Publication Beamlines Strategic Pillar
Riggs, Jennifer R.; Nagy, Mark; Elsner, Jan; Erdman, Paul; Cashion, Dan et al. (2017). The Discovery of a Dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) Inhibitor for the Treatment of Triple Negative Breast Cancer Initiated from a Phenotypic Screen. Journal of Medicinal Chemistry 60(21) , 8989-9002. 10.1021/acs.jmedchem.7b01223. [PDB: 6b4w] CMCF-ID Health
Roach, Elyse J.; Kimber, Matthew S.; Khursigara, Cezar M. (2014). Crystal Structure and Site-directed Mutational Analysis Reveals Key Residues Involved in Escherichia coli ZapA Function. Journal of Biological Chemistry 289(34) , 23276-23286. 10.1074/jbc.m114.561928. [PDB: 4p1m] CMCF-ID Materials
Roach, Elyse J.; Wroblewski, Charles; Seidel, Laura; Berezuk, Alison M.; Brewer, Dyanne et al. (2016). Structure and Mutational Analyses of Escherichia coli ZapD Reveal Charged Residues Involved in FtsZ Filament Bundling. Journal of Bacteriology 198(11) , 1683-1693. 10.1128/jb.00969-15. [PDB: 5dko] CMCF-ID Health
Robb, Melissa; Robb, Craig S.; Higgins, Melanie A.; Hobbs, Joanne K.; Paton, James C. et al. (2015). A Second β-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans. Journal of Biological Chemistry 290(52) , 30888-30900. 10.1074/jbc.m115.688630. [PDB: 5a6a, 5a6b, 5a6k, 5ac5] CMCF-ID Health
Roberts, Joseph N. (2011). Identification and characterization of DyP peroxidases from Rhodococcus jostii RHA1. Supervisor: Eltis, Lindsay. British Columbia, Canada: University of British Columbia. http://hdl.handle.net/2429/31830. CMCF-ID Materials
Roberts, Joseph N.; Singh, Rahul; Grigg, Jason C.; Murphy, Michael E. P.; Bugg, Timothy D. H. et al. (2011). Characterization of Dye-Decolorizing Peroxidases from Rhodococcus jostii RHA1. Biochemistry 50(23) , 5108-5119. 10.1021/bi200427h. [PDB: 3qnr] CMCF-ID Health
Ruane, K.M.; Rangarajan, E.S.; Proteau, A.; Schrag, J.D.; Cygler, M. et al. (2011). Crystal structure of NanS. Protein Data Bank: 3pt5. CMCF-ID Agriculture
Ruane, K.M.; Shi, R.; Cygler, M.; Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) (2011). Crystal Structure of SPY. Protein Data Bank: 3o39. CMCF-ID Agriculture
Rutaganira, Florentine U.; Fowler, Melissa L.; McPhail, Jacob A.; Gelman, Michael A.; Nguyen, Khanh et al. (2016). Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβ. Journal of Medicinal Chemistry 59(5) , 1830-1839. 10.1021/acs.jmedchem.5b01311. [PDB: 5euq] CMCF-ID Health
Sachdev Sidhu; Linda Beatty; Andreas Ernst (2012). Specific active site inhibitors of enzymes or substrate binding partners and methods of producing same. Patent Number: CA2807774A1. CMCF-ID Health
Sack, John S.; Gao, Mian; Kiefer, Susan E.; Myers, Joseph E.; Newitt, John A. et al. (2016). Crystal structure of microtubule affinity-regulating kinase 4 catalytic domain in complex with a pyrazolopyrimidine inhibitor. Acta Crystallographica Section F:Structural Biology Communications 72(2) , 129-134. 10.1107/s2053230x15024747. [PDB: 5es1] CMCF-ID Health
Sack, J.S. (2017). CRYSTAL STRUCTURE OF JAK3 KINASE DOMAIN IN COMPLEX WITH A PYRROLOPYRIDAZINE INHIBITOR. Protein Data Bank: 5vo6. CMCF-ID Health
Sack, J.S. (2015). CRYSTAL STRUCTURE OF MICROTUBULE AFFINITY-REGULATING KINASE 4 CATALYTIC DOMAIN IN COMPLEX WITH A PYRAZOLOPYRIMIDINE INHIBITOR. Protein Data Bank: 5es1. CMCF-ID Health
Sack, J.S. (2015). CRYSTAL STRUCTURE OF JANUS KINASE 2 IN COMPLEX WITH N,N-DICYCLOPROPYL-10-ETHYL-7-[(3-METHOXYPROPYL)AMINO] -3-METHYL-3,5,8,10-TETRAAZATRICYCLO[7.3.0.0,6] DODECA-1(9),2(6),4,7,11-PENTAENE-11-CARBOXAMIDE. Protein Data Bank: 5cf8. CMCF-ID Health
Sack, J.S. (2014). Crystal structure of JAK3 kinase domain in complex with a pyrrolopyridazine carboxamide inhibitor. Protein Data Bank: 4rio. CMCF-ID Health