Ndubaku, Chudi O.; Crawford, James J.; Drobnick, Joy; Aliagas, Ignacio; Campbell, David et al. (2015). Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pKa Polar Moiety. ACS Medicinal Chemistry Letters 6(12) , 1241-1246. 10.1021/acsmedchemlett.5b00398. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Ndubaku, Chudi O.; Crawford, Terry D.; Chen, Huifen; Boggs, Jason W.; Drobnick, Joy et al. (2015). Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis. ACS Medicinal Chemistry Letters 6(8) , 913-918. 10.1021/acsmedchemlett.5b00174. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Niu, Chunying; Yin, Jiang; Cherney, Maia M.; James, Michael N. G. (2011). Expression, purification and preliminary crystallographic analysis of Rv2247, the β subunit of acyl-CoA carboxylase (ACCD6) from Mycobacterium tuberculosis. Acta Crystallographica Section F Structural Biology and Crystallization Communications 67(12) , 1637-1640. 10.1107/s1744309111038413. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Noach, Ilit; Ficko-Blean, Elizabeth; Pluvinage, Benjamin; Stuart, Christopher; Jenkins, Meredith L. et al. (2017). Recognition of protein-linked glycans as a determinant of peptidase activity. Proceedings of the National Academy of Sciences of the United States of America 114(5) , E679-E688. 10.1073/pnas.1615141114. [PDB: 5kd5, 5kd8, 5kdn, 5kdu, 5kdv, 5kdw, 5kdx] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Noach, Ilit; Ficko-Blean, Elizabeth; Pluvinage, Benjamin; Stuart, Christopher; Jenkins, Meredith L. et al. (2017). Recognition of protein-linked glycans as a determinant of peptidase activity. Proceedings of the National Academy of Sciences of the United States of America 114(5) , E679-E688. 10.1073/pnas.1615141114. [PDB: 5kd5, 5kd8, 5kdn, 5kdu, 5kdv, 5kdw, 5kdx] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Noach, Ilit; Pluvinage, Benjamin; Laurie, Cassandra; Abe, Kento T.; Alteen, Matthew G. et al. (2016). The Details of Glycolipid Glycan Hydrolysis by the Structural Analysis of a Family 123 Glycoside Hydrolase from Clostridium perfringens. Journal of Molecular Biology 428(16) , 3253-3265. 10.1016/j.jmb.2016.03.020. [PDB: 5fqe, 5fqg, 5fqh, 5fr0] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Noguchi, Masato; Nomura, Akihiro; Murase, Ken; Doi, Satoki; Yamaguchi, Keishi et al. (2017). Ternary complex of human RORγ ligand-binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment. Genes to Cells 22(6) , 535-551. 10.1111/gtc.12494. [PDB: 5x8q] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Norman, Mark H.; Andrews, Kristin L.; Bo, Yunxin Y.; Booker, Shon K.; Caenepeel, Sean et al. (2012). Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511. Journal of Medicinal Chemistry 55(17) , 7796-7816. 10.1021/jm300846z. [PDB: 4flh] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Oh, Angela; Ho, Yen-Ching; Zak, Mark; Liu, Yongbo; Chen, Xukun et al. (2014). Structural and Biochemical Analyses of the Catalysis and Potency Impact of Inhibitor Phosphoribosylation by Human Nicotinamide Phosphoribosyltransferase. ChemBioChem 15(8) , 1121-1130. 10.1002/cbic.201402023. [PDB: 4o0z, 4o10] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Olkowski, A. A.; Laarveld, B.; Wojnarowicz, C.; Chirino-Trejo, M.; Chapman, D. et al. (2011). Biochemical and physiological weaknesses associated with the pathogenesis of femoral bone degeneration in broiler chickens. Avian Pathology 40(6) , 639-650. 10.1080/03079457.2011.626017. |
BMIT-BM, MID-IR |
Peer-Reviewed Article |
Health |
Olkowski, A. A.; Laarveld, B.; Wojnarowicz, C.; Chirino-Trejo, M.; Chapman, D. et al. (2011). Biochemical and physiological weaknesses associated with the pathogenesis of femoral bone degeneration in broiler chickens. Avian Pathology 40(6) , 639-650. 10.1080/03079457.2011.626017. |
BMIT-BM, MID-IR |
Peer-Reviewed Article |
Health |
Olubamiji, Adeola D.; Zhu, Ning; Chang, Tuanjie; Nwankwo, Chijioke K.; Izadifar, Zohreh et al. (2017). Traditional Invasive and Synchrotron-Based Noninvasive Assessments of Three-Dimensional-Printed Hybrid Cartilage Constructs In Situ. Tissue Engineering - Part C: Methods 23(3) , 156-168. 10.1089/ten.tec.2016.0368. |
BMIT-ID |
Peer-Reviewed Article |
Health |
Orriss, George L.; Patel, Trushar R.; Sorensen, John; Stetefeld, Jörg (2009). Absence of a catalytic water confers resistance to the neurotoxin gabaculine. FASEB Journal 24(2) , 404-414. 10.1096/fj.09-138297. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Osman, Khan Tanjid; Du, Liqin; He, Yujiong; Luo, Yu (2009). Crystal Structure of Bacillus cereus d-Alanyl Carrier Protein Ligase (DltA) in Complex with ATP. Journal of Molecular Biology 388(2) , 345-355. 10.1016/j.jmb.2009.03.040. [PDB: 3fcc] |
CMCF-ID |
Peer-Reviewed Article |
Health |
O'Sullivan, Valerie J.; Barrette-Ng, Isabelle; Hommema, Eric; Hermanson, Greg T.; Schofield, Mark et al. (2012). Development of a Tetrameric Streptavidin Mutein with Reversible Biotin Binding Capability: Engineering a Mobile Loop as an Exit Door for Biotin. PLoS ONE 7(4) , e35203. 10.1371/journal.pone.0035203. |
CMCF-ID |
Peer-Reviewed Article |
Health |