Publication Beamlines Strategic Pillar
Hehemann, Jan-Hendrik; Kelly, Amelia G.; Pudlo, Nicholas A.; Martens, Eric C.; Boraston, Alisdair B. et al. (2012). Bacteria of the human gut microbiome catabolize red seaweed glycans with carbohydrate-active enzyme updates from extrinsic microbes. Proceedings of the National Academy of Sciences of the United States of America 109(48) , 19786-19791. 10.1073/pnas.1211002109. [PDB: 4aw7] CMCF-ID Health
Heald, Robert; Bowman, Krista K.; Bryan, Marian C.; Burdick, Daniel; Chan, Bryan et al. (2015). Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study. Journal of Medicinal Chemistry 58(22) , 8877-8895. 10.1021/acs.jmedchem.5b01412. [PDB: 5cal, 5cao, 5cap] CMCF-ID Health
Harikrishnan, Lalgudi S.; Kamau, Muthoni G.; Wan, Honghe; Inghrim, Jennifer A.; Zimmermann, Kurt et al. (2011). Pyrrolo[1,2-f]triazines as JAK2 inhibitors: Achieving potency and selectivity for JAK2 over JAK3. Bioorganic and Medicinal Chemistry Letters 21(5) , 1425-1428. 10.1016/j.bmcl.2011.01.022. [PDB: 3q32] CMCF-ID Health
Haji-Ghassemi, Omid; Müller-Loennies, Sven; Saldova, Radka; Muniyappa, Mohankumar; Brade, Lore et al. (2014). Groove-type Recognition of Chlamydiaceae-specific Lipopolysaccharide Antigen by a Family of Antibodies Possessing an Unusual Variable Heavy Chain N-Linked Glycan. Journal of Biological Chemistry 289(24) , 16644-16661. 10.1074/jbc.m113.528224. [PDB: 4m7j, 4m7z, 4m93, 4ma1] CMCF-ID Health
Haji-Ghassemi, Omid; Müller-Loennies, Sven; Rodriguez, Teresa; Brade, Lore; Kosma, Paul et al. (2015). Structural Basis for Antibody Recognition of Lipid A. Journal of Biological Chemistry 290(32) , 19629-19640. 10.1074/jbc.m115.657874. [PDB: 4odt, 4odu, 4odv, 4odw, 4z8f, 4z95] CMCF-ID Health
Haji-Ghassemi, Omid; Gilbert, Michel; Spence, Jenifer; Schur, Melissa J.; Parker, Matthew J. et al. (2016). Molecular Basis for Recognition of the Cancer Glycobiomarker, LacdiNAc (GalNAc[β1→4]GlcNAc), by Wisteria floribunda Agglutinin. Journal of Biological Chemistry 291(46) , 24085-24095. 10.1074/jbc.m116.750463. [PDB: 5kxb, 5kxc, 5kxd, 5kxe] CMCF-ID Health
Hackos, David H.; Lupardus, Patrick J.; Grand, Teddy; Chen, Yelin; Wang, Tzu-Ming et al. (2016). Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function. Neuron 89(5) , 983-999. 10.1016/j.neuron.2016.01.016. [PDB: 5h8h] CMCF-ID Health
Guo, Chuangxing; Linton, Angelica; Jalaie, Mehran; Kephart, Susan; Ornelas, Martha et al. (2013). Discovery of 2-((1H-benzo[d]imidazol-1-yl)methyl)-4H-pyrido[1,2-a]pyrimidin-4-ones as novel PKM2 activators. Bioorganic and Medicinal Chemistry Letters 23(11) , 3358-3363. 10.1016/j.bmcl.2013.03.090. [PDB: 4jpg] CMCF-ID Health
Gruninger, Robert J.; Thibault, John; Capeness, Michael J.; Till, Robert; Mosimann, Steven C. et al. (2014). Structural and Biochemical Analysis of a Unique Phosphatase from Bdellovibrio bacteriovorus Reveals Its Structural and Functional Relationship with the Protein Tyrosine Phosphatase Class of Phytase. PLoS ONE 9(4) , e94403. 10.1371/journal.pone.0094403. [PDB: 4nx8] CMCF-ID Health
Gritzalis, Dimitrios; Park, Jaeok; Chiu, Wei; Cho, Hyungjun; Lin, Yih-Shyan et al. (2015). Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase. Bioorganic and Medicinal Chemistry Letters 25(5) , 1117-1123. 10.1016/j.bmcl.2014.12.089. [PDB: 4qxs] CMCF-ID Health
Grishin, Andrey M.; Condos, Tara E.C.; Barber, Kathryn R.; Campbell-Valois, François-Xavier; Parsot, Claude et al. (2014). Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG. Structure 22(6) , 878-888. 10.1016/j.str.2014.04.010. [PDB: 4q5e, 4q5h] CMCF-ID Health
Grishin, Andrey M.; Cherney, Maia; Anderson, Deborah H.; Phanse, Sadhna; Babu, Mohan et al. (2014). NleH Defines a New Family of Bacterial Effector Kinases. Structure 22(2) , 250-259. 10.1016/j.str.2013.11.006. [PDB: 4lrj, 4lrk] CMCF-ID Health
Grishin, Andrey M.; Ajamian, Eunice; Zhang, Linhua; Rouiller, Isabelle; Bostina, Mihnea et al. (2012). Protein-Protein Interactions in the β-Oxidation Part of the Phenylacetate Utilization Pathway. Journal of Biological Chemistry 287(45) , 37986-37996. 10.1074/jbc.m112.388231. [PDB: 4fzw] CMCF-ID Health
Grishin, Andrey M.; Ajamian, Eunice; Zhang, Linhua; Cygler, Miroslaw (2010). Crystallization and preliminary X-ray analysis of PaaAC, the main component of the hydroxylase of theEscherichia coliphenylacetyl-coenzyme A oxygenase complex. Acta Crystallographica Section F Structural Biology and Crystallization Communications 66(9) , 1045-1049. 10.1107/s174430911002748x. CMCF-ID Health
Grishin, Andrey M.; Ajamian, Eunice; Tao, Limei; Zhang, Linhua; Menard, Robert et al. (2011). Structural and Functional Studies of the Escherichia coli Phenylacetyl-CoA Monooxygenase Complex. Journal of Biological Chemistry 286(12) , 10735-10743. 10.1074/jbc.m110.194423. [PDB: 3pvr, 3pvt, 3pvy, 3pw1, 3pw8, 3pwq] CMCF-ID Health