Publication Beamlines Strategic Pillar
Wiseman, Ben; Carpena, Xavi; Feliz, Miguel; Donald, Lynda J.; Pons, Miquel et al. (2010). Isonicotinic Acid Hydrazide Conversion to Isonicotinyl-NAD by Catalase-peroxidases. Journal of Biological Chemistry 285(34) , 26662-26673. 10.1074/jbc.m110.139428. [PDB: 5sxq, 5sxr, 5sxs, 5sxt, 5sxw, 5sxx] CMCF-ID Health
Wilsbacher, Julie L.; Cheng, Min; Cheng, Dong; Trammell, Samuel A.J.; Shi, Yan et al. (2017). Discovery and Characterization of Novel Nonsubstrate and Substrate NAMPT Inhibitors. Molecular Cancer Therapeutics 16(7) , 1236-1245. 10.1158/1535-7163.mct-16-0819. [PDB: 5u2m] CMCF-ID Health
Williamson, Michael R.; Dietrich, Kristen; Hackett, Mark J.; Caine, Sally; Nadeau, Colby A. et al. (2017). Rehabilitation Augments Hematoma Clearance and Attenuates Oxidative Injury and Ion Dyshomeostasis After Brain Hemorrhage. Stroke 48(1) , 195-203. 10.1161/strokeaha.116.015404. MID-IR Health
White, E. Railey; Sun, Luxin; Ma, Zhong; Beckta, Jason M.; Danzig, Brittany A. et al. (2015). Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain. ACS Chemical Biology 10(5) , 1198-1208. 10.1021/cb500757u. [PDB: 4ofb] CMCF-BM, CMCF-ID Health
White, E. Railey; Sun, Luxin; Ma, Zhong; Beckta, Jason M.; Danzig, Brittany A. et al. (2015). Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain. ACS Chemical Biology 10(5) , 1198-1208. 10.1021/cb500757u. [PDB: 4ofb] CMCF-BM, CMCF-ID Health
Wheatley, Robert W.; Zheng, Ruixiang Blake; Richards, Michele R.; Lowary, Todd L.; Ng, Kenneth K.S. et al. (2012). Tetrameric Structure of the GlfT2 Galactofuranosyltransferase Reveals a Scaffold for the Assembly of Mycobacterial Arabinogalactan. Journal of Biological Chemistry 287(33) , 28132-28143. 10.1074/jbc.m112.347484. CMCF-ID Health
Wheatley, Robert W.; Ng, Kenneth K.S.; Kapoor, Manju (2016). Fungal cobalamin-independent methionine synthase: Insights from the model organism, Neurospora crassa. Archives of Biochemistry and Biophysics 590, 125-137. 10.1016/j.abb.2015.11.037. [PDB: 4zty] CMCF-ID Health
Wheatley, Robert W.; Lo, Summie; Jancewicz, Larisa J.; Dugdale, Megan L.; Huber, Reuben E. et al. (2013). Structural Explanation for Allolactose (lac Operon Inducer) Synthesis by lacZ β-Galactosidase and the Evolutionary Relationship between Allolactose Synthesis and the lac Repressor. Journal of Biological Chemistry 288(18) , 12993-13005. 10.1074/jbc.m113.455436. [PDB: 4duw, 4dux] CMCF-BM Health
Wernimont, Amy K.; Amani, Merhnaz; Qiu, Wei; Pizarro, Juan C.; Artz, Jennifer D. et al. (2010). Structures of parasitic CDPK domains point to a common mechanism of activation. Proteins: Structure. Function and Bioinformatics 79(3) , 803-820. 10.1002/prot.22919. [PDB: 3k21] CMCF-ID Health
Watterson, Scott H.; De Lucca, George V.; Shi, Qing; Langevine, Charles M.; Liu, Qingjie et al. (2016). Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton’s Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers. Journal of Medicinal Chemistry 59(19) , 9173-9200. 10.1021/acs.jmedchem.6b01088. [PDB: 5t18] CMCF-ID Health
Watanabe, Nobuhiko; Clay, Matthew D.; van Belkum, Marco J.; Fan, Chenguang; Vederas, John C. et al. (2011). The Structure of ll-Diaminopimelate Aminotransferase from Chlamydia trachomatis: Implications for Its Broad Substrate Specificity. Journal of Molecular Biology 411(3) , 649-660. 10.1016/j.jmb.2011.06.023. [PDB: 3asb] CMCF-ID Health
Wan, Honghe; Schroeder, Gretchen M.; Hart, Amy C.; Inghrim, Jennifer; Grebinski, James et al. (2015). Discovery of a Highly Selective JAK2 Inhibitor, BMS-911543, for the Treatment of Myeloproliferative Neoplasms. ACS Medicinal Chemistry Letters 6(8) , 850-855. 10.1021/acsmedchemlett.5b00226. [PDB: 5cf8] CMCF-ID Health
Wahba, Haytham M.; Stevenson, Michael J.; Mansour, Ahmed; Sygusch, Jurgen; Wilcox, Dean E. et al. (2017). Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon–Metal Bond Cleavage. Journal of the American Chemical Society 139(2) , 910-921. 10.1021/jacs.6b11327. [PDB: 5u79, 5u7b, 5u7c, 5u82, 5u83] CMCF-ID Health
Wagner, Florence F.; Benajiba, Lina; Campbell, Arthur J.; Weïwer, Michel; Sacher, Joshua R. et al. (2018). Exploiting an Asp-Glu “switch” in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Science Translational Medicine 10(431) , eaam8460. 10.1126/scitranslmed.aam8460. [PDB: 5kpl, 5kpm] CMCF-ID Health
Voth, Kevin A.; Chung, Ivy Yeuk Wah; Straaten, Karin; Li, Lei; Boniecki, Michal T. et al. (2018). The structure of Legionella effector protein LpnE provides insights into its interaction with Oculocerebrorenal syndrome of Lowe ( OCRL ) protein. FEBS Journal 286(4) , 710-725. 10.1111/febs.14710. [PDB: 6deh] CMCF-ID Health