| Gorelik, A.; Illes, K.; Heinz, L.X.; Superti-Furga, G.; Nagar, B. et al. (2016). Open form of murine Acid Sphingomyelinase. Protein Data Bank: 5fib. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Gorelik, A.; Illes, K.; Heinz, L.X.; Superti-Furga, G.; Nagar, B. et al. (2016). Closed form of murine Acid Sphingomyelinase in complex with bisphosphonate inhibitor AbPA. Protein Data Bank: 5fi9. |
CMCF-BM |
PDB Deposition |
Agriculture |
| Gorelik, A.; Illes, K.; Heinz, L.X.; Superti-Furga, G.; Nagar, B. et al. (2016). Catalytic domain of murine Acid Sphingomyelinase (ASMase, ASM, SMPD1). Protein Data Bank: 5hqn. |
CMCF-ID |
PDB Deposition |
Health |
| Gorelik, A.; Illes, K.; Superti-Furga, G.; Nagar, B. (2016). Murine SMPDL3A in complex with AMP. Protein Data Bank: 5fcb. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Gorelik, A.; Illes, K.; Superti-Furga, G.; Nagar, B. (2016). Murine SMPDL3A in complex with sulfate (tetragonal). Protein Data Bank: 5fc7. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Gorelik, A.; Illes, K.; Superti-Furga, G.; Nagar, B. (2016). Murine SMPDL3A in complex with ADP analog AMPCP. Protein Data Bank: 5fc6. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Gorelik, A.; Illes, K.; Superti-Furga, G.; Nagar, B. (2016). Murine SMPDL3A in complex with sulfate. Protein Data Bank: 5fc1. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Gorelik, A.; Illes, K.; Superti-Furga, G.; Nagar, B. (2016). Murine SMPDL3A in presence of excess zinc. Protein Data Bank: 5fca. |
CMCF-BM |
PDB Deposition |
Agriculture |
| Gorelik, Alexei; Heinz, Leonhard X.; Illes, Katalin; Superti-Furga, Giulio; Nagar, Bhushan et al. (2016). Crystal Structure of the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3B Provides Insights into Determinants of Substrate Specificity. Journal of Biological Chemistry 291(46) , 24054-24064. 10.1074/jbc.m116.755801. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Gorelik, Alexei; Illes, Katalin; Heinz, Leonhard X.; Superti-Furga, Giulio; Nagar, Bhushan et al. (2016). Crystal structure of mammalian acid sphingomyelinase. Nature Communications 7(1) . 10.1038/ncomms12196. [PDB: 5fi9, 5fib, 5fic, 5hqn] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Gorelik, Alexei; Illes, Katalin; Superti-Furga, Giulio; Nagar, Bhushan (2016). Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A. Journal of Biological Chemistry 291(12) , 6376-6385. 10.1074/jbc.m115.711085. [PDB: 5fc1, 5fc6, 5fc7, 5fca, 5fcb] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Gorelik, Alexei; Liu, Fangyu; Illes, Katalin; Nagar, Bhushan (2017). Crystal structure of the human alkaline sphingomyelinase provides insights into substrate recognition. Journal of Biological Chemistry 292(17) , 7087-7094. 10.1074/jbc.m116.769273. [PDB: 5tcd, 5udy] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Gorelik, Alexei; Randriamihaja, Antsa; Illes, Katalin; Nagar, Bhushan (2017). A key tyrosine substitution restricts nucleotide hydrolysis by the ectoenzyme
NPP
5. FEBS Journal 284(21) , 3718-3726. 10.1111/febs.14266. [PDB: 5vem, 5ven] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Gorelik, A.; Liu, F.; Illes, K.; Nagar, B. (2017). Human alkaline sphingomyelinase (alk-SMase, ENPP7, NPP7). Protein Data Bank: 5udy. |
CMCF-ID |
PDB Deposition |
Health |
| Gorelik, A.; Liu, F.; Illes, K.; Nagar, B. (2017). Human alkaline sphingomyelinase (ENPP7) in complex with phosphocholine. Protein Data Bank: 5tcd. |
CMCF-ID |
PDB Deposition |
Health |