Publication Beamlines Strategic Pillar
Bloudoff, Kristjan; Fage, Christopher D.; Marahiel, Mohamed A.; Schmeing, T. Martin (2016). Structural and mutational analysis of the nonribosomal peptide synthetase heterocyclization domain provides insight into catalysis. Proceedings of the National Academy of Sciences of the United States of America 114(1) , 95-100. 10.1073/pnas.1614191114. [PDB: 5t3e] CMCF-ID Health
Bloudoff, Kristjan; Alonzo, Diego A.; Schmeing, T. Martin (2016). Chemical Probes Allow Structural Insight into the Condensation Reaction of Nonribosomal Peptide Synthetases. Cell Chemical Biology 23(3) , 331-339. 10.1016/j.chembiol.2016.02.012. [PDB: 5du9, 5dua] CMCF-ID Health
Blattner, Claudia; Lee, Jeong Hyun; Sliepen, Kwinten; Derking, Ronald; Falkowska, Emilia et al. (2014). Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers. Immunity 40(5) , 669-680. 10.1016/j.immuni.2014.04.008. [PDB: 4nug] CMCF-ID Health
Blake, James F.; Burkard, Michael; Chan, Jocelyn; Chen, Huifen; Chou, Kang-Jye et al. (2016). Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development. Journal of Medicinal Chemistry 59(12) , 5650-5660. 10.1021/acs.jmedchem.6b00389. [PDB: 5k4i] CMCF-ID Health
Blackler, Ryan J; Evans, Dylan W; Smith, David F; Cummings, Richard D; Brooks, Cory L et al. (2015). Single-chain antibody-fragment M6P-1 possesses a mannose 6-phosphate monosaccharide-specific binding pocket that distinguishesN-glycan phosphorylation in a branch-specific manner. Glycobiology 26(2) , 181-192. 10.1093/glycob/cwv093. [PDB: 4rzc] CMCF-ID Health
Bie, Haiying; Yin, Jiang; He, Xu; Kermode, Allison R; Goddard-Borger, Ethan D et al. (2013). Insights into mucopolysaccharidosis I from the structure and action of α-L-iduronidase. Nature Chemical Biology 9(11) , 739-745. 10.1038/nchembio.1357. [PDB: 4mj2, 4mj4] CMCF-BM, CMCF-ID Health
Bie, Haiying; Yin, Jiang; He, Xu; Kermode, Allison R; Goddard-Borger, Ethan D et al. (2013). Insights into mucopolysaccharidosis I from the structure and action of α-L-iduronidase. Nature Chemical Biology 9(11) , 739-745. 10.1038/nchembio.1357. [PDB: 4mj2, 4mj4] CMCF-BM, CMCF-ID Health
Beyrakhova, Ksenia A.; van Straaten, Karin; Li, Lei; Boniecki, Michal T.; Anderson, Deborah H. et al. (2016). Structural and Functional Investigations of the Effector Protein LpiR1 from Legionella pneumophila. Journal of Biological Chemistry 291(30) , 15767-15777. 10.1074/jbc.m115.708701. [PDB: 5fia, 5jg4] CMCF-ID Health
Bertwistle, Drew; Vogt, Linda; Aamudalapalli, Hari Babu; Palmer, David R. J.; Sanders, David A. R. et al. (2014). Purification, crystallization and room-temperature X-ray diffraction of inositol dehydrogenase LcIDH2 fromLactobacillus caseiBL23. Acta Crystallographica Section F Structural Biology and Crystallization Communications 70(7) , 979-983. 10.1107/s2053230x14011595. CMCF-ID Health
Bergeron, Julien R. C.; Worrall, Liam J.; Sgourakis, Nikolaos G.; DiMaio, Frank; Pfuetzner, Richard A. et al. (2013). A Refined Model of the Prototypical Salmonella SPI-1 T3SS Basal Body Reveals the Molecular Basis for Its Assembly. PLoS Pathogens 9(4) , e1003307. 10.1371/journal.ppat.1003307. [PDB: 4g08, 4g1i, 4g2s] CMCF-ID Health
Bergeron, Julien R.C.; Worrall, Liam J.; De, Soumya; Sgourakis, Nikolaos G.; Cheung, Adrienne H. et al. (2015). The Modular Structure of the Inner-Membrane Ring Component PrgK Facilitates Assembly of the Type III Secretion System Basal Body. Structure 23(1) , 161-172. 10.1016/j.str.2014.10.021. [PDB: 4oyc, 4w4m] CMCF-BM Health
Bergeron, Julien R.C.; Fernández, Lucia; Wasney, Gregory A.; Vuckovic, Marija; Reffuveille, Fany et al. (2016). The Structure of a Type 3 Secretion System (T3SS) Ruler Protein Suggests a Molecular Mechanism for Needle Length Sensing. Journal of Biological Chemistry 291(4) , 1676-1691. 10.1074/jbc.m115.684423. [PDB: 5cuk, 5cul] CMCF-BM, CMCF-ID Health
Bergeron, Julien R.C.; Fernández, Lucia; Wasney, Gregory A.; Vuckovic, Marija; Reffuveille, Fany et al. (2016). The Structure of a Type 3 Secretion System (T3SS) Ruler Protein Suggests a Molecular Mechanism for Needle Length Sensing. Journal of Biological Chemistry 291(4) , 1676-1691. 10.1074/jbc.m115.684423. [PDB: 5cuk, 5cul] CMCF-BM, CMCF-ID Health
Bello, Angelica M.; Poduch, Ewa; Liu, Yan; Wei, Lianhu; Crandall, Ian et al. (2008). Structure–Activity Relationships of C6-Uridine Derivatives Targeting Plasmodia Orotidine Monophosphate Decarboxylase. Journal of Medicinal Chemistry 51(3) , 439-448. 10.1021/jm7010673. [PDB: 3bar] CMCF-ID Health
Bello, Angelica M.; Konforte, Danijela; Poduch, Ewa; Furlonger, Caren; Wei, Lianhu et al. (2009). Structure−Activity Relationships of Orotidine-5′-Monophosphate Decarboxylase Inhibitors as Anticancer Agents. Journal of Medicinal Chemistry 52(6) , 1648-1658. 10.1021/jm801224t. [PDB: 3g3m] CMCF-ID Health