| Hettle, John Andrew (2018). Carrageenan desulfation and depolymerization by the marine isolate Pseudoalteromonas sp. PS47. Supervisor: Boraston, Alisdair B.. British Columbia, Canada: University of Victoria. https://dspace.library.uvic.ca/items/d9ce3972-f500-4871-9e0a-f252ce0277f9. |
CMCF-ID |
Doctoral Thesis |
Health |
| Hettle, Andrew G.; Vickers, Chelsea; Robb, Craig S.; Liu, Feng; Withers, Stephen G. et al. (2018). The Molecular Basis of Polysaccharide Sulfatase Activity and a Nomenclature for Catalytic Subsites in this Class of Enzyme. Structure 26(5) , 747-758.e4. 10.1016/j.str.2018.03.012. [PDB: 6b0k] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Heron, P.W.; Sygusch, J. (2017). Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor naphthalene 2,6-bisphosphate. Protein Data Bank: 5tlz. |
CMCF-ID |
PDB Deposition |
Health |
| Heron, P.W.; Sygusch, J. (2017). Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 1-phosphate-benzene 4-bisphosphonate. Protein Data Bank: 5tlw. |
CMCF-ID |
PDB Deposition |
Health |
| Heron, P.W.; Sygusch, J. (2017). Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 2-naphthol 6-bisphosphonate. Protein Data Bank: 5tlh. |
CMCF-ID |
PDB Deposition |
Health |
| Heron, Paul W.; Abellán-Flos, Marta; Salmon, Laurent; Sygusch, Jurgen (2018). Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase. Journal of Medicinal Chemistry 61(23) , 10558-10572. 10.1021/acs.jmedchem.8b01000. [PDB: 5tle, 5tlh, 5tlw, 5tlz] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Herold, J. Martin; Wigle, Tim J.; Norris, Jacqueline L.; Lam, Robert; Korboukh, Victoria K. et al. (2011). Small-Molecule Ligands of Methyl-Lysine Binding Proteins. Journal of Medicinal Chemistry 54(7) , 2504-2511. 10.1021/jm200045v. [PDB: 3p8h] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Hehemann, J.H.; Smyth, L.; Yadav, A.; Vocadlo, D.J.; Boraston, A.B. et al. (2012). Crystal structure of BpGH117_E303Q in complex with neoagarobiose. Protein Data Bank: 4ak7. |
CMCF-ID |
PDB Deposition |
Health |
| Hehemann, J.H.; Kelly, A.G.; Pudlo, N.A.; Martens, E.C.; Boraston, A.B. et al. (2012). BpGH86A: A beta-porphyranase of glycoside hydrolase family 86 from the human gut bacterium Bacteroides plebeius. Protein Data Bank: 4aw7. |
CMCF-ID |
PDB Deposition |
Health |
| Hehemann, Jan-Hendrik; Smyth, Leo; Yadav, Anuj; Vocadlo, David J.; Boraston, Alisdair B. et al. (2012). Analysis of Keystone Enzyme in Agar Hydrolysis Provides Insight into the Degradation (of a Polysaccharide from) Red Seaweeds. Journal of Biological Chemistry 287(17) , 13985-13995. 10.1074/jbc.m112.345645. [PDB: 4ak7] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Hehemann, Jan-Hendrik; Kelly, Amelia G.; Pudlo, Nicholas A.; Martens, Eric C.; Boraston, Alisdair B. et al. (2012). Bacteria of the human gut microbiome catabolize red seaweed glycans with carbohydrate-active enzyme updates from extrinsic microbes. Proceedings of the National Academy of Sciences of the United States of America 109(48) , 19786-19791. 10.1073/pnas.1211002109. [PDB: 4aw7] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Hedges, Jason B.; Kuatsjah, Eugene; Du, Yi-Ling; Eltis, Lindsay D.; Ryan, Katherine S. et al. (2018). Snapshots of the Catalytic Cycle of an O2, Pyridoxal Phosphate-Dependent Hydroxylase. ACS Chemical Biology 13(4) , 965-974. 10.1021/acschembio.8b00039. [PDB: 6c3a, 6c3b, 6c3c, 6c3d] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Heald, Robert; Bowman, Krista K.; Bryan, Marian C.; Burdick, Daniel; Chan, Bryan et al. (2015). Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study. Journal of Medicinal Chemistry 58(22) , 8877-8895. 10.1021/acs.jmedchem.5b01412. [PDB: 5cal, 5cao, 5cap] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Harikrishnan, Lalgudi S.; Kamau, Muthoni G.; Wan, Honghe; Inghrim, Jennifer A.; Zimmermann, Kurt et al. (2011). Pyrrolo[1,2-f]triazines as JAK2 inhibitors: Achieving potency and selectivity for JAK2 over JAK3. Bioorganic and Medicinal Chemistry Letters 21(5) , 1425-1428. 10.1016/j.bmcl.2011.01.022. [PDB: 3q32] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Han Li; Dorothea Kominos; Jie Zhang; Alla Pritsker; Matthew Davison et al. (2018). Methods for treating pain using antibodies to Kallidin and des-Arg10-Kallidin. Patent Number: US9879079B2. |
CMCF-ID |
Patent |
Health |