Publication Beamlines Strategic Pillar
Shin, Youngsook; Suchomel, Julia; Cardozo, Mario; Duquette, Jason; He, Xiao et al. (2015). Discovery, Optimization, and in Vivo Evaluation of Benzimidazole Derivatives AM-8508 and AM-9635 as Potent and Selective PI3Kδ Inhibitors. Journal of Medicinal Chemistry 59(1) , 431-447. 10.1021/acs.jmedchem.5b01651. [PDB: 5eds] CMCF-ID Health
Shi, Kun; Houston, Douglas R.; Berghuis, Albert M. (2011). Crystal Structures of Antibiotic-Bound Complexes of Aminoglycoside 2′′-Phosphotransferase IVa Highlight the Diversity in Substrate Binding Modes among Aminoglycoside Kinases. Biochemistry 50(28) , 6237-6244. 10.1021/bi200747f. [PDB: 3sg8] CMCF-ID Health
Shaw, Alice T.; Friboulet, Luc; Leshchiner, Ignaty; Gainor, Justin F.; Bergqvist, Simon et al. (2016). Resensitization to Crizotinib by the LorlatinibALKResistance Mutation L1198F. New England Journal of Medicine 374(1) , 54-61. 10.1056/nejmoa1508887. [PDB: 5a9u, 5aac] CMCF-ID Health
Shala, Agnesa; Patel, Kevin H.; Golemi-Kotra, Dasantila; Audette, Gerald F. (2013). Expression, purification, crystallization and preliminary X-ray analysis of the receiver domain ofStaphylococcus aureusLytR protein. Acta Crystallographica Section F Structural Biology and Crystallization Communications 69(12) , 1418-1421. 10.1107/s1744309113030972. CMCF-ID Health
Schroeder, Gretchen M.; Wei, Donna; Banfi, Patrizia; Cai, Zhen-Wei; Lippy, Jonathan et al. (2012). Pyrazole and pyrimidine phenylacylsulfonamides as dual Bcl-2/Bcl-xL antagonists. Bioorganic and Medicinal Chemistry Letters 22(12) , 3951-3956. 10.1016/j.bmcl.2012.04.106. [PDB: 4ehr] CMCF-ID Health
Schmidt, Michael M.; Townson, Sharon A.; Andreucci, Amy J.; King, Bracken M.; Schirmer, Emily B. et al. (2013). Crystal Structure of an HSA/FcRn Complex Reveals Recycling by Competitive Mimicry of HSA Ligands at a pH-Dependent Hydrophobic Interface. Structure 21(11) , 1966-1978. 10.1016/j.str.2013.08.022. [PDB: 4k71] CMCF-ID Health
Schellenberg, Matthew J; Wu, Tao; Ritchie, Dustin B; Fica, Sebastian; Staley, Jonathan P et al. (2013). A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nature Structural and Molecular Biology 20(6) , 728-734. 10.1038/nsmb.2556. [PDB: 4jk7, 4jk8, 4jk9, 4jka, 4jkb, 4jkc, 4jkh] CMCF-ID Health
Scapin, Giovanna; Yang, Xiaoyu; Prosise, Winifred W; McCoy, Mark; Reichert, Paul et al. (2015). Structure of full-length human anti-PD1 therapeutic IgG4 antibody pembrolizumab. Nature Structural and Molecular Biology 22(12) , 953-958. 10.1038/nsmb.3129. [PDB: 5dk3] CMCF-ID Health
Sarhan, Maen F.; Tung, Ching-Chieh; Van Petegem, Filip; Ahern, Christopher A. (2012). Crystallographic basis for calcium regulation of sodium channels. Proceedings of the National Academy of Sciences of the United States of America 109(9) , 3558-3563. 10.1073/pnas.1114748109. [PDB: 4djc] CMCF-ID Health
Samborska, Bożena; Kimber, Matthew S. (2012). A Dodecameric CcmK2 Structure Suggests β-Carboxysomal Shell Facets Have a Double-Layered Organization. Structure 20(8) , 1353-1362. 10.1016/j.str.2012.05.013. CMCF-ID Materials
Safaee, Nozhat; Noronha, Anne M.; Rodionov, Dmitry; Kozlov, Guennadi; Wilds, Christopher J. et al. (2013). Structure of the Parallel Duplex of Poly(A) RNA: Evaluation of a 50 Year-Old Prediction. Angewandte Chemie - International Edition 52(39) , 10370-10373. 10.1002/anie.201303461. [PDB: 4jrd] CMCF-ID Materials
Safaee, Nozhat; Kozlov, Guennadi; Noronha, Anne M.; Xie, Jingwei; Wilds, Christopher J. et al. (2012). Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G. Molecular Cell 48(3) , 375-386. 10.1016/j.molcel.2012.09.001. [PDB: 4f02] CMCF-ID Health
Saer, Rafael G.; Hardjasa, Amelia; Rosell, Federico I.; Mauk, A. Grant; Murphy, Michael E. P. et al. (2013). Role of Rhodobacter sphaeroides Photosynthetic Reaction Center Residue M214 in the Composition, Absorbance Properties, and Conformations of HA and BA Cofactors. Biochemistry 52(13) , 2206-2217. 10.1021/bi400207m. [PDB: 4in5] CMCF-ID Agriculture
Sack, John S.; Gao, Mian; Kiefer, Susan E.; Myers, Joseph E.; Newitt, John A. et al. (2016). Crystal structure of microtubule affinity-regulating kinase 4 catalytic domain in complex with a pyrazolopyrimidine inhibitor. Acta Crystallographica Section F:Structural Biology Communications 72(2) , 129-134. 10.1107/s2053230x15024747. [PDB: 5es1] CMCF-ID Health
Rutaganira, Florentine U.; Fowler, Melissa L.; McPhail, Jacob A.; Gelman, Michael A.; Nguyen, Khanh et al. (2016). Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβ. Journal of Medicinal Chemistry 59(5) , 1830-1839. 10.1021/acs.jmedchem.5b01311. [PDB: 5euq] CMCF-ID Health