Publication Beamlines Strategic Pillar
Lobo, Paolo A.; Kimlicka, Lynn; Tung, Ching-Chieh; Van Petegem, Filip (2011). The Deletion of Exon 3 in the Cardiac Ryanodine Receptor Is Rescued by β Strand Switching. Structure 19(6) , 790-798. 10.1016/j.str.2011.03.016. CMCF-ID Health
Lobo, Paolo Antonio; Van Petegem, Filip (2009). Crystal Structures of the N-Terminal Domains of Cardiac and Skeletal Muscle Ryanodine Receptors: Insights into Disease Mutations. Structure 17(11) , 1505-1514. 10.1016/j.str.2009.08.016. [PDB: 3ila, 3im5, 3im6, 3im7] CMCF-ID Health
Loewen, Peter C.; Carpena, Xavi; Vidossich, Pietro; Fita, Ignacio; Rovira, Carme et al. (2014). An Ionizable Active-Site Tryptophan Imparts Catalase Activity to a Peroxidase Core. Journal of the American Chemical Society 136(20) , 7249-7252. 10.1021/ja502794e. [PDB: 5syh, 5syk] CMCF-ID Health
Loewen, Peter C.; De Silva, P. Malaka; Donald, Lynda J.; Switala, Jacek; Villanueva, Jacylyn et al. (2018). KatG-Mediated Oxidation Leading to Reduced Susceptibility of Bacteria to Kanamycin. ACS Omega 3(4) , 4213-4219. 10.1021/acsomega.8b00356. [PDB: 6b9b] CMCF-ID Health
Loewen, Peter C.; Didychuk, Allison L.; Switala, Jacek; Perez-Luque, Rosa; Fita, Ignacio et al. (2012). Structure ofPisum sativumRubisco with bound ribulose 1,5-bisphosphate. Acta Crystallographica Section F Structural Biology and Crystallization Communications 69(1) , 10-14. 10.1107/s1744309112047549. [PDB: 4hhh, 4mkv] CMCF-ID Health
Loewen, Peter C.; Villanueva, Jacylyn; Switala, Jacek; Donald, Lynda J.; Ivancich, Anabella et al. (2015). Unprecedented access of phenolic substrates to the heme active site of a catalase: Substrate binding and peroxidase-like reactivity ofBacillus pumiluscatalase monitored by X-ray crystallography and EPR spectroscopy. Proteins: Structure. Function and Bioinformatics 83(5) , 853-866. 10.1002/prot.24777. [PDB: 4qol, 4qom, 4qon, 4qoo, 4qop, 4qoq] CMCF-ID Health
Lovering, Andrew L; Lin, Leo Y-C; Sewell, Edward W; Spreter, Thomas; Brown, Eric D et al. (2010). Structure of the bacterial teichoic acid polymerase TagF provides insights into membrane association and catalysis. Nature Structural and Molecular Biology 17(5) , 582-589. 10.1038/nsmb.1819. [PDB: 3l7i, 3l7j, 3l7k, 3l7l, 3l7m] CMCF-ID Health
Lugo, Miguel; Merrill, A. (2015). The Father, Son and Cholix Toxin: The Third Member of the DT Group Mono-ADP-Ribosyltransferase Toxin Family. Toxins 7(8) , 2757-2772. 10.3390/toxins7082757. CMCF-ID Health
Lugo, Miguel R.; Merrill, A. Rod (2015). Pocket analysis of the full-length cholix toxin. An assessment of the structure–dynamics of theapocatalytic domain. Journal of Biomolecular Structure and Dynamics 33(11) , 2452-2468. 10.1080/07391102.2014.1000972. CMCF-ID Health
Lugo, Miguel R.; Ravulapalli, Ravikiran; Dutta, Debajyoti; Rod Merrill, A. (2016). Structural variability of C3larvin toxin. Intrinsic dynamics of the α/β fold of the C3-like group of mono-ADP-ribosyltransferase toxins. Journal of Biomolecular Structure and Dynamics , 2537-2560. 10.1080/07391102.2015.1123189. [PDB: 5dzq] CMCF-ID Health
Lyons, Bronwyn; Lugo, Miguel R.; Carlin, Stephanie; Lidster, Taylor; Merrill, A. Rod et al. (2018). Characterization of the catalytic signature of Scabin toxin, a DNA-targeting ADP-ribosyltransferase. Biochemical Journal 475(1) , 225-245. 10.1042/bcj20170818. [PDB: 5tlb, 5uvq, 6apy] CMCF-ID Health
Lyons, Bronwyn; Ravulapalli, Ravikiran; Lanoue, Jason; Lugo, Miguel R.; Dutta, Debajyoti et al. (2016). Scabin, a Novel DNA-acting ADP-ribosyltransferase from Streptomyces scabies. Journal of Biological Chemistry 291(21) , 11198-11215. 10.1074/jbc.m115.707653. [PDB: 5daz, 5ewk, 5ewy] CMCF-ID Health
MacFarlane, Ainsley A.; Orriss, George; Okun, Natalie; Meier, Markus; Klonisch, Thomas et al. (2012). The Pentameric Channel of COMPcc in Complex with Different Fatty Acids. PLoS ONE 7(11) , e48130. 10.1371/journal.pone.0048130. [PDB: 3v2n, 3v2p, 3v2q] CMCF-ID Health
Machuqueiro, Miguel; Victor, Bruno; Switala, Jacek; Villanueva, Jacylyn; Rovira, Carme et al. (2017). The Catalase Activity of Catalase-Peroxidases Is Modulated by Changes in the pKa of the Distal Histidine. Biochemistry 56(17) , 2271-2281. 10.1021/acs.biochem.6b01276. [PDB: 5kq0, 5kq2, 5kq3, 5kq6, 5kqh, 5kqi, 5kqk, 5ksf, 5ksk, 5syu, 5syv, 5syw, 5txq, 5v4o, 5v53] CMCF-ID Materials
Mahoney, Sarah J.; Narayan, Sridhar; Molz, Lisa; Berstler, Lauren A.; Kang, Seong A. et al. (2018). A small molecule inhibitor of Rheb selectively targets mTORC1 signaling. Nature Communications 9(1) . 10.1038/s41467-018-03035-z. [PDB: 6bt0] CMCF-ID Health