Publication Beamlines Strategic Pillar
Hamaguchi, Hisao; Amano, Yasushi; Moritomo, Ayako; Shirakami, Shohei; Nakajima, Yutaka et al. (2018). Discovery and structural characterization of peficitinib (ASP015K) as a novel and potent JAK inhibitor. Bioorganic and Medicinal Chemistry 26(18) , 4971-4983. 10.1016/j.bmc.2018.08.005. [PDB: 6aak] CMCF-ID Health
Haji-Ghassemi, Omid; Müller-Loennies, Sven; Saldova, Radka; Muniyappa, Mohankumar; Brade, Lore et al. (2014). Groove-type Recognition of Chlamydiaceae-specific Lipopolysaccharide Antigen by a Family of Antibodies Possessing an Unusual Variable Heavy Chain N-Linked Glycan. Journal of Biological Chemistry 289(24) , 16644-16661. 10.1074/jbc.m113.528224. [PDB: 4m7j, 4m7z, 4m93, 4ma1] CMCF-ID Health
Haji-Ghassemi, Omid; Müller-Loennies, Sven; Rodriguez, Teresa; Brade, Lore; Kosma, Paul et al. (2015). Structural Basis for Antibody Recognition of Lipid A. Journal of Biological Chemistry 290(32) , 19629-19640. 10.1074/jbc.m115.657874. [PDB: 4odt, 4odu, 4odv, 4odw, 4z8f, 4z95] CMCF-ID Health
Haji-Ghassemi, Omid; Müller-Loennies, Sven; Brooks, Cory L.; MacKenzie, C. Roger; Caveney, Nathanael et al. (2018). Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody–Carbohydrate Binding Affinity by an Order of Magnitude. Biochemistry 58(6) , 714-726. 10.1021/acs.biochem.8b00318. [PDB: 6c5h, 6c5i, 6c5j, 6c5k] CMCF-ID Health
Haji-Ghassemi, Omid; Gilbert, Michel; Spence, Jenifer; Schur, Melissa J.; Parker, Matthew J. et al. (2016). Molecular Basis for Recognition of the Cancer Glycobiomarker, LacdiNAc (GalNAc[β1→4]GlcNAc), by Wisteria floribunda Agglutinin. Journal of Biological Chemistry 291(46) , 24085-24095. 10.1074/jbc.m116.750463. [PDB: 5kxb, 5kxc, 5kxd, 5kxe] CMCF-ID Health
Haft, Daniel H.; Pierce, Phillip G.; Mayclin, Stephen J.; Sullivan, Amy; Gardberg, Anna S. et al. (2017). Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors. Scientific Reports 7(1) . 10.1038/srep41074. [PDB: 3t7c] CMCF-ID Health
Hackos, David H.; Lupardus, Patrick J.; Grand, Teddy; Chen, Yelin; Wang, Tzu-Ming et al. (2016). Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function. Neuron 89(5) , 983-999. 10.1016/j.neuron.2016.01.016. [PDB: 5h8h] CMCF-ID Health
Hackett, Mark J.; Sylvain, Nicole J.; Hou, Huishu; Caine, Sally; Alaverdashvili, Mariam et al. (2016). Concurrent Glycogen and Lactate Imaging with FTIR Spectroscopy To Spatially Localize Metabolic Parameters of the Glial Response Following Brain Ischemia. Analytical Chemistry 88(22) , 10949-10956. 10.1021/acs.analchem.6b02588. MID-IR Health
Hackett, Mark J.; Caine, Sally; Liu, Xia; May, Tim E.; Borondics, Ferenc et al. (2015). Development of single-beam wide-field infrared imaging to study sub-cellular neuron biochemistry. Vibrational Spectroscopy 77, 51-59. 10.1016/j.vibspec.2014.12.004. MID-IR Health
Hackett, Mark J.; Borondics, Ferenc; Brown, Devin; Hirschmugl, Carol; Smith, Shari E. et al. (2013). Subcellular Biochemical Investigation of Purkinje Neurons Using Synchrotron Radiation Fourier Transform Infrared Spectroscopic Imaging with a Focal Plane Array Detector. ACS Chemical Neuroscience 4(7) , 1071-1080. 10.1021/cn4000346. MID-IR Health
Guo, Shuaiqi; Stevens, Corey A.; Vance, Tyler D. R.; Olijve, Luuk L. C.; Graham, Laurie A. et al. (2017). Structure of a 1.5-MDa adhesin that binds its Antarctic bacterium to diatoms and ice. Science Advances 3(8) , e1701440. 10.1126/sciadv.1701440. [PDB: 5j6y, 5juh, 5k8g] CMCF-ID Health
Guo, Shuaiqi; Langelaan, David N.; Phippen, Sean W.; Smith, Steven P.; Voets, Ilja K. et al. (2018). Conserved structural features anchor biofilm‐associated RTX –adhesins to the outer membrane of bacteria. FEBS Journal 285(10) , 1812-1826. 10.1111/febs.14441. CMCF-ID Health
Guo, Chuangxing; Linton, Angelica; Jalaie, Mehran; Kephart, Susan; Ornelas, Martha et al. (2013). Discovery of 2-((1H-benzo[d]imidazol-1-yl)methyl)-4H-pyrido[1,2-a]pyrimidin-4-ones as novel PKM2 activators. Bioorganic and Medicinal Chemistry Letters 23(11) , 3358-3363. 10.1016/j.bmcl.2013.03.090. [PDB: 4jpg] CMCF-ID Health
Gruninger, Robert J.; Thibault, John; Capeness, Michael J.; Till, Robert; Mosimann, Steven C. et al. (2014). Structural and Biochemical Analysis of a Unique Phosphatase from Bdellovibrio bacteriovorus Reveals Its Structural and Functional Relationship with the Protein Tyrosine Phosphatase Class of Phytase. PLoS ONE 9(4) , e94403. 10.1371/journal.pone.0094403. [PDB: 4nx8] CMCF-ID Health
Grochulski, Pawel; Fodje, Michel; Labiuk, Shaun; Wysokinski, Tomasz W.; Belev, George et al. (2017). Review of Canadian Light Source facilities for biological applications. Nuclear Instruments and Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms 411, 17-21. 10.1016/j.nimb.2017.01.065. BIOXAS, BMIT-BM, BMIT-ID, CMCF-BM, CMCF-ID, MID-IR Health