Publication Beamlines Strategic Pillar
Bains, Jasleen; Leon, Rafael; Temke, Kevin G.; Boulanger, Martin J. (2011). Elucidating the reaction mechanism of the benzoate oxidation pathway encoded aldehyde dehydrogenase fromBurkholderia xenovoransLB400. Protein Science 20(6) , 1048-1059. 10.1002/pro.639. [PDB: 2y51, 2y52, 2y53, 2y5d] CMCF-ID Health
Bagal, Sharan K.; Omoto, Kiyoyuki; Blakemore, David C.; Bungay, Peter J.; Bilsland, James G. et al. (2018). Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors. Journal of Medicinal Chemistry 62(1) , 247-265. 10.1021/acs.jmedchem.8b00280. [PDB: 6d20] CMCF-ID Health
Bagal, Sharan K.; Andrews, Mark; Bechle, Bruce M.; Bian, Jianwei; Bilsland, James et al. (2018). Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain. Journal of Medicinal Chemistry 61(15) , 6779-6800. 10.1021/acs.jmedchem.8b00633. [PDB: 6dkb] CMCF-ID Health
Bacik, John-Paul; Whitworth, Garrett E.; Stubbs, Keith A.; Yadav, Anuj K.; Martin, Dylan R. et al. (2011). Molecular Basis of 1,6-Anhydro Bond Cleavage and Phosphoryl Transfer by Pseudomonas aeruginosa 1,6-Anhydro-N-acetylmuramic Acid Kinase. Journal of Biological Chemistry 286(14) , 12283-12291. 10.1074/jbc.m110.198317. [PDB: 3qbw, 3qbx] CMCF-ID Health
Bacik, John-Paul; Whitworth, Garrett E.; Stubbs, Keith A.; Vocadlo, David J.; Mark, Brian L. et al. (2012). Active Site Plasticity within the Glycoside Hydrolase NagZ Underlies a Dynamic Mechanism of Substrate Distortion. Chemistry & Biology 19(11) , 1471-1482. 10.1016/j.chembiol.2012.09.016. [PDB: 4gvf, 4gvg, 4gvh, 4gyj, 4gyk] CMCF-ID Health
Bacik, John-Paul; Tavassoli, Marjan; Patel, Trushar R.; McKenna, Sean A.; Vocadlo, David J. et al. (2014). Conformational Itinerary of Pseudomonas aeruginosa 1,6-Anhydro-N-acetylmuramic Acid Kinase during Its Catalytic Cycle. Journal of Biological Chemistry 289(7) , 4504-4514. 10.1074/jbc.m113.521633. [PDB: 4mo4, 4mo5] CMCF-ID Health
Azoitei, Mihai L.; Ban, Yih-En Andrew; Julien, Jean-Philippe; Bryson, Steve; Schroeter, Alexandria et al. (2012). Computational Design of High-Affinity Epitope Scaffolds by Backbone Grafting of a Linear Epitope. Journal of Molecular Biology 415(1) , 175-192. 10.1016/j.jmb.2011.10.003. [PDB: 3rhu] CMCF-ID Health
Aydin, Halil; Sultana, Azmiri; Li, Sheng; Thavalingam, Annoj; Lee, Jeffrey E. et al. (2016). Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex. Nature 534(7608) , 562-565. 10.1038/nature18595. [PDB: 5f4e, 5f4t, 5f4v] CMCF-ID Health
Aydin, Halil; Smrke, Brianna M.; Lee, Jeffrey E. (2013). Structural characterization of a fusion glycoprotein from a retrovirus that undergoes a hybrid 2‐step entry mechanism. FASEB Journal 27(12) , 5059-5071. 10.1096/fj.13-232371. [PDB: 5h9c] CMCF-ID Health
Axerio-Cilies, Peter; See, Raymond H; Zoraghi, Roya; Worral, Liam; Lian, Tian et al. (2011). Cheminformatics-Driven Discovery of Selective, Nanomolar Inhibitors for Staphylococcal Pyruvate Kinase. ACS Chemical Biology 7(2) , 350-359. 10.1021/cb2003576. [PDB: 3t0t] CMCF-ID Health
Awad, Mark M.; Katayama, Ryohei; McTigue, Michele; Liu, Wei; Deng, Ya-Li et al. (2013). Acquired Resistance to Crizotinib from a Mutation in CD74–ROS1. New England Journal of Medicine 368(25) , 2395-2401. 10.1056/nejmoa1215530. [PDB: 3zbf] CMCF-ID Health
Arnal, Gregory; Stogios, Peter J.; Asohan, Jathavan; Skarina, Tatiana; Savchenko, Alexei et al. (2018). Structural enzymology reveals the molecular basis of substrate regiospecificity and processivity of an exemplar bacterial glycoside hydrolase family 74 endo-xyloglucanase. Biochemical Journal 475(24) , 3963-3978. 10.1042/bcj20180763. [PDB: 6mgl] CMCF-ID Health
Amunugama, Ravindra; He, Yujiong; Willcox, Smaranda; Forties, Robert A.; Shim, Kang-Sup et al. (2012). RAD51 Protein ATP Cap Regulates Nucleoprotein Filament Stability. Journal of Biological Chemistry 287(12) , 8724-8736. 10.1074/jbc.m111.239426. [PDB: 3ntu] CMCF-ID Health
Amador, Fernando J.; Kimlicka, Lynn; Stathopulos, Peter B.; Gasmi-Seabrook, Geneviève M.C.; MacLennan, David H. et al. (2013). Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic α-Helix That Transitions to a β-Strand in a Mutant Linked with a Heritable Cardiomyopathy. Journal of Molecular Biology 425(21) , 4034-4046. 10.1016/j.jmb.2013.08.015. [PDB: 4kei, 4kej, 4kek] CMCF-ID Health
Alexander, J. Andrew N.; Chatterjee, Som S.; Hamilton, Stephanie M.; Eltis, Lindsay D.; Chambers, Henry F. et al. (2018). Structural and kinetic analyses of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in Staphylococcus aureus. Journal of Biological Chemistry 293(51) , 19854-19865. 10.1074/jbc.ra118.004952. [PDB: 5tw4, 5tw8, 5tx9, 5txi, 5ty2, 5ty7, 6c39, 6c3k] CMCF-BM, CMCF-ID Health