Blake, James F.; Burkard, Michael; Chan, Jocelyn; Chen, Huifen; Chou, Kang-Jye et al. (2016). Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development. Journal of Medicinal Chemistry 59(12) , 5650-5660. 10.1021/acs.jmedchem.6b00389. [PDB: 5k4i] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Blackler, Ryan J; Evans, Dylan W; Smith, David F; Cummings, Richard D; Brooks, Cory L et al. (2015). Single-chain antibody-fragment M6P-1 possesses a mannose 6-phosphate monosaccharide-specific binding pocket that distinguishesN-glycan phosphorylation in a branch-specific manner. Glycobiology 26(2) , 181-192. 10.1093/glycob/cwv093. [PDB: 4rzc] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Bie, H.Y.; Yin, J.; James, M.N.G.; TB Structural Genomics Consortium (TBSGC) (2016). Crystal structure of beta subunit of acyl-CoA carboxylase AccD1 from Mycobacterium tuberculosis. Protein Data Bank: 4q0g. |
CMCF-ID |
PDB Deposition |
Health |
Bie, H.; Yin, J.; He, X.; Kermode, A.R.; Goddard-Borger, E.D. et al. (2013). Human iduronidase apo structure P21 form. Protein Data Bank: 4mj4. |
CMCF-ID |
PDB Deposition |
Health |
Bie, Haiying; Yin, Jiang; He, Xu; Kermode, Allison R; Goddard-Borger, Ethan D et al. (2013). Insights into mucopolysaccharidosis I from the structure and action of α-L-iduronidase. Nature Chemical Biology 9(11) , 739-745. 10.1038/nchembio.1357. [PDB: 4mj2, 4mj4] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Beyrakhova, K.; van Straaten, K.; Cygler, M. (2016). Structure of the effector protein LpiR1 (Lpg0634) from Legionella pneumophila. Protein Data Bank: 5jg4. |
CMCF-ID |
PDB Deposition |
Health |
Beyrakhova, K.; van Straaten, K.; Cygler, M. (2016). Structure of the effector protein LpiR1 (Lpg0634) from Legionella pneumophila. Protein Data Bank: 5fia. |
CMCF-ID |
PDB Deposition |
Health |
Beyrakhova, Ksenia A.; van Straaten, Karin; Li, Lei; Boniecki, Michal T.; Anderson, Deborah H. et al. (2016). Structural and Functional Investigations of the Effector Protein LpiR1 from Legionella pneumophila. Journal of Biological Chemistry 291(30) , 15767-15777. 10.1074/jbc.m115.708701. [PDB: 5fia, 5jg4] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Bertwistle, Drew; Vogt, Linda; Aamudalapalli, Hari Babu; Palmer, David R. J.; Sanders, David A. R. et al. (2014). Purification, crystallization and room-temperature X-ray diffraction of inositol dehydrogenase LcIDH2 fromLactobacillus caseiBL23. Acta Crystallographica Section F Structural Biology and Crystallization Communications 70(7) , 979-983. 10.1107/s2053230x14011595. |
CMCF-ID |
Peer-Reviewed Article |
Health |
Bergeron, Julien R. C.; Worrall, Liam J.; Sgourakis, Nikolaos G.; DiMaio, Frank; Pfuetzner, Richard A. et al. (2013). A Refined Model of the Prototypical Salmonella SPI-1 T3SS Basal Body Reveals the Molecular Basis for Its Assembly. PLoS Pathogens 9(4) , e1003307. 10.1371/journal.ppat.1003307. [PDB: 4g08, 4g1i, 4g2s] |
CMCF-ID |
Peer-Reviewed Article |
Health |
Bergeron, Julien R.C.; Fernández, Lucia; Wasney, Gregory A.; Vuckovic, Marija; Reffuveille, Fany et al. (2016). The Structure of a Type 3 Secretion System (T3SS) Ruler Protein Suggests a Molecular Mechanism for Needle Length Sensing. Journal of Biological Chemistry 291(4) , 1676-1691. 10.1074/jbc.m115.684423. [PDB: 5cuk, 5cul] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Bergeron, J.R.C.; Worrall, L.J.; Strynadka, N.C.J. (2013). Structure of the PrgH periplasmic domain. Protein Data Bank: 4g1i. |
CMCF-ID |
PDB Deposition |
Health |
Bergeron, J.R.C.; Strynadka, N.C.J. (2015). crystal structure of the PscU C-terminal domain. Protein Data Bank: 5cul. |
CMCF-ID |
PDB Deposition |
Health |
Bergeron, J.R.C.; Strynadka, N.C.J. (2015). Crystal structure of the PscP SS domain. Protein Data Bank: 5cuk. |
CMCF-ID |
PDB Deposition |
Health |
Bergeron, J.R.C.; Strynadka, N.C.J. (2014). Crystal structure of PrgK 19-92. Protein Data Bank: 4w4m. |
CMCF-ID |
PDB Deposition |
Health |