Publication Beamlines Strategic Pillar
Ghosh, Kaushik; Mazumder Tagore, Debarati; Anumula, Rushith; Lakshmaiah, Basanth; Kumar, P.P.B.S. et al. (2013). Crystal structure of rat intestinal alkaline phosphatase – Role of crown domain in mammalian alkaline phosphatases. Journal of Structural Biology 184(2) , 182-192. 10.1016/j.jsb.2013.09.017. [PDB: 4kjg] CMCF-ID Health
Gobeil, Sophie M.C.; Clouthier, Christopher M.; Park, Jaeok; Gagné, Donald; Berghuis, Albert M. et al. (2014). Maintenance of Native-like Protein Dynamics May Not Be Required for Engineering Functional Proteins. Chemistry & Biology 21(10) , 1330-1340. 10.1016/j.chembiol.2014.07.016. [PDB: 4id4] CMCF-ID Health
Gomery, Kathryn; Müller-Loennies, Sven; Brooks, Cory L.; Brade, Lore; Kosma, Paul et al. (2012). Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS. Proceedings of the National Academy of Sciences of the United States of America 109(51) , 20877-20882. 10.1073/pnas.1209253109. [PDB: 3v0w] CMCF-ID Health
Gong, Hua; Weinstein, David S.; Lu, Zhonghui; Duan, James J.-W.; Stachura, Sylwia et al. (2018). Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity. Bioorganic and Medicinal Chemistry Letters 28(2) , 85-93. 10.1016/j.bmcl.2017.12.006. [PDB: 6bns] CMCF-ID Health
González, Javier M.; Marti-Arbona, Ricardo; Chen, Julian C.-H.; Broom-Peltz, Brian; Unkefer, Clifford J. et al. (2018). Conformational changes on substrate binding revealed by structures of Methylobacterium extorquens malate dehydrogenase. Acta Crystallographica Section F:Structural Biology Communications 74(10) , 610-616. 10.1107/s2053230x18011809. [PDB: 5ujk] CMCF-ID Health
Gonzalez-Lopez de Turiso, Felix; Sun, Daqing; Rew, Yosup; Bartberger, Michael D.; Beck, Hilary P. et al. (2013). Rational Design and Binding Mode Duality of MDM2–p53 Inhibitors. Journal of Medicinal Chemistry 56(10) , 4053-4070. 10.1021/jm400293z. [PDB: 4jwr] CMCF-ID Health
Gorelik, Alexei; Gebai, Ahmad; Illes, Katalin; Piomelli, Daniele; Nagar, Bhushan et al. (2018). Molecular mechanism of activation of the immunoregulatory amidase NAAA. Proceedings of the National Academy of Sciences of the United States of America 115(43) , E10032-E10040. 10.1073/pnas.1811759115. [PDB: 6dxw, 6dxx, 6dxy, 6dxz, 6dy0, 6dy1, 6dy2, 6dy3] CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Heinz, Leonhard X.; Illes, Katalin; Superti-Furga, Giulio; Nagar, Bhushan et al. (2016). Crystal Structure of the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3B Provides Insights into Determinants of Substrate Specificity. Journal of Biological Chemistry 291(46) , 24054-24064. 10.1074/jbc.m116.755801. CMCF-ID Health
Gorelik, Alexei; Illes, Katalin; Heinz, Leonhard X.; Superti-Furga, Giulio; Nagar, Bhushan et al. (2016). Crystal structure of mammalian acid sphingomyelinase. Nature Communications 7(1) . 10.1038/ncomms12196. [PDB: 5fi9, 5fib, 5fic, 5hqn] CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Illes, Katalin; Nagar, Bhushan (2018). Crystal structure of the mammalian lipopolysaccharide detoxifier. Proceedings of the National Academy of Sciences of the United States of America 115(5) , E896-E905. 10.1073/pnas.1719834115. [PDB: 5w78, 5w7a, 5w7b, 5w7c, 5w7d, 5w7e, 5w7f] CMCF-ID Health
Gorelik, Alexei; Illes, Katalin; Superti-Furga, Giulio; Nagar, Bhushan (2016). Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A. Journal of Biological Chemistry 291(12) , 6376-6385. 10.1074/jbc.m115.711085. [PDB: 5fc1, 5fc6, 5fc7, 5fca, 5fcb] CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Liu, Fangyu; Illes, Katalin; Nagar, Bhushan (2017). Crystal structure of the human alkaline sphingomyelinase provides insights into substrate recognition. Journal of Biological Chemistry 292(17) , 7087-7094. 10.1074/jbc.m116.769273. [PDB: 5tcd, 5udy] CMCF-ID Health
Gorelik, Alexei; Randriamihaja, Antsa; Illes, Katalin; Nagar, Bhushan (2018). Structural basis for nucleotide recognition by the ectoenzyme CD 203c. FEBS Journal 285(13) . 10.1111/febs.14489. [PDB: 6c01, 6c02] CMCF-ID Health
Gorelik, Alexei; Randriamihaja, Antsa; Illes, Katalin; Nagar, Bhushan (2017). A key tyrosine substitution restricts nucleotide hydrolysis by the ectoenzyme NPP 5. FEBS Journal 284(21) , 3718-3726. 10.1111/febs.14266. [PDB: 5vem, 5ven] CMCF-ID Health
Gould, Alister D.; Shilton, Brian H. (2010). Studies of the Maltose Transport System Reveal a Mechanism for Coupling ATP Hydrolysis to Substrate Translocation without Direct Recognition of Substrate. Journal of Biological Chemistry 285(15) , 11290-11296. 10.1074/jbc.m109.089078. [PDB: 3hpi, 3kjt] CMCF-ID Health