Publication Beamlines Strategic Pillar
Vadlamani, G.; Mark, B.L. (2017). Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to (3S,4R,5R,6S)-3-butyryl-4,5,6-trihydroxyazepane. Protein Data Bank: 5utr. CMCF-BM Health
Vadlamani, Grishma; Stubbs, Keith A.; Désiré, Jérôme; Blériot, Yves; Vocadlo, David J. et al. (2017). Conformational flexibility of the glycosidase NagZ allows it to bind structurally diverse inhibitors to suppress β-lactam antibiotic resistance. Protein Science 26(6) , 1161-1170. 10.1002/pro.3166. [PDB: 5utr] CMCF-BM Health
Alaverdashvili, Mariam; Hackett, Mark J.; Caine, Sally; Paterson, Phyllis G. (2017). Parallel changes in cortical neuron biochemistry and motor function in protein-energy malnourished adult rats. NeuroImage 149, 275-284. 10.1016/j.neuroimage.2017.02.010. MID-IR Health
Raczynska, J.E.; Shabalin, I.G.; Jaskolski, M.; Minor, W.; Wlodawer, A. et al. (2017). Crystal structure of NDM-1 in complex with beta-mercaptoethanol - new refinement. Protein Data Bank: 5n0i. CMCF-BM Health
Raczynska, J.E.; Shabalin, I.G.; Jaskolski, M.; Minor, W.; Wlodawer, A. et al. (2017). Crystal structure of NDM-1 in complex with hydrolyzed meropenem - new refinement. Protein Data Bank: 5n0h. CMCF-BM Health
Ulaganathan, ThirumalaiSelvi; Boniecki, Michal T.; Foran, Elizabeth; Buravenkov, Vitaliy; Mizrachi, Naama et al. (2017). New Ulvan-Degrading Polysaccharide Lyase Family: Structure and Catalytic Mechanism Suggests Convergent Evolution of Active Site Architecture. ACS Chemical Biology 12(5) , 1269-1280. 10.1021/acschembio.7b00126. [PDB: 5uam, 5uas] CMCF-BM Health
Olubamiji, Adeola D.; Zhu, Ning; Chang, Tuanjie; Nwankwo, Chijioke K.; Izadifar, Zohreh et al. (2017). Traditional Invasive and Synchrotron-Based Noninvasive Assessments of Three-Dimensional-Printed Hybrid Cartilage Constructs In Situ. Tissue Engineering - Part C: Methods 23(3) , 156-168. 10.1089/ten.tec.2016.0368. BMIT-ID Health
Gajiwala, K.S.; Ferre, R.A. (2017). Crystal structure of the EGFR kinase domain (L858R, T790M, V948R) in complex with a covalent inhibitor N-[(3R,4R)-4-fluoro-1-{6-[(3-methoxy-1-methyl-1H-pyrazol-4-yl)amino]-9-methyl-9H-purin-2-yl}pyrrolidin-3-yl]propanamide. Protein Data Bank: 5ugc. CMCF-ID Health
Planken, Simon; Behenna, Douglas C.; Nair, Sajiv K.; Johnson, Theodore O.; Nagata, Asako et al. (2017). Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR. Journal of Medicinal Chemistry 60(7) , 3002-3019. 10.1021/acs.jmedchem.6b01894. [PDB: 5ugc] CMCF-ID Health
Gorelik, A.; Liu, F.; Illes, K.; Nagar, B. (2017). Human alkaline sphingomyelinase (alk-SMase, ENPP7, NPP7). Protein Data Bank: 5udy. CMCF-ID Health
Gorelik, A.; Liu, F.; Illes, K.; Nagar, B. (2017). Human alkaline sphingomyelinase (ENPP7) in complex with phosphocholine. Protein Data Bank: 5tcd. CMCF-ID Health
Gorelik, Alexei; Liu, Fangyu; Illes, Katalin; Nagar, Bhushan (2017). Crystal structure of the human alkaline sphingomyelinase provides insights into substrate recognition. Journal of Biological Chemistry 292(17) , 7087-7094. 10.1074/jbc.m116.769273. [PDB: 5tcd, 5udy] CMCF-ID Health
Cook, Jonathan D.; Sultana, Azmiri; Lee, Jeffrey E. (2017). Structure of the infectious salmon anemia virus receptor complex illustrates a unique binding strategy for attachment. Proceedings of the National Academy of Sciences of the United States of America 114(14) , E2929-E2936. 10.1073/pnas.1617993114. [PDB: 5t96, 5t9y] CMCF-ID Health
Loutet, S.A.; Murphy, M.E.P. (2017). Crystal Structure of Burkholderia cenocepacia BcnA. Protein Data Bank: 5ixh. CMCF-ID Health
Loutet, S.A.; Murphy, M.E.P. (2017). Crystal Structure of Burkholderia cenocepacia BcnB. Protein Data Bank: 5ixg. CMCF-ID Health