Publication Beamlines Strategic Pillar
Gorelik, Alexei; Heinz, Leonhard X.; Illes, Katalin; Superti-Furga, Giulio; Nagar, Bhushan et al. (2016). Crystal Structure of the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3B Provides Insights into Determinants of Substrate Specificity. Journal of Biological Chemistry 291(46) , 24054-24064. 10.1074/jbc.m116.755801. CMCF-ID Health
Gorelik, Alexei; Illes, Katalin; Heinz, Leonhard X.; Superti-Furga, Giulio; Nagar, Bhushan et al. (2016). Crystal structure of mammalian acid sphingomyelinase. Nature Communications 7(1) . 10.1038/ncomms12196. [PDB: 5fi9, 5fib, 5fic, 5hqn] CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Illes, Katalin; Heinz, Leonhard X.; Superti-Furga, Giulio; Nagar, Bhushan et al. (2016). Crystal structure of mammalian acid sphingomyelinase. Nature Communications 7(1) . 10.1038/ncomms12196. [PDB: 5fi9, 5fib, 5fic, 5hqn] CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Illes, Katalin; Superti-Furga, Giulio; Nagar, Bhushan (2016). Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A. Journal of Biological Chemistry 291(12) , 6376-6385. 10.1074/jbc.m115.711085. [PDB: 5fc1, 5fc6, 5fc7, 5fca, 5fcb] CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Illes, Katalin; Superti-Furga, Giulio; Nagar, Bhushan (2016). Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A. Journal of Biological Chemistry 291(12) , 6376-6385. 10.1074/jbc.m115.711085. [PDB: 5fc1, 5fc6, 5fc7, 5fca, 5fcb] CMCF-BM, CMCF-ID Health
Gorelik, Alexei; Liu, Fangyu; Illes, Katalin; Nagar, Bhushan (2017). Crystal structure of the human alkaline sphingomyelinase provides insights into substrate recognition. Journal of Biological Chemistry 292(17) , 7087-7094. 10.1074/jbc.m116.769273. [PDB: 5tcd, 5udy] CMCF-ID Health
Gorelik, Alexei; Randriamihaja, Antsa; Illes, Katalin; Nagar, Bhushan (2017). A key tyrosine substitution restricts nucleotide hydrolysis by the ectoenzyme NPP 5. FEBS Journal 284(21) , 3718-3726. 10.1111/febs.14266. [PDB: 5vem, 5ven] CMCF-ID Health
Gorelik, A.; Liu, F.; Illes, K.; Nagar, B. (2017). Human alkaline sphingomyelinase (alk-SMase, ENPP7, NPP7). Protein Data Bank: 5udy. CMCF-ID Health
Gorelik, A.; Liu, F.; Illes, K.; Nagar, B. (2017). Human alkaline sphingomyelinase (ENPP7) in complex with phosphocholine. Protein Data Bank: 5tcd. CMCF-ID Health
Gorelik, A.; Randriamihaja, A.; Illes, K.; Nagar, B. (2017). Murine ectonucleotide pyrophosphatase / phosphodiesterase 5 (ENPP5, NPP5). Protein Data Bank: 5ven. CMCF-ID Health
Gorelik, A.; Randriamihaja, A.; Illes, K.; Nagar, B. (2017). Human ectonucleotide pyrophosphatase / phosphodiesterase 5 (ENPP5, NPP5). Protein Data Bank: 5vem. CMCF-ID Health
Gould, Alister D. (2012). ATPase Regulation in the Maltose Transporter. Supervisor: Shilton, Brian. Ontario, Canada: University of Western Ontario. http://ir.lib.uwo.ca/etd/374. CMCF-ID Health
Gould, Alister D.; Shilton, Brian H. (2010). Studies of the Maltose Transport System Reveal a Mechanism for Coupling ATP Hydrolysis to Substrate Translocation without Direct Recognition of Substrate. Journal of Biological Chemistry 285(15) , 11290-11296. 10.1074/jbc.m109.089078. [PDB: 3hpi, 3kjt] CMCF-ID Health
Grandin, Mélodie; Meier, Markus; Delcros, Jean Guy; Nikodemus, Denise; Reuten, Raphael et al. (2016). Structural Decoding of the Netrin-1/UNC5 Interaction and its Therapeutical Implications in Cancers. Cancer Cell 29(2) , 173-185. 10.1016/j.ccell.2016.01.001. [PDB: 4ove] CMCF-BM Health
Greasley, S.E.; Hickey, M.; Phonephaly, H.; Cronin, C. (2013). 2-((1H-benzo[d]imidazol-1-yl)methyl)-4H-pyrido[1,2-a]pyrimidin-4-ones as Novel PKM2 Activators. Protein Data Bank: 4jpg. CMCF-ID Health