Publication Beamlines Strategic Pillar
Wu, Hong; Siarheyeva, Alena; Zeng, Hong; Lam, Robert; Dong, Aiping et al. (2013). Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2. FEBS Letters 587(23) , 3859-3868. 10.1016/j.febslet.2013.10.020. [PDB: 3s8p] CMCF-ID Health
Wu, Hong; Zeng, Hong; Dong, Aiping; Li, Fengling; He, Hao et al. (2013). Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations. PLoS ONE 8(12) , e83737. 10.1371/journal.pone.0083737. [PDB: 4mi0] CMCF-ID Health
Wu, Hong; Zeng, Hong; Lam, Robert; Tempel, Wolfram; Amaya, Maria F. et al. (2011). Structural and Histone Binding Ability Characterizations of Human PWWP Domains. PLoS ONE 6(6) , e18919. 10.1371/journal.pone.0018919. [PDB: 3llr, 3lyi] CMCF-ID Health
Wu; Tao (2012). Structural and Functional Studies of the Core Splicing Factor Prp8. Supervisor: MacMillan, Andrew. Alberta, Canada: University of Alberta. https://doi.org/10.7939/R3JD4Q10M. CMCF-ID Agriculture
Wu, Wen-Lian; Hao, Jinsong; Domalski, Martin; Burnett, Duane A.; Pissarnitski, Dmitri et al. (2016). Discovery of Novel Tricyclic Heterocycles as Potent and Selective DPP-4 Inhibitors for the Treatment of Type 2 Diabetes. ACS Medicinal Chemistry Letters 7(5) , 498-501. 10.1021/acsmedchemlett.6b00027. [PDB: 5i7u] CMCF-ID Health
Wu, Yong-Jin; Guernon, Jason; Shi, Jianliang; Marcin, Lawrence; Higgins, Mendi et al. (2016). Discovery of S3-Truncated, C-6 Heteroaryl Substituted Aminothiazine Ī²-Site APP Cleaving Enzyme-1 (BACE1) Inhibitors. Journal of Medicinal Chemistry 59(18) , 8593-8600. 10.1021/acs.jmedchem.6b01012. [PDB: 5kr8] CMCF-ID Health
Wyrzucki, Arkadiusz; Dreyfus, Cyrille; Kohler, Ines; Steck, Marco; Wilson, Ian A. et al. (2014). Alternative Recognition of the Conserved Stem Epitope in Influenza A Virus Hemagglutinin by a V H 3-30-Encoded Heterosubtypic Antibody. Journal of Virology 88(12) , 7083-7092. 10.1128/jvi.00178-14. [PDB: 4py8] CMCF-ID Health
Xie, J.; Chen, Y.; Wei, X.; Kozlov, G.; Gehring, K. et al. (2017). X-Ray crystallography structure of the parallel stranded duplex formed by 5-rA5-dA-rA5. Protein Data Bank: 5vxq. CMCF-ID Agriculture
Xiong, Yumei; Walker, Kenneth; Min, Xiaoshan; Hale, Clarence; Tran, Thanhvien et al. (2017). Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys. Science Translational Medicine 9(412) , eaan8732. 10.1126/scitranslmed.aan8732. [PDB: 5vt2] CMCF-ID Health
Xu, Chao; Bian, Chuanbing; Yang, Wei; Galka, Marek; Ouyang, Hui et al. (2010). Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2). Proceedings of the National Academy of Sciences of the United States of America 107(45) , 19266-19271. 10.1073/pnas.1008937107. CMCF-ID Health
Xu, C.; Tempel, W.; Cerovina, T.; El Bakkouri, M.; Bountra, C. et al. (2012). Crystal structure of KANK2 ankyrin repeats. Protein Data Bank: 4hbd. CMCF-ID Agriculture
Xu, C.; Tempel, W.; He, H.; Wu, X.; Seitova, A. et al. (2014). Crystal structure of TBL1XR1 WD40 repeats. Protein Data Bank: 4lg9. CMCF-ID Agriculture
Xu, Yufei; Xu, Chao; Kato, Akiko; Tempel, Wolfram; Abreu, JoseĀ Garcia et al. (2012). Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development. Cell 151(6) , 1200-1213. 10.1016/j.cell.2012.11.014. [PDB: 4hp1, 4hp3] CMCF-ID Health
Yachnin, B.J.; Berghuis, A.M. (2014). Epsilon-caprolactone-bound crystal structure of cyclohexanone monooxygenase in the Tight conformation. Protein Data Bank: 4rg3. CMCF-ID Agriculture
Yachnin, Brahm J.; McEvoy, Michelle B.; MacCuish, Roderick J. D.; Morley, Krista L.; Lau, Peter C. K. et al. (2014). Lactone-Bound Structures of Cyclohexanone Monooxygenase Provide Insight into the Stereochemistry of Catalysis. ACS Chemical Biology 9(12) , 2843-2851. 10.1021/cb500442e. [PDB: 4rg3] CMCF-ID Health