Publication Beamlines Strategic Pillar
Skovpen, Yulia V.; Conly, Cuylar J. T.; Sanders, David A. R.; Palmer, David R. J. (2016). Biomimetic Design Results in a Potent Allosteric Inhibitor of Dihydrodipicolinate Synthase from Campylobacter jejuni. Journal of the American Chemical Society 138(6) , 2014-2020. 10.1021/jacs.5b12695. [PDB: 5f1u, 5f1v] CMCF-ID Health
Sobhanifar, Solmaz; Worrall, Liam J.; King, Dustin T.; Wasney, Gregory A.; Baumann, Lars et al. (2016). Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid β-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathogens 12(12) , e1006067. 10.1371/journal.ppat.1006067. [PDB: 5tzi, 5tzj, 5u02] CMCF-BM, CMCF-ID Health
Strushkevich, Natallia; Gilep, Andrei A.; Shen, Limin; Arrowsmith, Cheryl H.; Edwards, Aled M. et al. (2013). Structural Insights into Aldosterone Synthase Substrate Specificity and Targeted Inhibition. Molecular Endocrinology 27(2) , 315-324. 10.1210/me.2012-1287. [PDB: 4dvq] CMCF-ID Health
Strushkevich, Natallia; Usanov, Sergey A.; Park, Hee-Won (2010). Structural Basis of Human CYP51 Inhibition by Antifungal Azoles. Journal of Molecular Biology 397(4) , 1067-1078. 10.1016/j.jmb.2010.01.075. [PDB: 3jus] CMCF-ID Health
Stubbs, Keith A.; Bacik, John‐Paul; Perley‐Robertson, G. Evan; Whitworth, Garrett E.; Gloster, Tracey M. et al. (2013). The Development of Selective Inhibitors of NagZ: Increased Susceptibility of Gram‐Negative Bacteria to β‐Lactams. ChemBioChem 14(15) , 1973-1981. 10.1002/cbic.201300395. [PDB: 4hzm] CMCF-ID Health
Suits, Michael D.; Boraston, Alisdair B. (2013). Structure of the Streptococcus pneumoniae Surface Protein and Adhesin PfbA. PLoS ONE 8(7) , e67190. 10.1371/journal.pone.0067190. [PDB: 3zpp] CMCF-ID Health
Sun, Tianjun; Hayakawa, Koto; Bateman, Katherine S.; Fraser, Marie E. (2010). Identification of the Citrate-binding Site of Human ATP-Citrate Lyase Using X-ray Crystallography. Journal of Biological Chemistry 285(35) , 27418-27428. 10.1074/jbc.m109.078667. [PDB: 3mwd] CMCF-ID Health
Sun, Tianjun; Hayakawa, Koto; Fraser, Marie E. (2011). ADP–Mg2+bound to the ATP-grasp domain of ATP-citrate lyase. Acta Crystallographica Section F Structural Biology and Crystallization Communications 67(10) , 1168-1172. 10.1107/s1744309111028363. [PDB: 3pff] CMCF-ID Health
Sun, Wanpeng; Geyer, C.; Yang, Jian (2008). Cloning, Expression, Purification and Crystallization of the PR Domain of Human Retinoblastoma Protein-Binding Zinc Finger Protein 1 (RIZ1). International Journal of Molecular Sciences 9(6) , 943-950. 10.3390/ijms9060943. CMCF-ID Health
Sweeting, Braden; Brown, Eric; Khan, M. Qasim; Chakrabartty, Avijit; Pai, Emil F. et al. (2013). N-Terminal Helix-Cap in α-Helix 2 Modulates β-State Misfolding in Rabbit and Hamster Prion Proteins. PLoS ONE 8(5) , e63047. 10.1371/journal.pone.0063047. [PDB: 4hls, 4hmm, 4hmr] CMCF-ID Health
Szewczyk, Paul; Tao, Houchao; McGrath, Aaron P.; Villaluz, Mark; Rees, Steven D. et al. (2015). Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein. Acta Crystallographica Section D Biological Crystallography 71(3) , 732-741. 10.1107/s1399004715000978. [PDB: 4q9i, 4q9j, 4q9l] CMCF-ID Health
Taylor, Alexander M.; Côté, Alexandre; Hewitt, Michael C.; Pastor, Richard; Leblanc, Yves et al. (2016). Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637). ACS Medicinal Chemistry Letters 7(5) , 531-536. 10.1021/acsmedchemlett.6b00075. [PDB: 5i83, 5i86] CMCF-ID Health
Taylor, Alexander M.; Vaswani, Rishi G.; Gehling, Victor S.; Hewitt, Michael C.; Leblanc, Yves et al. (2015). Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains. ACS Medicinal Chemistry Letters 7(2) , 145-150. 10.1021/ml500411h. [PDB: 4z1s] CMCF-ID Health
Tchigvintsev, Anatoli; Tchigvintsev, Dmitri; Flick, Robert; Popovic, Ana; Dong, Aiping et al. (2013). Biochemical and Structural Studies of Conserved Maf Proteins Revealed Nucleotide Pyrophosphatases with a Preference for Modified Nucleotides. Chemistry & Biology 20(11) , 1386-1398. 10.1016/j.chembiol.2013.09.011. [PDB: 4heb] CMCF-ID Health
Tebben, Andrew J.; Ruzanov, Maxim; Gao, Mian; Xie, Dianlin; Kiefer, Susan E. et al. (2016). Crystal structures of apo and inhibitor-bound TGFβR2 kinase domain: insights into TGFβR isoform selectivity. Acta Crystallographica Section D: Structural Biology 72(5) , 658-674. 10.1107/s2059798316003624. [PDB: 5e8u] CMCF-ID Health