Publication Beamlines Strategic Pillar
Shi, Rong; Proteau, Ariane; Villarroya, Magda; Moukadiri, Ismaïl; Zhang, Linhua et al. (2010). Structural Basis for Fe–S Cluster Assembly and tRNA Thiolation Mediated by IscS Protein–Protein Interactions. PLoS Biology 8(4) , e1000354. 10.1371/journal.pbio.1000354. [PDB: 3lvl] CMCF-ID Health
Hou, Jinzhao; Townson, Sharon A.; Kovalchin, Joseph T.; Masci, Allyson; Kiner, Olga et al. (2013). Design of a superior cytokine antagonist for topical ophthalmic use. Proceedings of the National Academy of Sciences of the United States of America 110(10) , 3913-3918. 10.1073/pnas.1217996110. [PDB: 4gaf, 4gai] CMCF-ID Health
Abbas, Yazan M.; Pichlmair, Andreas; Górna, Maria W.; Superti-Furga, Giulio; Nagar, Bhushan et al. (2013). Structural basis for viral 5′-PPP-RNA recognition by human IFIT proteins. Nature 494(7435) , 60-64. 10.1038/nature11783. [PDB: 4hoq, 4hou] CMCF-ID Health
Mizuno, Yutaka; Moorhead, Greg B.G.; Ng, Kenneth K.-S. (2007). Structural Basis for the Regulation of N-Acetylglutamate Kinase by PII in Arabidopsis thaliana. Journal of Biological Chemistry 282(49) , 35733-35740. 10.1074/jbc.m707127200. [PDB: 2rd5] CMCF-ID Health
Zheng, Xiaozhang; Baumeister, Timm; Buckmelter, Alexandre J.; Caligiuri, Maureen; Clodfelter, Karl H. et al. (2014). Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors. Bioorganic and Medicinal Chemistry Letters 24(1) , 337-343. 10.1016/j.bmcl.2013.11.006. [PDB: 4lww] CMCF-ID Health
Lewis, Melissa; Meza-Avina, Maria Elena; Wei, Lianhu; Crandall, Ian E.; Bello, Angelica Mara et al. (2011). Novel Interactions of Fluorinated Nucleotide Derivatives Targeting Orotidine 5′-Monophosphate Decarboxylase. Journal of Medicinal Chemistry 54(8) , 2891-2901. 10.1021/jm101642g. [PDB: 3mo7] CMCF-ID Health
Sarhan, Maen F.; Tung, Ching-Chieh; Van Petegem, Filip; Ahern, Christopher A. (2012). Crystallographic basis for calcium regulation of sodium channels. Proceedings of the National Academy of Sciences of the United States of America 109(9) , 3558-3563. 10.1073/pnas.1114748109. [PDB: 4djc] CMCF-ID Health
Johnson, Ted W.; Richardson, Paul F.; Bailey, Simon; Brooun, Alexei; Burke, Benjamin J. et al. (2014). Discovery of (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations. Journal of Medicinal Chemistry 57(11) , 4720-4744. 10.1021/jm500261q. [PDB: 4ctb] CMCF-ID Health
Grondin, Julie M.; Duan, Da; Kirlin, Alyssa C.; Abe, Kento T.; Chitayat, Seth et al. (2017). Diverse modes of galacto-specific carbohydrate recognition by a family 31 glycoside hydrolase from Clostridium perfringens. PLoS ONE 12(2) , e0171606. 10.1371/journal.pone.0171606. CLS-APS, CMCF-BM Health
McDougall, Matthew; Francisco, Olga; Harder-Viddal, Candice; Roshko, Roy; Meier, Markus et al. (2017). Archaea S-layer nanotube from a “black smoker” in complex with cyclo-octasulfur (S 8 ) rings. Proteins: Structure. Function and Bioinformatics 85(12) , 2209-2216. 10.1002/prot.25385. CMCF-BM Health
Kuatsjah, Eugene; Chan, Anson C.K.; Kobylarz, Marek J.; Murphy, Michael E.P.; Eltis, Lindsay D. et al. (2017). The bacterial meta-cleavage hydrolase LigY belongs to the amidohydrolase superfamily, not to the α/β-hydrolase superfamily. Journal of Biological Chemistry 292(44) , 18290-18302. 10.1074/jbc.m117.797696. [PDB: 5vn5] CMCF-BM Health
Smirnova, Ekaterina; Kwan, Jamie J.; Siu, Ryan; Gao, Xin; Zoidl, Georg et al. (2016). A new mode of SAM domain mediated oligomerization observed in the CASKIN2 neuronal scaffolding protein. Cell Communication and Signaling 14(1) , 17. 10.1186/s12964-016-0140-3. [PDB: 5l1m] CMCF-BM Health
Solomonson, Matthew; Setiaputra, Dheva; Makepeace, Karl A.T.; Lameignere, Emilie; Petrotchenko, Evgeniy V. et al. (2015). Structure of EspB from the ESX-1 Type VII Secretion System and Insights into its Export Mechanism. Structure 23(3) , 571-583. 10.1016/j.str.2015.01.002. [PDB: 4wj1, 4wj2] CMCF-BM Health
Pawluk, April; Shah, Megha; Mejdani, Marios; Calmettes, Charles; Moraes, Trevor F. et al. (2017). Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein. mBio 8(6) , e01751-17. 10.1128/mbio.01751-17. [PDB: 6arz, 6as4] CMCF-BM Health
Sychantha, David; Little, Dustin J; Chapman, Robert N; Boons, Geert-Jan; Robinson, Howard et al. (2017). PatB1 is an O-acetyltransferase that decorates secondary cell wall polysaccharides. Nature Chemical Biology 14(1) , 79-85. 10.1038/nchembio.2509. [PDB: 5v8e] CMCF-BM Health