi, Katayoun; Tempel, Wolfram; Antoshchenko, Tetyana et al. (2016). Discovery of Potent Pantothenamide Inhibitors of Staphylococcus aureus Pantothenate Kinase through a Minimal SAR Study: Inhibition Is Due to Trapping of the Product. ACS Infectious Diseases 2(9) , 627-641. 10.1021/acsinfecdis.6b00090. [PDB: 5jic] CMCF-ID Health
Hughes, S.J.; Antoshchenko, T.; Mottaghi, K.; Barnard, L.; Strauss, E. et al. (2016). Staphylococcus aureus Type II pantothenate kinase in complex with a pantothenate analog. Protein Data Bank: 5jic. CMCF-ID Health
Hughes, S.J.; Antoshchenko, T.; Song, J.H.; Pizarro, J.; Park, H.W. et al. (2016). Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with 7-deaza-ATP. Protein Data Bank: 5exw. CMCF-ID Health
Hughes, S.J.; Antoshchenko, T.; Song, J.H.; Pizarro, J.; Park, H.W. et al. (2016). Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with AMP-PCP. Protein Data Bank: 5f2r. CMCF-ID Health
Hughes, S.J.; Antoshchenko, T.; Song, J.H.; Pizarro, J.; Park, H.W. et al. (2016). Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with 7-deaza-ADP and inorganic phosphate. Protein Data Bank: 5ex5. CMCF-ID Health
Hughes, S.J.; Antoshchenko, T.; Song, J.H.; Pizarro, J.; Park, H.W. et al. (2016). Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with ADP and inorganic phosphate. Protein Data Bank: 5evz. CMCF-ID Health
Hughes, S.J.; Antoshchenko, T.; Song, J.H.; Pizarro, J.; Park, H.W. et al. (2016). Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with 2'-deoxy-ADP and inorganic phosphate. Protein Data Bank: 5f0x. CMCF-ID Health
Huguenin-Dezot, Nicolas; Alonzo, Diego A.; Heberlig, Graham W.; Mahesh, Mohan; Nguyen, Duy P. et al. (2018). Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid. Nature 565(7737) , 112-117. 10.1038/s41586-018-0781-z. [PDB: 6ecb, 6ecc, 6ece, 6ecf] CMCF-ID Health
Huh, Ian; Gene, Robert; Kumaran, Jyothi; MacKenzie, C. Roger; Brooks, Cory L. et al. (2014). In situproteolysis, crystallization and preliminary X-ray diffraction analysis of a VHH that binds listeria internalin B. Acta Crystallographica Section F:Structural Biology Communications 70(11) , 1532-1535. 10.1107/s2053230x1402010x. CMCF-ID Health
Hu, Jinhong; Komakula, Aruna; Fraser, Marie E. (2017). Binding of hydroxycitrate to human ATP-citrate lyase. Acta Crystallographica Section D: Structural Biology 73(8) , 660-671. 10.1107/s2059798317009871. [PDB: 5tde, 5tdf, 5tdm, 5tdz, 5te1, 5teq, 5tes, 5tet] CMCF-BM, CMCF-ID Health
Hynes, John; Wu, Hong; Kempson, James; Duan, James J.-W.; Lu, Zhonghui et al. (2017). Discovery of potent and efficacious pyrrolopyridazines as dual JAK1/3 inhibitors. Bioorganic and Medicinal Chemistry Letters 27(14) , 3101-3106. 10.1016/j.bmcl.2017.05.043. [PDB: 5vo6] CMCF-ID Health
Iancu, Cristina V.; Zamoon, Jamillah; Woo, Sang Bum; Aleshin, Alexander; Choe, Jun-yong et al. (2013). Crystal structure of a glucose/H + symporter and its mechanism of action. Proceedings of the National Academy of Sciences of the United States of America 110(44) , 17862-17867. 10.1073/pnas.1311485110. CMCF-ID Health
Imkeller, Katharina; Scally, Stephen W.; Bosch, Alexandre; Martí, Gemma Pidelaserra; Costa, Giulia et al. (2018). Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope. Science 360(6395) , 1358-1362. 10.1126/science.aar5304. [PDB: 6d01, 6d11] CMCF-ID Health
Ishiyama, N.; Ikura, M. (2018). Crystal structure of the alpha-E-catenin actin-binding domain. Protein Data Bank: 6dv1. CMCF-ID Health