Publication Beamlines Strategic Pillar
Reimer, Janice M.; Aloise, Martin N.; Harrison, Paul M.; Martin Schmeing, T. (2016). Synthetic cycle of the initiation module of a formylating nonribosomal peptide synthetase. Nature 529(7585) , 239-242. 10.1038/nature16503. [PDB: 5es5, 5es6, 5es7, 5es8, 5es9] CMCF-ID Health
Reimer, Janice M.; Aloise, Martin N.; Powell, Harold R.; Schmeing, T. Martin (2016). Manipulation of an existing crystal form unexpectedly results in interwoven packing networks with pseudo-translational symmetry. Acta Crystallographica Section D: Structural Biology 72(10) , 1130-1136. 10.1107/s2059798316013504. [PDB: 5jnf] CMCF-ID Health
René, Olivier; Fauber, Benjamin P.; Boenig, Gladys de Leon; Burton, Brenda; Eidenschenk, Céline et al. (2014). Minor Structural Change to Tertiary Sulfonamide RORc Ligands Led to Opposite Mechanisms of Action. ACS Medicinal Chemistry Letters 6(3) , 276-281. 10.1021/ml500420y. [PDB: 4wqp] CMCF-ID Health
Reniere, Michelle L.; Ukpabi, Georgia N.; Harry, S. Reese; Stec, Donald F.; Krull, Robert et al. (2010). The IsdG-family of haem oxygenases degrades haem to a novel chromophore. Molecular Microbiology 75(6) , 1529-1538. 10.1111/j.1365-2958.2010.07076.x. [PDB: 3lgm, 3lgn] CMCF-ID Health
Ren, Li; Grina, Jonas; Moreno, David; Blake, James F.; Gaudino, John J. et al. (2015). Discovery of Highly Potent, Selective, and Efficacious Small Molecule Inhibitors of ERK1/2. Journal of Medicinal Chemistry 58(4) , 1976-1991. 10.1021/jm501921k. [PDB: 4xj0] CMCF-ID Health
Richter, Jeremy M.; Cheney, Daniel L.; Bates, J. Alex; Wei, Anzhi; Luettgen, Joseph M. et al. (2016). Design and Synthesis of Novel Meta-Linked Phenylglycine Macrocyclic FVIIa Inhibitors. ACS Medicinal Chemistry Letters 8(1) , 67-72. 10.1021/acsmedchemlett.6b00375. [PDB: 5tqe] CMCF-ID Health
Robb, Melissa; Robb, Craig S.; Higgins, Melanie A.; Hobbs, Joanne K.; Paton, James C. et al. (2015). A Second β-Hexosaminidase Encoded in the Streptococcus pneumoniae Genome Provides an Expanded Biochemical Ability to Degrade Host Glycans. Journal of Biological Chemistry 290(52) , 30888-30900. 10.1074/jbc.m115.688630. [PDB: 5a6a, 5a6b, 5a6k, 5ac5] CMCF-ID Health
Roberts, Joseph N.; Singh, Rahul; Grigg, Jason C.; Murphy, Michael E. P.; Bugg, Timothy D. H. et al. (2011). Characterization of Dye-Decolorizing Peroxidases from Rhodococcus jostii RHA1. Biochemistry 50(23) , 5108-5119. 10.1021/bi200427h. [PDB: 3qnr] CMCF-ID Health
Rutaganira, Florentine U.; Fowler, Melissa L.; McPhail, Jacob A.; Gelman, Michael A.; Nguyen, Khanh et al. (2016). Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβ. Journal of Medicinal Chemistry 59(5) , 1830-1839. 10.1021/acs.jmedchem.5b01311. [PDB: 5euq] CMCF-ID Health
Sack, John S.; Gao, Mian; Kiefer, Susan E.; Myers, Joseph E.; Newitt, John A. et al. (2016). Crystal structure of microtubule affinity-regulating kinase 4 catalytic domain in complex with a pyrazolopyrimidine inhibitor. Acta Crystallographica Section F:Structural Biology Communications 72(2) , 129-134. 10.1107/s2053230x15024747. [PDB: 5es1] CMCF-ID Health
Safaee, Nozhat; Kozlov, Guennadi; Noronha, Anne M.; Xie, Jingwei; Wilds, Christopher J. et al. (2012). Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G. Molecular Cell 48(3) , 375-386. 10.1016/j.molcel.2012.09.001. [PDB: 4f02] CMCF-ID Health
Sarhan, Maen F.; Tung, Ching-Chieh; Van Petegem, Filip; Ahern, Christopher A. (2012). Crystallographic basis for calcium regulation of sodium channels. Proceedings of the National Academy of Sciences of the United States of America 109(9) , 3558-3563. 10.1073/pnas.1114748109. [PDB: 4djc] CMCF-ID Health
Scapin, Giovanna; Yang, Xiaoyu; Prosise, Winifred W; McCoy, Mark; Reichert, Paul et al. (2015). Structure of full-length human anti-PD1 therapeutic IgG4 antibody pembrolizumab. Nature Structural and Molecular Biology 22(12) , 953-958. 10.1038/nsmb.3129. [PDB: 5dk3] CMCF-ID Health
Schellenberg, Matthew J; Wu, Tao; Ritchie, Dustin B; Fica, Sebastian; Staley, Jonathan P et al. (2013). A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nature Structural and Molecular Biology 20(6) , 728-734. 10.1038/nsmb.2556. [PDB: 4jk7, 4jk8, 4jk9, 4jka, 4jkb, 4jkc, 4jkh] CMCF-ID Health
Schmidt, Michael M.; Townson, Sharon A.; Andreucci, Amy J.; King, Bracken M.; Schirmer, Emily B. et al. (2013). Crystal Structure of an HSA/FcRn Complex Reveals Recycling by Competitive Mimicry of HSA Ligands at a pH-Dependent Hydrophobic Interface. Structure 21(11) , 1966-1978. 10.1016/j.str.2013.08.022. [PDB: 4k71] CMCF-ID Health