| Taylor, Alexander M.; Vaswani, Rishi G.; Gehling, Victor S.; Hewitt, Michael C.; Leblanc, Yves et al. (2015). Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains. ACS Medicinal Chemistry Letters 7(2) , 145-150. 10.1021/ml500411h. [PDB: 4z1s] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Tchigvintsev, Anatoli; Tchigvintsev, Dmitri; Flick, Robert; Popovic, Ana; Dong, Aiping et al. (2013). Biochemical and Structural Studies of Conserved Maf Proteins Revealed Nucleotide Pyrophosphatases with a Preference for Modified Nucleotides. Chemistry & Biology 20(11) , 1386-1398. 10.1016/j.chembiol.2013.09.011. [PDB: 4heb] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Tebben, Andrew J.; Ruzanov, Maxim; Gao, Mian; Xie, Dianlin; Kiefer, Susan E. et al. (2016). Crystal structures of apo and inhibitor-bound TGFβR2 kinase domain: insights into TGFβR isoform selectivity. Acta Crystallographica Section D: Structural Biology 72(5) , 658-674. 10.1107/s2059798316003624. [PDB: 5e8u] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Tempel, Wolfram; Grabovec, Irina; MacKenzie, Farrell; Dichenko, Yaroslav V.; Usanov, Sergey A. et al. (2014). Structural characterization of human cholesterol 7α-hydroxylase. Journal of Lipid Research 55(9) , 1925-1932. 10.1194/jlr.m050765. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Thede, Gina L.; Arthur, David C.; Edwards, Ross A.; Buelow, Daelynn R.; Wong, Julia L. et al. (2011). Structure of the Periplasmic Stress Response Protein CpxP. Journal of Bacteriology 193(9) , 2149-2157. 10.1128/jb.01296-10. [PDB: 3qzc] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Thi, Nhung Nguyen; Offen, Wendy A.; Shareck, François; Davies, Gideon J.; Doucet, Nicolas et al. (2014). Structure and Activity of the Streptomyces coelicolor A3(2) β-N-Acetylhexosaminidase Provides Further Insight into GH20 Family Catalysis and Inhibition. Biochemistry 53(11) , 1789-1800. 10.1021/bi401697j. [PDB: 4c7f] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Thomas SPRETER VON KREUDENSTEIN; Surjit Bhimarao Dixit (2013). Stable Heterodimeric Antibody Design with Mutations in the Fc Domain. Patent Number: US20130195849A1. |
CMCF-BM |
Patent |
Health |
| Tokarski, John S.; Zupa-Fernandez, Adriana; Tredup, Jeffrey A.; Pike, Kristen; Chang, ChiehYing et al. (2015). Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain. Journal of Biological Chemistry 290(17) , 11061-11074. 10.1074/jbc.m114.619502. [PDB: 4wov] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Tonkin, Michelle L.; Beck, Josh R.; Bradley, Peter J.; Boulanger, Martin J. (2014). The Inner Membrane Complex Sub-compartment Proteins Critical for Replication of the Apicomplexan Parasite Toxoplasma gondii Adopt a Pleckstrin Homology Fold. Journal of Biological Chemistry 289(20) , 13962-13973. 10.1074/jbc.m114.548891. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Tonkin, Michelle L.; Crawford, Joanna; Lebrun, Maryse L.; Boulanger, Martin J. (2012). Babesia divergensandNeospora caninumapical membrane antigen 1 structures reveal selectivity and plasticity in apicomplexan parasite host cell invasion. Protein Science 22(1) , 114-127. 10.1002/pro.2193. [PDB: 4apl] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Tonkin, Michelle Lorine (2014). Molecular Strategies for Active Host Cell Invasion by Apicomplexan Parasites. Supervisor: Boulanger, Martin. British Columbia, Canada: University of Victoria. http://hdl.handle.net/1828/5496. |
CMCF-ID |
Doctoral Thesis |
Health |
| Tonkin, Michelle L.; Roques, Magali; Lamarque, Mauld H.; Pugnière, Martine; Douguet, Dominique et al. (2011). Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of AMA1 with a RON2 Peptide. Science 333(6041) , 463-467. 10.1126/science.1204988. [PDB: 2y8s, 2y8t] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Tonkin, M.L.; Crawford, J.; Lebrun, M.L.; Boulanger, M.J. (2012). Crystal Structure of AMA1 from Neospora caninum. Protein Data Bank: 4apl. |
CMCF-ID |
PDB Deposition |
Health |
| Tonkin, M.L.; Roques, M.; Lamarque, M.H.; Pugniere, M.; Douguet, D. et al. (2011). Co-structure of AMA1 with a surface exposed region of RON2 from Toxoplasma gondii. Protein Data Bank: 2y8t. |
CMCF-ID |
PDB Deposition |
Health |
| Tonkin, M.L.; Roques, M.; Lamarque, M.H.; Pugniere, M.; Douguet, D. et al. (2011). Co-structure of an AMA1 mutant (Y230A) with a surface exposed region of RON2 from Toxoplasma gondii. Protein Data Bank: 2y8s. |
CMCF-ID |
PDB Deposition |
Health |