| Park, J.; Gobeil, S.; Pelletier, J.N.; Berghuis, A.M. (2015). Crystal structure of chimeric beta-lactamase cTEM-19m at 1.2 angstrom resolution. Protein Data Bank: 4r4r. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Park, J.; Gobeil, S.; Pelletier, J.N.; Berghuis, A.M. (2015). Crystal structures of chimeric beta-lactamase cTEM-19m showing different conformations. Protein Data Bank: 4qy5. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Park, J.; Gobeil, S.; Pelletier, J.N.; Berghuis, A.M. (2013). Crystal structure of chimeric beta-lactamase cTEM-17m. Protein Data Bank: 4id4. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Park, J.; Gobeil, S.; Pelletier, J.N.; Berghuis, A.M. (2015). Crystal structures of chimeric beta-lactamase cTEM-19m. Protein Data Bank: 4r4s. |
CMCF-ID |
PDB Deposition |
|
| Park, J.; Gobeil, S.; Pelletier, J.N.; Berghuis, A.M. (2015). Crystal structures of chimeric beta-lactamase cTEM-19m showing different conformations. Protein Data Bank: 4qy6. |
CMCF-ID |
PDB Deposition |
|
| Park, J.; De Schutter, J.W.; Tsantrizos, Y.S.; Berghuis, A.M. (2014). Crystal structure of human FPPS in complex with magnesium, JDS05120, and sulfate. Protein Data Bank: 4nfj. |
CMCF-ID |
PDB Deposition |
Health |
| Park, J.; De Schutter, J.W.; Tsantrizos, Y.S.; Berghuis, A.M. (2014). Crystal structure of human FPPS in complex with magnesium and JDS05120. Protein Data Bank: 4nfi. |
CMCF-ID |
PDB Deposition |
Health |
| Park, J.; De schutter, J.W.; Tsantrizos, Y.S.; Berghuis, A.M. (2014). Crystal structure of human FPPS in complex with nickel, JDS05120, and sulfate. Protein Data Bank: 4nfk. |
CMCF-ID |
PDB Deposition |
Health |
| Park, J.; Berghuis, A.M. (2016). Crystal structure of human FPPS in complex with three magnesium ions. Protein Data Bank: 4xqt. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Park, J.; Berghuis, A.M. (2016). Crystal structure of human FPPS in complex with one magnesium ion. Protein Data Bank: 4xqs. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Park, J.; Berghuis, A.M. (2016). Crystal structure of unliganded human FPPS at 2.15 angstrom resolution. Protein Data Bank: 4xqr. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Park, Jaeok; Zielinski, Michal; Magder, Alexandr; Tsantrizos, Youla S.; Berghuis, Albert M. et al. (2017). Human farnesyl pyrophosphate synthase is allosterically inhibited by its own product. Nature Communications 8(1) . 10.1038/ncomms14132. [PDB: 5ja0] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Park, Jaeok; Rodionov, Dmitry; De Schutter, Joris W.; Lin, Yih-Shyan; Tsantrizos, Youla S. et al. (2017). Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase. PLoS ONE 12(10) , e0186447. 10.1371/journal.pone.0186447. [PDB: 4nfi, 4nfj, 4nfk] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Park, Jaeok; Lin, Yih-Shyan; Tsantrizos, Youla S.; Berghuis, Albert M. (2014). Structure of human farnesyl pyrophosphate synthase in complex with an aminopyridine bisphosphonate and two molecules of inorganic phosphate. Acta Crystallographica Section F Structural Biology and Crystallization Communications 70(3) , 299-304. 10.1107/s2053230x14002106. [PDB: 4lfv] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Park, Jaeok; Leung, Chun Yuen; Matralis, Alexios N.; Lacbay, Cyrus M.; Tsakos, Michail et al. (2017). Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase. Journal of Medicinal Chemistry 60(5) , 2119-2134. 10.1021/acs.jmedchem.6b01888. [PDB: 5juz, 5jv1] |
CMCF-ID |
Peer-Reviewed Article |
Health |