Hehemann, Jan-Hendrik; Kelly, Amelia G.; Pudlo, Nicholas A.; Martens, Eric C.; Boraston, Alisdair B. et al. (2012). Bacteria of the human gut microbiome catabolize red seaweed glycans with carbohydrate-active enzyme updates from extrinsic microbes. Proceedings of the National Academy of Sciences of the United States of America 109(48) , 19786-19791. 10.1073/pnas.1211002109. [PDB: 4aw7] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Hehemann, Jan-Hendrik; Smyth, Leo; Yadav, Anuj; Vocadlo, David J.; Boraston, Alisdair B. et al. (2012). Analysis of Keystone Enzyme in Agar Hydrolysis Provides Insight into the Degradation (of a Polysaccharide from) Red Seaweeds. Journal of Biological Chemistry 287(17) , 13985-13995. 10.1074/jbc.m112.345645. [PDB: 4ak7] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Hehemann, J.H.; Kelly, A.G.; Pudlo, N.A.; Martens, E.C.; Boraston, A.B. et al. (2012). BpGH86A: A beta-porphyranase of glycoside hydrolase family 86 from the human gut bacterium Bacteroides plebeius. Protein Data Bank: 4aw7. |
CMCF-ID |
PDB Deposition |
Health |
Hehemann, J.H.; Smyth, L.; Yadav, A.; Vocadlo, D.J.; Boraston, A.B. et al. (2012). Crystal structure of BpGH117_E303Q in complex with neoagarobiose. Protein Data Bank: 4ak7. |
CMCF-ID |
PDB Deposition |
Health |
Herold, J. Martin; Wigle, Tim J.; Norris, Jacqueline L.; Lam, Robert; Korboukh, Victoria K. et al. (2011). Small-Molecule Ligands of Methyl-Lysine Binding Proteins. Journal of Medicinal Chemistry 54(7) , 2504-2511. 10.1021/jm200045v. [PDB: 3p8h] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Heron, Paul W.; Abellán-Flos, Marta; Salmon, Laurent; Sygusch, Jurgen (2018). Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase. Journal of Medicinal Chemistry 61(23) , 10558-10572. 10.1021/acs.jmedchem.8b01000. [PDB: 5tle, 5tlh, 5tlw, 5tlz] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Heron, Paul W.; Abellán-Flos, Marta; Salmon, Laurent; Sygusch, Jurgen (2018). Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase. Journal of Medicinal Chemistry 61(23) , 10558-10572. 10.1021/acs.jmedchem.8b01000. [PDB: 5tle, 5tlh, 5tlw, 5tlz] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Heron, P.W.; Sygusch, J. (2017). Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor naphthalene 2,6-bisphosphate. Protein Data Bank: 5tlz. |
CMCF-ID |
PDB Deposition |
Health |
Heron, P.W.; Sygusch, J. (2017). Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 1-phosphate-benzene 4-bisphosphonate. Protein Data Bank: 5tlw. |
CMCF-ID |
PDB Deposition |
Health |
Heron, P.W.; Sygusch, J. (2017). Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 2-naphthol 6-bisphosphonate. Protein Data Bank: 5tlh. |
CMCF-ID |
PDB Deposition |
Health |
Heron, P.W.; Sygusch, J. (2017). Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with the inhibitor 2-phosphate-naphthalene 6-bisphosphonate. Protein Data Bank: 5tle. |
CMCF-BM |
PDB Deposition |
Health |
Hettle, Andrew G.; Vickers, Chelsea; Robb, Craig S.; Liu, Feng; Withers, Stephen G. et al. (2018). The Molecular Basis of Polysaccharide Sulfatase Activity and a Nomenclature for Catalytic Subsites in this Class of Enzyme. Structure 26(5) , 747-758.e4. 10.1016/j.str.2018.03.012. [PDB: 6b0k] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Hewitt, Stephen Nakazawa; Dranow, David M.; Horst, Benjamin G.; Abendroth, Jan A.; Forte, Barbara et al. (2016). Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase. ACS Infectious Diseases 3(1) , 34-44. 10.1021/acsinfecdis.6b00078. [PDB: 4wi1, 5ifu] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Hewitt, Stephen N.; Choi, Ryan; Kelley, Angela; Crowther, Gregory J.; Napuli, Alberto J. et al. (2011). Expression of proteins inEscherichia colias fusions with maltose-binding protein to rescue non-expressed targets in a high-throughput protein-expression and purification pipeline. Acta Crystallographica Section F Structural Biology and Crystallization Communications 67(9) , 1006-1009. 10.1107/s1744309111022159. [PDB: 3u40] |
CMCF-ID |
Peer-Reviewed Article |
Health |
He, Xiao; Szewczyk, Paul; Karyakin, Andrey; Evin, Mariah; Hong, Wen-Xu et al. (2010). Structure of a cation-bound multidrug and toxic compound extrusion transporter. Nature 467(7318) , 991-994. 10.1038/nature09408. |
CMCF-ID |
Peer-Reviewed Article |
Health |